Drug Week
Susan Hasty, Publisher
Table of Contents . . . October 14th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Drug Week | Other Publications
Anti-Infectives - Colistin i.v. effective for control of multiresistant Gram-negative pathogens
Cancer Therapy - Aplidin combination trials initiated for metastatic malignant melanoma
Drug Development - Phase III trial initiated to evaluate anemia treatment in heart failure patients
Pain Management - Positive phase III clinical results for Remoxy reported
Pain Management - Statistically significant analgesic effects of bicifadine in phase III announced
Addiction Medicine - Mu agonist efficacy affects LAAM, buprenorphine cross-tolerance
Adverse Drug Reaction - Australian Agency urges caution over Paroxetine during pregnancy
Adverse Drug Reaction - Combination therapy containing pegylated interferon produces weight loss
Adverse Drug Reaction - Study found poor knowledge of the side effects of ACE-I
Alcohol Use - Ethanol exposure before injury impairs angiogenesis and wound healing activity
Allergy & Immunology - Antibody to transglutaminase denotes the presence of chronic liver diseases
Angiology - Recent findings illuminate research in angiology
Alzheimer Disease - Alzheimer disease study with Dimebon initiated
Alzheimer Disease - Clinical benefit of cholinesterase inhibitors questioned
Alzheimer Disease - European phase III trial of Alzhemed launched
Alzheimer Disease - Muscimol lowers amyloid beta-induced toxicity in rat cortical cells
Alzheimer Disease Therapy - High-concentration galantamine formulation developed for intranasal delivery
Anemia - Epoetin with iron given to anemic patients not receiving anticancer treatment
Angiology - Reports add new data to angiology research
Anesthesia - Peribulbar analgesics cause increases in BP and mild bradycardia
Angiology - Acetylcholine may initiate two competing responses in mouse arteries
Angiology - New data illuminates research in angiology
Angiology - Researchers report details of new studies and findings in the area of angiology
Angiotensin - Researchers describe findings in angiotensin studies
Anthrax Vaccine Development - Antibody patterns in anthrax vaccinees reported
Anti-Inflammatory - Effects of gamma irradiation and Ginkgo biloba characterized
Antibacterial Agents - Glycopeptide antibiotic, activity of alkyl derivatives determined
Antibacterial Agents - Use of antibiotics for acne may increase risk of common illness
Antibacterial Agents - Virginiamycin M-1 analyzed, conformational flexibility revealed
Breast Cancer - Recent findings in breast cancer described
Anticonvulsant Therapy - Rate of phenytoin-carbamazepine cross-reaction determined
Antimicrobial Resistance - Cross-resistance to antibiotics in M. tuberculosis examined
Antimicrobials - Antimicrobial company provides European market update
Antioxidants - Antioxidant vitamins prevented second primary cancers in head and neck cancers
Antioxidants - Effects of Turkish pollen and propolis extracts examined
Breast Cancer - Reports describe recent advances in breast cancer research
Anxiety Therapy - Dipeptide LY354740 prodrug developed
Apoptosis - Effects of diethylstilbestrol in human lymphocytes in vitro explored
Apoptosis - Isothiocyanates induced cell apoptosis
Apoptosis - PI 3-kinase inhibitor synergizes with FAS siRNA to induce apoptosis in cancer
Asthma Therapy - Inhaler type doesn't affect budesonide efficacy
Atherosclerosis - Research in atherosclerosis provides new insights
Breast Cancer - Research add new data to breast cancer body of knowledge
Atherosclerosis Vaccine Development - Blockade of IL-12 by protein vaccination attenuates atherosclerosis
Attention Deficit Hyperactivity Disorder - Research reveals adult diagnosis of ADHD growing faster than children diagnosis
Autoimmune Hepatitis - Inadequate regulatory T-cell activity may initiate liver injury
Autoimmune Polyglandular Syndrome - Immunosuppressive therapy seems promising in some APECED cases
Avian Influenza - Report: Drug-resistant avian influenza viruses more common in Southeast Asia
Breast Cancer - Researchers provide details of new studies and findings in the area of breast cancer
Back Pain - Teriparatide tested against alendronate for back pain in women with osteoporosis
Bacteriology - Agrobacterium tumefaciens examined, type IV secretion apparatus clarified
Bacteriology - Morphological engineering of S. hygroscopicus studied for antibiotic yield
Bioethics - Issues on intellectual property and benefit-sharing discussed
Biomedical Engineering - Bioreactors leverage healing mechanisms to create bone and cartilage
Biomedical Engineering - Implants with slow released protein sustain cartilage vascularity and growth
Breast Cancer - Studies add new findings to breast cancer body of knowledge
Biomedical Engineering - Intrinsically radiopaque hydrogels proposed for nucleus pulposus replacement
Biotechnology - Hybridoma cell culture efficiency increases with metabolic control of nutrients
Bioterrorism - Inactivation of biological agents studied, use of dimethyldioxirane reported
Bladder Cancer - Endothelin axis is a target of the lung metastasis suppressor gene RhoGD12
Bladder Cancer - Hyperoxia provokes gemcitabine efficacy in transitional cell carcinoma
Bone Cancer - Extraskeletal osteosarcoma should be treated like conventional osteosarcoma
Breast Cancer - Studies describe new findings in breast cancer research
Bone Cancer - Prognostic factors and long-term outcome of metastatic osteosarcoma discussed
Brain Cancer - Recent findings illuminate research in brain cancer
Brain Metastases - Enrollment initiated for phase 2 trial of Xcytrin Injection
Breast Cancer - Addition of fulvestrant to endocrine treatment strategy evaluated
Breast Cancer - An orally bioavailable ER downregulator identified for breast cancer treatment
Breast Cancer - Bisphosphonates evaluated in patients with metastatic breast cancer
Cancer Vaccines - Findings advance knowledge in cancer vaccines research
Breast Cancer - Bisphosphonates used to manage bone metastases from breast cancer
Breast Cancer - Cisplatin-epirubicin-paclitaxel used to treat operable breast cancer
Breast Cancer - Cisplatinum and vinorelbine studied in phase II trial
Breast Cancer - European Mutual Recognition Procedure gives approval to market Aromasin
Breast Cancer - Findings advance knowledge in breast cancer research
Breast Cancer - Fourth phase III study shows Herceptin plus chemo improved disease-free survival
Cancer Vaccines - Research add new data to cancer vaccines body of knowledge
Breast Cancer - Inflammatory local recurrence occurred after breast-conservation therapy
Breast Cancer - Lower dose capecitabine demonstrated favorable therapeutic index
Breast Cancer - Molecular tumor subtype influences preoperative chemotherapy efficacy
Breast Cancer - Neoadjuvant docetaxel combined with adjuvant doxorubicin and cyclophosphamide
Cancer Vaccines - Studies add new findings to cancer vaccines body of knowledge
Breast Cancer - Temsirolimus evaluated as treatment in breast cancer
Breast Cancer - Trial data show benefits of combination therapy in early stage breast cancer
Diabetes Therapy - New research in the area of diabetes therapy detailed
Breast Cancer Therapy - Researchers study adjuvant chemotherapy in elderly breast cancer patients
Business & Finance - Canadian biopharmaceutical firm receives letter from majority note holder
Business & Finance - Drug companies follow spending trends regardless of product size
Business & Finance - IT company establishes life science division for pharma firms
Business & Finance - IT consultancy launched for health industry
Business & Finance - Nasally delivered drug maker reports new business strategy
Diabetes Therapy - Recent findings in diabetes therapy described
Business & Finance - Software launched for pharmaceutical marketing, sales
Business & Finance - U.S. FDA issues warning letter to Ceph International
Business & Finance - Vitrase maker presents clinical data at medical conferences
Business Update - Australian biopharma company announces intention to list Glycotex on Nasdaq
Business Update - Avonex maker announces initiative to drive long-term growth
Business Update - Cell therapy company facility will manufacture Cellerant Therapeutics' products
Diabetes Therapy - Recent findings in diabetes therapy provide new insights
Business Update - Laboratory products company adds three new analytes
Business Update - Letter of intent signed to acquire Mircette
Business Update - Physical therapy clinics experience limited impact from Hurricane Katrina
Business Update - R&D Center opens in China
Business Update - Society names Managed Care Interface its official journal
Business Update - Tracleer maker provides update on company's clinical pipeline
Diabetes Therapy - Reports describe recent advances in diabetes therapy research
Business Update - U.S. EPA extends and expands contract with genetics testing company
Cancer Prevention - Decision counseling in cancer prevention and control examined
Cancer Prevention - Interferon-alpha lowers proliferative activity in hepatitis C-infected livers
Cancer Research - Ipsogen, pharmacogenomics company ink cancer biomarker research agreements
Cancer Research - Protein p53 signaling of cell suicide offers insights for new anticancer drugs
Cancer Research - Steering committee assessment of GTI-2040 studies announced
Diabetes Therapy - Researchers detail new studies and findings in the area of diabetes therapy
Cancer Risk Factors - Exposure to hexachlorocyclohexane presented health risk in Tianjin, China
Cancer Therapy - A new therapy regimen is effective in patients with aggressive lymphoma
Cancer Therapy - Advances reported in therapy of diffuse large B-cell lymphoma
Cancer Therapy - Anti-vascular therapy evaluated with texture analysis
Cancer Therapy - Antitumor activity of HER-2 inhibitors examined
Cancer Therapy - Cancer gene vaccine shows promising safety results in Phase 2 lung cancer trial
Diabetes Therapy - Researchers provide details of new studies and findings in the area of diabetes therapy
Cancer Therapy - Chemotherapies have differential effects on proteins governing angiogenesis
Cancer Therapy - Chemotherapy-induced nausea/vomiting on women's functional status studied
Cancer Therapy - Compatibility and stability of Imexon in infusion devices examined
Cancer Therapy - Docetaxel and gemcitabine administered biweekly as first-line therapy for NSCLC
Cancer Therapy - Enrollment completed in BLP25 liposome vaccine phase II study
Cancer Therapy - Individualized adjuvant chemotherapy guided by chemosensitivity test
Diagnostics - Reports advance knowledge in diagnostics research
Cancer Therapy - Lower dose thalidomide fights metastatic renal cell cancer better
Cancer Therapy - MRI features of leukoencephalopathy following chemoradiotherapy studied
Cancer Therapy - Maspin makes prostate cancer cells more sensitive to doxazosin
Cancer Therapy - Metronomic therapy offers palliative treatment of metastatic breast cancer
Cancer Therapy - Neoadjuvant taxanes used in treatment of non-metastatic breast cancer
Cancer Therapy - Oleanolic acid and ursolic acid evaluated in anticancer chemotherapies
Diagnostics - Reports describe recent advances in diagnostics research
Cancer Therapy - Persulfides generated reactive oxygen species
Cancer Therapy - Reports add new data to cancer therapy research
Cancer Therapy - Sorafenib submitted to EMEA for approval as kidney cancer treatment
Cancer Therapy - Study of treatments for chemotherapy-related anemia published
Cancer Therapy - U.S. FDA approves IND application for phase II study of cancer drug Elacyt
Cancer Therapy - U.S. NIH grant to fund trial of PHP for melanoma, kidney cancer
Hypertension - Studies advance knowledge in hypertension research
Cancer Therapy - mTOR inhibitors augment the antiangiogenic value of radiation therapy
Cancer Vaccine Development - Immunization with p53- and K-ras-derived peptides in cancer examined
Cancer Vaccines - Antigen-presenting cells induce higher-avidity human CTLs
Cancer Vaccines - CD4+ T cells promote tumor growth by inhibiting tumor-specific T cells
Cancer Vaccines - CEA-based cancer vaccines reviewed
Cancer Vaccines - DNA vaccines activate antitumor immunity by engaging NKG2D receptor
Melanoma - Researchers publish new studies and findings in the area of melanoma
Cancer Vaccines - Data advance knowledge in cancer vaccines research
Cancer Vaccines - Human antibody inhibits IGF-IR signaling and tumor cell growth
Cancer Vaccines - Hypoxic cell radiosensitizer enhances anticancer host responses
Cancer Vaccines - Induction of T-cell responses to human stroma antigen examined
Cancer Vaccines - Introducing bonds into targeting moiety improves superantigen stability
Melanoma Vaccines - Researchers report details of new studies and findings in the area of melanoma vaccines
Cancer Vaccines - New CTL epitopes from two cancer germ line genes identified
Cancer Vaccines - Soluble protein antigen inhibits vaccine-induced anti-tumor response
Cardiology - Cardiology group has published a guide for pharmacologic control of heart rhythm
Cardiology - Cardiology group has published guidelines regarding anticoagulation
Myocardial Infarction - Findings advance knowledge in myocardial infarction research
Cardiology - Data showing cardiovascular benefits of treatment with perindopril published
Cardiology - Ginsenosides compound may attenuate GI injury and inflammation after bypass
Cardiology - Lipoic acid is protective in cyclophosphamide-induced cardiac injury
Cardiology - Rat model discounts microvascular rarefaction as a cause of hypertension
Cardiology - Review describes the beneficial effect of beta-blockers in noncardiac surgery
Cardiology - Study examined concomitant aspirin and ibuprofen use
Proteomics - Researchers provide details of new studies and findings in the area of proteomics
Cardiology - Study presents iron chelation as tool for preventing myocardial damage
Cardiology - iNOS inhibitor reduces side effects of NO in I/R injury
Cardiomyocytes - Nuclear-mitochondrial cross-talk in cardiomyocyte T3 signaling analyzed
Cardiomyocytes - h5-HT4 receptor isoforms are used to explore receptor signaling
Cardiovascular Disease - Investigational drug trans NV-04 phase Ib clinical trial testing complete
Cardiovascular Research - Cell signaling discovery yields clues to heart disease
SARS - Studies advance knowledge in SARS research
Cardiovascular Research - Conjugated oral BNP activates cGMP and significantly reduces MAP
Cardiovascular Research - NO system may be upregulated in CV system and kidney in senescence
Cardiovascular Research - Nitroglycerin activates brainstem areas implicated in nociception
Cardiovascular Research - Review examines evidence for gender differences in renal I/R injury
Cardiovascular Research - Strategies to increase ATP requirements may protect against occlusion
Catheter-Related Infection - Novel azole-resistant opportunistic yeast infection reported
Cell Biology - Bimolecular fluorescence complementation detects protein interactions
Cervical Cancer Screening - Alternate screening method for cervical cancer risk tested
Cervical Cancer Screening - Screening methods for cervical cancer compared
Chemotherapy - Antipyrine test predicted pharmacodynamics of docetaxel/cisplatin chemotherapy
Chemotherapy - Effects of early intervention with epoetin alfa analyzed
Cholangiocarcinoma - Phase II clinical protocol submitted for Davanat with 5-Fluorouracil
Chromhidrosis - Botulinum toxin therapy effective
Chronic Hepatitis B - Hepatitis B virus genotype C mutations accompany poor liver histology
Chronic Hepatitis C - Peginterferon alpha dosing strategies beat persistent hepatitis C
Chronic Liver Disease - Bacterial pathogens may be involved in the onset of primary biliary cirrhosis
Chronic Liver Disease - Response to corticosteroid hails good outcomes in severe alcoholic hepatitis
Chronic Pain - Biopharma company announces positive phase III results for Remoxy
Chronic Pain - Phase III studies of alvimopan for opioid-induced constipation begin
Chronic Periodontitis - Clinical trial results of Periowave photodynamic disinfection system released
Clinical Trials - Review summarizes trials that investigated effects of BP-lowering drugs
Clinical Trials - Trial for anticancer drug to shrink solid, lymph node, bone marrow tumors begun
Clinical Trials - Trial of oral small-molecule selective inhibitor in Crohn disease initiated
Clinical Trials - Value of confirming responses in oncological clinical trials assessed
Clinical Trials - Worldwide clinical trials portal launched
Cognitive Impairment - Horsetail extract improves cognition in rat model
Collaborations - Alliance to focus on discovery of small molecule therapeutic compounds
Collaborations - Antimicrobial company enters arrangement with Soilbind Limited
Collaborations - Collaboration inked for the R&D of non-nuclear contrast media
Collaborations - Collaboration to develop reformulated drug products using BioSilicon announced
Collaborations - Companies work to evaluate role of HIF-1alpha inhibition in treatment of cancer
Collaborations - Deal signed to develop rheumatoid arthritis treatment
Collaborations - Health science company and Eppendorf announce comarketing agreement
Collaborations - Institute of Systems Biology adopts nucleic acid labeling technology
Collaborations - License deal signed with European firm for calcium phosphate nanotechnology
Collaborations - Licensing, commercialization deal signed to advance microRNA research
Collaborations - Partnership provides mobile expense-management solutions for pharma field reps
Collaborations - Pharmaceutical companies enter strategic alliance for drug development, sales
Collaborations - Plaque excision device company and Merck enter drug development agreement
Collaborations - Research agreement signed for lung cancer research
Collaborations - Two distributor agreements signed for glycobiology enzymes
Colon Cancer - Butyrate inhibited cell invasion of human colon cancer cells
Colon Cancer Vaccine Development - Oral vaccine induces immune responses against carcinoembryonic antigen
Colorectal Cancer - Efficacy of fluorouracil-based first-line chemotherapy evaluated
Colorectal Cancer - Folate lowered risk of colorectal cancer in patients with ulcerative colitis
Colorectal Cancer - Neoadjuvant treatment of unresectable colorectal liver metastases discussed
Complementary & Alternative Medicine - Cardaria draba glucoraphanin extraction optimized with batch extraction
Complementary & Alternative Medicine - Carvacrol and eugenol may modulate immunoresponsive cell function
Complementary & Alternative Medicine - Cocoa flavanols heart-healthy snacks introduced
Complementary & Alternative Medicine - EPSF from Cordyceps sinensis has immunomodulatory and antitumor properties
Complementary & Alternative Medicine - Effects of Gami-Jeonggi-San on human endothelial cell investigated
Complementary & Alternative Medicine - Essential oil of C. boreale Makino induces apoptosis in carcinoma cells
Complementary & Alternative Medicine - Guided imagery evaluated as adjuvant cancer therapy
Complementary & Alternative Medicine - In vitro propagation method for Sternbergia clusiana established
Contraception - NuvaRing estrogen exposure proven lower than with patch or oral contraceptives
Critical Care Medicine - Utility of proton pump inhibitor delivery by nasogastric tube evaluated
Cytology - Cisplatin cytotoxicity analyzed, protective functional domain identified
Cytology - Endothelial microparticles influence angiogenic dysfunction
Cytology - Nicastrin analyzed, gamma-secretase-substrate receptor function revealed
Cytology - Phi endocytic motifs analyzed, non-canonical nature revealed
DNA Vaccines - Fusion protein ameliorates anti-tumor DNA vaccination
DNA Vaccines - Method to recover plasmid DNA based on aqueous two-phase separation
Dementia - Mechanisms of Choto-san's therapeutic effects determined
Dendritic Cell Vaccine - Antigen targeted to dendritic cells via humanized anti-DC-SIGN antibody
Dendritic Cell Vaccine - B7-DC cross-linking restores antigen uptake in mature dendritic cells
Dengue Fever - Castanospermine is a potent inhibitor of dengue virus infection
Dental Health - Mayo Clinic advises how to break the teeth-grinding habit
Dental Research - PRM did not significantly improve bone mineral density in dental implants
Dentistry - Impact of light activator type on bleaching efficacy determined
Dermatology - Companies announce agreements to expand collaboration on dermatology products
Dermatology - Epidermal organotypic model studied, Hoxb13 up-regulation defined
Dermatology - Ninety percent participation level in Phase 3 psoriasis extension trial reported
Diabetes Complications - Erythropoietin is a potent activator of proliferative diabetic retinopathy
Diabetes Complications - Insulin reduces plasma VEGF levels in children with new-onset diabetes
Diabetes Complications - Vitamin D receptor gene polymorphism raises diabetes retinopathy risk
Diabetes Management - Compound improves blood sugar of people on antidiabetic prescription, study show
Diabetes Therapy - Analogues of GIP possess antidiabetic activity
Diabetes Therapy - Antidiabetic drug utilization in Hungary reviewed
Diabetes Therapy - Findings in diabetes therapy provide new insights
Diabetes Therapy - Nonsteroidal glucocorticoid receptor modulators are antidiabetic
Diabetes Therapy - Pharmacological profile of novel, non-TZD PPAR-gamma agonist described
Diabetes Therapy - Therapeutic perspectives of adipocytokines reviewed
Diabetes Therapy - U.S. FDA approves NovoLog for treatment of diabetes in children
Diabetic Neuropathy - Topical formulation for diabetic neuropathy assessed in published study
Diagnostics - A new rapid test for hepatitis E enhances point-of-care testing
Diagnostics - Combination assay improves early detection of hepatitis C virus infection
Diagnostics - Data advance knowledge in diagnostics research
Diagnostics - Degenerate primers pinpoint multiple genotypes of woodchuck hepatitis virus
Diagnostics - Diagnosis of bacterial biofilms found in joint arthroplasty infections
Diagnostics - Dipstick assay offers visual detection of multiple nucleic acid amplicons
Diagnostics - Fine-needle-aspiration biopsies ease the study of liver lymphocytes
Diagnostics - Lab-on-chip application for DNA detection of sepsis-causing bacteria launched
Diagnostics - Method for quantification of carvedilol in human plasma developed
Diagnostics - Molecular method detects circulating colonic cancer cells in colorectal cancer
Diagnostics - Plasma chemokine levels predict hepatitis C response to antiviral therapy
Diagnostics - Semiconductor developer, Mobidiag introduce lab-on-chip for bacterial diagnosis
Diet & Nutrition - New powder version of dietary supplement introduced
Diet & Nutrition - Treatment center reports dieting can trigger genetically based eating disorders
Disease Associations - Cerebrospinal fluid tau protein studied, diagnostic value indicated
Disease Associations - Hypertension mouse model utilized, cardiac and endothelial events revealed
Disease Associations - Infectious bronchitis virus (IBV) examined, N protein phosphorylation defined
Disease Associations - Vascular smooth muscle cell proliferation studied, inhibition revealed
Disease Associations - Venous thrombosis studied in men, lipoprotein associations revealed
Drug Abuse - Survey conducted by U.S. SAMHSA indicates youth drug use continues to decline
Drug Addiction - Researchers claim one in every hundred Londoners could be crack cocaine users
Drug Delivery - Antibiotic delivery vehicles for musculoskeletal infection treatment studied
Drug Delivery - DelSite files Drug Master File with U.S. FDA for GelSite mucosal applications
Drug Delivery - Furosemide release from ethylene-vinyl acetate matrix characterized
Drug Delivery - Properties of poly(L-lysine iso-phthalamide) copolymers investigated
Drug Delivery - Swiss drug delivery firm licenses diclofenac products to U.S. company
Drug Delivery - Treatment process affects cross-linking of dried paracetamol alginate granules
Drug Delivery - Use of cyclodextrins improves delivery of hydrophobic drugs from hydrogels
Drug Delivery - Wound gel gets regulatory approval to be marketed, sold in Republic of Panama
Drug Development - Demand increases for drugs produced from animal cell cultures
Drug Development - Dermatology drug maker acquires third phase II clinical product
Drug Development - ELISA developed for pharmacological studies targeting HIF-1
Drug Development - First lot of Junovan manufactured to support marketing authorization filing
Drug Development - Intellectual property licensed for MicroRNA gene involved in hepatitis C
Drug Development - New expansion of research collaboration to develop diabetes treatments announced
Drug Development - New repository for annotated electrocardiographic released
Drug Development - New research in the area of drug development detailed
Drug Development - Novel antitrypanosomal agents reviewed
Drug Development - Oral ZD6474 is well-tolerated in patients with advanced cancer
Drug Development - Phase II trial initiated for sterile lidocaine patch
Drug Development - Pivotal phase III trials of Japanese encephalitis vaccine begin
Drug Development - Promising evidence reported for B cell targeted therapies for arthritis
Drug Development - Report indicates growing use of computational biology tools in drug discovery
Drug Development - Review discusses new directions in developing anti-inflammatory, analgetic drugs
Drug Development - Risperdal Consta approved in Italy for treatment of schizophrenia
Drug Development - Rituximab's prior safety experience assumed to be similar in arthritis patients
Drug Development - Safety data from mouse study on drug to treat cancer presented at conference
Drug Development - Small molecule inhibitors of Cdk5-mediated tau phosphorylation identified
Drug Development - U.S. FDA accepts for review NDA for otic solution to treat external otitis
Drug Development - U.S. FDA approves IND for respiratory syncytial virus treatment
Drug Development - U.S. FDA grants Special Protocol Assessment for phase III trials for Miraxion
Drug Development - U.S. FDA grants final approval for Leflunomide for arthritis
Drug Development - U.S. FDA panel recommends approval of Pargluva for type 2 diabetes
Drug Development - Update provided on phase II trial of Indaflex for osteoarthritis of the knee
Drug Development - Zomig proves effective in acute treatment of cluster headache
Drug Interactions - Drug-drug interactions in oncology assessed
Drug Monitoring - Buprenorphine levels in breast milk determined
Drug Research - Cyclooxygenase-2 gene expression inhibited by eugenol-related compounds
Drug Research - Glutathione transferase examined, toxic interactions clarified
Drug Resistance - Drug-resistant genes targeted for inhibition
Drug Resistance - Inhibition of MRP1-mediated efflux pump reversed multidrug resistance
Drug Resistance - Molecular mechanisms for cellular drug resistance identified
Drug Resistance - Multi-drug resistant cells studied, Cl- channel regulation clarified
Drug Resistance - Multidrug resistance-associated protein studied, transport modulation revealed
Drug Safety - New report says counterfeit drug sales to reach $75 billion in 2010
Drug Toxicity - Study examined cardiotoxicity of treatment with capecitabine and oxaliplatin
Echocardiography - Failure of LVEF to increase during DSE identifies risk for late cardiac events
Eczema - Data: Epiceram accelerates skin-barrier recovery
Endocrinology - Diagnosis and treatment of ectopic ACTH secretion discussed
Endocrinology - Findings in endocrinology provide new insights
Endocrinology - Vascular endothelial growth factor responds significantly to hypoglycemia
Environmental Health - Cyanobacterial toxin examined, degradation and detoxification described
Enzymology - Enzyme wanes in peripheral lymphocytes of patients with viral hepatitis
Enzymology - Hepatitis C virus NS2/3 processing is critical for replication
Epidemiology - Asymptomatic malaria underestimates prevalence in endemic areas
Epidemiology - HSV-2 specific serology improves diagnostic accuracy in high prevalent areas
Epilepsy - Computational methods for epileptic seizure detection studied
Epilepsy - NDA submitted to U.S. FDA for antiepileptic drug rufinamide
Esophageal Cancer - Study examining Photofrin photo dynamic therapy with omeprazole data disclosed
Esophageal Candidiasis - Results from phase II trial evaluating antifungal, BAL8557, announced
Fabry Disease - Amigal clinical trial for Fabry disease results released
Facilities - Pharmacy/drug distributor provides update on effect of Hurricane Katrina
Familial Adenomatous Polyposis - Due to COX-2 overexpression, biallelic MYH patients may benefit from NSAIDs
Finance - Biopharma announces common stock offering
Finance - Biopharma company announces revenues of $5.8 million
Finance - Biopharma company reported a net loss of $4.3 million
Finance - Board for growth factor blocker developer approves stock program
Finance - Canadian genomics organizations fund genomics and proteomics projects
Finance - DNA science focused company secures $4M financing commitment
Finance - Dermatology drug maker updates financing commitment
Finance - Diagnostics and therapeutics company completes $10 million private placement
Finance - Drug delivery-focused pharmaceutical company updates '05, '06 financial guidance
Finance - Drug distribution firm completes sale of $900M in senior notes
Finance - Drug-delivery company completes $6.2M series B round
Finance - Evizon maker completes $24.5 million financing
Finance - Genomics-focused company announces $24.5 million direct equity placement
Finance - Grant awarded for commercializing drug infusion system
Finance - Grant awarded for protein bead display method
Finance - Immunotherapy company raises more than $34M in series B financing
Finance - Macromolecular engineered drug maker reports 4Q revenues of $44M
Finance - Microalgae and fungi company announce revenues of $39.5 million
Finance - Molecular cardiology company reports option grants
Finance - Monoclonal antibody focused company files shelf registration statement
Finance - Pharmaceutical distributor reports income of $0.11 per share
Finance - Pharmacy benefit manager announces profit increase of 35%
Finance - Polymer therapeutics developer reports status of cash position
Finance - Protein-based therapeutics maker reports private placement financing
Finance - Relenza maker announces 2005 share purchase plan
Finance - Stem cell technology company reports loss of $0.03 per share
Finance - Stem cell technology firm raises $17.75M in private placements
Finance - Swiss biotech company closes series A financing round with US$21 million
Finance - Testosterone gel maker announces effectiveness of registration statement
Gallbladder Cancer - Intravenous exatecan administered daily to patients with biliary tract cancers
Gastric Cancer - Curcumin affected multidrug resistance in resistant human gastric carcinoma cell
Gastroenteritis - Antibiotic pre-exposure linked to C. jejuni CDT production
Gastroenterology - Brussels team performs first endoluminal fundoplications for GERD patients
Gastroenterology - Survey finds 43% of Americans suffer with common GI disorders
Gene Research - Laser capture microdissection yields insight into angiogenic gene regulation
Gene Therapy - Modified magnetic nanoparticles enhanced gene delivery of HVJ-E vector
Generic Drugs - Pharmaceutical company receives approval to market generic Arava
Generic Drugs - Pharmaceutical products company launches new generic product for infections
Generic Drugs - Tentative approval granted by U.S. FDA for generic Pepcid AC tablets
Generic Drugs - U.S. FDA approval received for generic Glucophage XR Tablets
Generic Drugs - U.S. FDA approves ANDA for generic equivalent of rheumatoid arthritis tablets
Genetics & Genomics - Researchers report details of new studies and findings in the area of genetics & genomics
Genomics - Biosystems company presents data on biomarkers for heart disease, thyroid cancer
Glioblastoma Vaccine Development - Dendritic cell vaccine induces systemic and intracranial responses
Glioma Vaccine Development - Dendritic cell vaccines being developed against intracranial gliomas
Glycemic Control - Insulin infusion better than standard therapy in Saudi children
Glycemic Control - Link between anticoagulation control and glycemic control examined
Growth Disorders - Quality of life instrument developed for adolescent patients
HIV/AIDS Pathogenesis - Reports advance knowledge in HIV/AIDS pathogenesis research
HIV/AIDS Research - Phase 1 clinical findings for HIV entry inhibitor, PRO 140, announced
HIV/AIDS Testing - Immunophenotyping may help with HIV diagnosis in infants
HIV/AIDS Therapy - DSMB recommends continuation of phase II clinical trial of TNX-355 for HIV
HIV/AIDS Therapy - U.S. FDA tentatively approves generic zidovudine oral solution for HIV/AIDS
HIV/AIDS Vaccine Development - HIV-1 env clones developed for vaccine-elicited neutralizing antibody assessment
HIV/AIDS Vaccines - Researchers' work adds to HIV/AIDS vaccines body of knowledge
HIV/AIDS-Associated Dementia - Increased Env compartmentalization in presence of HIV-1-associated dementia
HIV/AIDSTesting - Standards organization gets agreement to improve HIV testing worldwide
Head & Neck Cancers - Head and neck angiosarcomas discussed
Head & Neck Cancers - Lamivudine averts recurrent hepatitis B in patients with nasopharyngeal cancer
Healthcare Coverage - Health plan enters into agreements to distribute Medicare Part D drug plans
Healthcare Coverage - Prescription benefit manager announced additions to consumer-directed plan
Healthcare Coverage - Prescription benefit manager unveils 60-day prescription drug benefit
Hearing Loss - Findings relate aspirin-induced ulcers to hearing loss
Heart Failure - Chronic L-arginine supplementation improves physical function
Heart Failure - Cytokinetics presents data on CK-1827452
Heart Failure - Data analyses can help predict mortality in heart failure patients
Heart Failure - Guidelines cite the use of plasma volume determination
Hematology - Anticoagulants used in treatment of deep vein thrombosis
Hematology - Mast cell activation studied, role of heat shock defined
Heparin - Influence of heparin structure in FGF-2-dependent transformations important
Hepatitis B Virus - Telbivudine has the potential to treat patients with chronic hepatitis B
Hepatitis C Therapy - Hepatitis C genotype 3 infection warrants longer treatment regimens
Hepatitis C Therapy - Virology at 12 weeks marks hepatitis C response to pegylated interferon alpha
Hepatitis C Vaccine Development - Hepatitis C virus-host interactions examined
Hepatitis C Virus - Biotech company announces research collaboration with medical college
Hepatitis C Virus - Pegasys plus Ribavirin awarded priority review status by Japanese agency
Hepatitis C Virus - Renin-angiotensin system polymorphisms are not linked to HCV-related fibrosis
Hepatitis C Virus - Therapy elicits changes in liver metallothionein in chronic hepatitis C
Hepatocellular Cancer - Recent findings in hepatocellular cancer described
Hormone Therapy - Serum levels of C-reactive protein evaluated in response to hormone therapy
Human Papillomavirus Vaccine Development - Assay to quantify antibodies to neutralizing HPV epitopes optimized
Hurricane Relief - Pharmaceutical company aids hurricane relief efforts
Hurricane Relief - Pharmaceutical company announced $1 million donation to Katrina relief efforts
Hypercholesterolemia - Phase I MD-0727 trial initiated for hypercholesterolemia
Hypertension - Bosentan may be well suited for combination therapy with prostanoids
Hypertension - Endothelial fibrinolytic system studied, impairment by cyclic strain defined
Hypertension - Reports advance knowledge in hypertension research
Hypertension - Study compared monotherapies and combination therapies for hypertension
Hypertension - Study examined hemodynamic effects of chronic ETB receptor blockade
Hypertension - Study shows analgesic use does not increase risk of hypertension
Immunology - Botulinum neurotoxin studied, submolecular recognition profiles revealed
Immunology - Model of Waldenstrom macroglobulinemia allows for study of potential therapy
Immunology - Stress augments immunization phase of cell-mediated immunity
Immunology - Study reports on lipoprotein immune responses to spirochetal infection
Immunotherapy - Biotech company presents additional immunotherapeutics study results
Infectious Diseases - $2.7M SBIR fast-track grant awarded trial of antimicrobial catheter system
Infectious Diseases - Antineutrophil cytoplasmic antibody vasculitis associated with infection
Influenza Pandemic - Ethical issues related to preparations for influenza pandemic discussed
Influenza Vaccine - Biopharma company and Wave Biotech partner on influenza vaccine
Influenza Vaccine - Healthcare workers who don't have flu shots could be risking patients' lives
Influenza Vaccine - Patient care team plays role in elderly decisions on influenza vaccine
Influenza Vaccine - Reasons for non-vaccination among healthcare workers explored
Influenza Vaccine - Vaccinating elderly against influenza is cost-effective in Mexico
Influenza Vaccine Development - Influenza vaccination in stem cell transplant recipients examined
Information Technology - InforSense selected by pharma firm for integrative analytics infrastructure
Kidney Transplantation - Tacrolimus safe during statin/calcineurin inhibitor therapy
Leishmaniasis Vaccine Development - Taenia crassiceps glycans act as adjuvant against leishmaniasis
Leishmaniasis Vaccine Development - Antigen expressing epitopes of Leishmania infantum developed
Leucovorin - Recent findings illuminate research in leucovorin
Leukemia - FDA advisory committee recommends accelerated approval of Arranon
Leukemia Vaccine Development - Targeted immunotherapy in acute myeloblastic leukemia reviewed
Leukemia Vaccines - Data advance knowledge in leukemia vaccines research
Liposomal Delivery - Effect of hydrophilic gels on chlorophyllin-loaded liposomes evaluated
Lower Back Pain - Additional phase III placebo-controlled clinical trial of bicifadine launched
Lung Cancer - Apoptosis induced by indirubin-5-nitro-3'-monoxime, a novel CDK inhibitor
Lung Cancer - Asian ethnicity and adenocarcinoma histology predicted response to gefitinib
Lung Cancer - Cisplatin-based chemotherapy used to treat neuroendocrine lung carcinoma
Lung Cancer - Efficacy of intravenous topotecan plus either cisplatin or etoposide evaluated
Lung Cancer - Gemcitabine used in concurrent chemoradiotherapy in stage III NSCLC patients
Lung Cancer - Irinotecan and etoposide used in previously untreated extensive disease SCLC
Lung Cancer - Outcome of pneumonectomies after induction therapy revealed
Lung Cancer - Phase II trial with RFS2000 conducted in NSCLC patients
Lung Cancer - Vinorelbine administered with gemcitabine in previously treated SCLC patients
Lung Cancer Vaccine Development - Targets on small cell lung cancers for immunotherapy identified
Lung Damage - Novel strategy for repairing lung damage detailed in journal
Malaria - International health organization urges responsible use of antimalarial medicine
Malaria - Malaria expert to assist with phase 4 MMH Malarex study
Malaria - Multilocus resistance genotypes highly prevalent in Cambodia
Malaria Diagnosis - Variability of plasmodial PfHRP2 may affect rapid test outcomes
Market Analysis - Increased public awareness raises profile of dietary supplements
Market Analysis - Infertility treatment companies to benefit from untapped European markets
Marketing - New Diabetes Gold sales program launched
Marketing Analysis - The pharma industry's R&D and marketing gap is a big obstacle
Medical Devices - New oral, enteral liquid dispensers launched to increase patient safety
Medical Devices - Study results on implantable device for treatment-resistant depression published
Medical Ethics - Ethical issues from polio eradication programs in India discussed
Medical Ethics - Risk perception and communicable disease vaccines examined
Medicare - Physicians, pharmacists and pharma company form Medicare education coalition
Melanoma - Positive data presented from ongoing phase II immunotherapy study for melanoma
Melanoma - Researchers detail new studies and findings in the area of melanoma
Melanoma Vaccine Development - Anti-self T-cell responses elicited by melanoma antigen characterized
Melanoma Vaccines - New data illuminates research in melanoma vaccines
Meningococcal Vaccine Development - IgG against meningococcal capsular polysaccharide analyzed
Mental Health - Antipsychotics appear to induce changes in calcineurin expression
Mental Health - Cost-effectiveness of depression treatments for underprivileged women analyzed
Mental Health - Data show 900,000 youth planned suicides during major depression
Mergers & Acquisitions - Biopharma company announces closing of collaboration with Biogen
Mergers & Acquisitions - Cyber Group Network acquires veterinary biopharmaceutical firm
Mergers & Acquisitions - Drug-coated medical device maker acquires Afmedica, Inc.
Mergers & Acquisitions - Pharma company completes acquisition of Vicuron Pharmaceuticals
Mergers & Acquisitions - Rice bran company to establishes joint entity with Food Trading Dominicana
Mergers & Acquisitions - Sales, marketing firm acquires Optas to advance pharma relationship marketing
Mergers & Acquisitions - Update provided on impact of Genencor acquisition
Mergers & Acquisitions - Vaccine producer to acquire Cellective Therapeutics, Inc.
Mergers & Acquisitions - Vein disease treatment company to acquire Alabama Vascular & Vein Center
Metastatic Cancer - Brain metastases from epithelial ovarian cancer reviewed
Myelodysplastic Syndromes - U.S. FDA advisory committee recommends Revlimid for full approval
Myeloma Vaccine Development - Tumor antigen immunization of stem cell transplant donors reported
Myocardial Infarction - Data advance knowledge in myocardial infarction research
Myocardial Infarction - Study examined frequency of LV mural thrombus after anterior ST-elevation AMI
Nasal Polyps - Intranasal lysine-aspirin lacks clinical benefit in aspirin-sensitive patients
Natural Products - Jiao Gu Lan extract has bronchodilatory effects
Neospora Vaccine - Response elicited from Neospora caninum tachyzoites characterized
Nephrology - Renal epithelial H+-ATPase studied, targeting role of syntaxin revealed
Neurology - Efficacy of new WHO classification of NETs for selecting treatment examined
Neurology - Nociceptin/orphanin FQ use studied, responses in chicks revealed
Neurology - Researchers' data advance neurology research
Neurology - Retinoic acid signaling analyzed, precursor forebrain populations identified
Neurology - Traumatic brain injury studied, cortical neuron damage clarified
Neuromuscular Disorders - Botulinum neurotoxin type A alters myosin heavy chain composition
Neuroscience - CNS Gly receptors examined, role as cannabinoid targets elucidated
Neuroscience - Clues to Parkinson, Huntington, ALS may be found in gait of affected mice
Neuroscience - Oxidative damage examined, nature of succinate action defined
Neuroscience - Researchers' findings advance neuroscience research
Neuroscience - Tetrahydropapaveroline inhibits dopamine biosynthesis
Neuroscience - Use of abciximab studied in patients with ruptured intracranial aneurysms
Obesity Genomics and Genetics - Genetic modifiers interact with Cpefat to affect weight and adiposity
Obesity and Diabetes - Method to determine insulin resistance in adipose tissue developed
Obstetrics - Women are receiving more pain relief during labor
Oncology - 53BP1 is required for RPA2 hyperphosphorylation following DNA damage
Oncology - Bone marrow micrometastasis lowers breast cancer survival odds
Oncology - Interferon limits genetic instability in livers infected with hepatitis C
Oncology - New oncology training guide released for biopharma sales professionals
Oncology - Novel EGFR inhibitors show promise as PET tumor imaging agents
Oncology - R115777 and paclitaxel overwhelm breast cancer growth and angiogenesis
Oncology - Selective tracer monitors tumors for angiogenesis and metastasis
Oncology - Src boosts angiogenesis and discourages apoptosis in renal cell carcinoma
Oncology - VEGF and its receptor play a role in soft tissue sarcoma aggression
Ophthalmology - Etanercept for refractory ocular sarcoidosis studied in double-blind trial
Orthopedic Surgery - Scientists find way to fight artificial implant infections with antibiotics
Orthopedics - Researchers report details of new studies and findings in the area of orthopedics
Osteoporosis - Bonviva approved for postmenopausal osteoporosis in Switzerland
Osteoporosis - Change in distribution company for Actonel announced
Otorhinolaryngology - Overall survival after cisplatin-radiotherapy compared with radiotherapy alone
Otorhinolaryngology - Treatment options for advanced laryngeal cancer discussed
Ovarian Cancer - Phase Ib clinical trial with PXD101 for ovarian cancer begins
Ovarian Cancer - Recent studies add new data to ovarian cancer research
Pain Management - 5-HT7 receptor examined, localization in dorsal spinal cord discerned
Pain Management - Dexamethasone effective in relieving postoperative pain after tonsillectomy
Pain Management - Opioid tolerance and dependence studied, involvement of compounds revealed
Pain Management - Transdermal fentanyl pharmacokinetics determined in cancer pain patients
Pain Medicine - Chronic sucrose augments mu-opioid discriminative stimulus effects
Pain Medicine - Pharma company provides first clinical test results on NRP290
Pancreatic Cancer - Effects of heavy water on human pancreatic tumor cells examined
Pancreatic Cancer - Induction chemotherapy and concurrent external beam radiation evaluated
Pancreatic Cancer - Panel recommends approval of Tarceva for pancreatic cancer
Pancreatic Cancer - Src is a target for the treatment of pancreatic adenocarcinoma
Pancreatic Cancer Vaccine Development - MUC1 peptide vaccination safe in cancer patients
Parasitology - Inhibition of key enzyme self-association in pathogens assists in treatment
Parkinson Disease - Study demonstrates that rotigotine improves symptoms of early-stage PD
Patents - Buccal drug delivery company receives Canadian patents
Patents - Second patent issued for amino acid platform to formulate challenging drugs
Patents - U.S. patent granted covering drug-eluting stent technology
Patents - U.S. patent granted covering therapeutic products to treat hepatitis B virus
Pediatric Heart Surgery - Chlorhexidine-impregnated dressing prevents CVC colonization
Pediatric Respiratory Distress Syndrome - Gestational dexamethasone dose elicits neurobehavioral abnormalities in rats
Personnel - Anti-infective drug developer announces organizational change
Personnel - Biopharma appoints Allen Shofe vice president of government affairs
Personnel - Biopharma company announces new vice president, human resources
Personnel - Cancer drug developer expands scientific advisory board
Personnel - Chemistry-based drug discovery firm adds three people to management team
Personnel - Christopher Dowd named senior vice president, sales of niche pharmaceutical
Personnel - Contract research company names director market development strategic operations
Personnel - Dermatology company names Rajiv Mathur to board of directors
Personnel - Dr. Khurshid Iqbal joins biopharma CSO
Personnel - Dr. Suhail Nurbhai named vice president, clinical development
Personnel - Drug discovery company announces a new CEO
Personnel - Eric Eisenstadt named VP for research by nonprofit genomics-focused institute
Personnel - Former Lilly executive Gary D. Tollefson appointed to board of biopharm company
Personnel - Karen A. Dawes elected a director of biopharmaceutical company board
Personnel - Michael Astrue named interim CEO of MRI pharmaceutical company
Personnel - Molecular-diagnostics company announces resignation of Aron Braun
Personnel - Neuroscience company elects Michael T. Borer to board of directors
Personnel - Nexium maker appoints Tony Zook as executive VP for North America
Personnel - Oncology drug maker names new members to its board of directors
Personnel - Pancreatic cancer specialist Charles J. Yeo named chair of surgery at Jefferson
Personnel - Pharma company names lead scientist in protein bioanalysis department
Personnel - Pharma company names president and CEO
Personnel - Pharma company nominates new member to its board of directors
Personnel - Plavix maker reports that executive VP, Americas, resigns
Personnel - Principal investigator named for multiple sclerosis drug trial
Personnel - Regenerative medicine-focused company completes executive leadership team
Personnel - Sports nutrition company announces new additions to management
Personnel - Stephen Beckman named VP of sales, marketing by drug development company
Pertussis Vaccine - Action to be taken when facing one or more cases of whooping cough
Pertussis Vaccine - Efficacy of pertussis vaccine in U.S. children examined
Pertussis Vaccine - Variations in B. pertussis isolates in Finland reported
Pharmaceutical Research - Market research firm launches new study on pharmaceutical sales
Pharmaceutical Research - Market research firm releases report on wound, surgical products markets
Pharmaceutical Research - Research firm study examines clinical trial results communication strategies
Pharmacology - Aprepitant can alter warfarin pharmacokinetics and pharmacodynamics
Pharmacology - Dermal permethrin absorption characterized after topical treatment
Philanthropy - Cancer support service offers counseling to patients affected by hurricane
Physiology - Colonic epithelial cells examined, activation of Cl- secretion clarified
Pneumococcal Vaccine - Cost-effectiveness of pneumococcal vaccination for infants reported
Pneumococcal Vaccine - Management of middle ear disease in children with hearing loss outlined
Pneumococcal Vaccine - Tacrolimus ointment does not affect response to pneumococcal vaccine
Polio Vaccine - Dynamic model of poliomyelitis outbreaks developed
Polio Vaccine - Vaccine-associated paralytic poliomyelitis in Brazil examined
Polymorphous Light Eruption - Ethics approval obtained for PMLE trial in Melbourne
Pompe Disease - Trial of Myozyme begins in patients with late-onset Pompe disease
Preventive Medicine - Potential use of statins in treating Alzheimer disease discussed in article
Product Licensing - ImClone Systems licenses UltiMAb Human Antibody Development System
Product Licensing - MCW Research Foundation licenses invention for stroke treatment
Product Licensing - Novartis signs licensing agreement NM1006 treatment for onychomycosis
Product Licensing - Shionogi signs license agreement for HuCAL technology
Prostate Cancer - Calcitriol might enhance effect of taxotere
Prostate Cancer - Clinical development of Teverelix LA on track after pre-IND application meeting
Prostate Cancer - Clinical outcomes of androgen deprivation as sole therapy discussed
Prostate Cancer - Drugmaker to submit BLA to FDA for Provenge for advanced prostate cancer
Prostate Cancer - Local steroid administered during nerve-sparing radical retropubic prostatectomy
Prostate Cancer - Long-term side-effects of intermittent androgen suppression therapy enumerated
Prostate Cancer - Treatments of intermediate-risk prostate carcinoma with radiotherapy reviewed
Prostate Cancer - U.S. FDA responds to SPA for Acapodene for prevention of prostate cancer
Prostate Cancer Vaccine Development - Antibody to PSMA shows promise in androgen-independent prostate cancer
Proteomics - Schizosaccharomyces pombe studied, Na+/H+ exchanger characterized
Proteomics - Ca2+ channels studied, divergent regulation revealed
Proteomics - Cytochrome analyzed, functional role of highly conserved residues defined
Proteomics - Diverse roles of hepatocyte growth factor activator inhibitor type 1 examined
Proteomics - ER-Golgi membrane trafficking studied, role of reticulon defined
Proteomics - Functional of P-glycoprotein in the human blood-placental barrier studied
Proteomics - Neutrophil uptake analyzed, roles of integrin and kinase revealed
Proteomics - Novel antimicrobial peptide studied, role of residues clarified
Proteomics - Novel lipid mediator aspirin-triggered lipoxin A4 induces HO-1 in EC
Proteomics - Plasma membrane protein mobility analyzed, role of lipid interaction revealed
Proteomics - Research in proteomics provides new insights
Proteomics - Somatic angiotensin-converting enzyme studied, negative regulation revealed
Psychiatry - MRI screening can be used to identify organic syndromes
Pulmonary Arterial Hypertension - Interim topline data from STRIDE-2 extension trial announced
Pulmonary Hypertension - Long-term safety profile of bosentan drug in treating PAH confirmed in study
Pulmonary Hypertension - New data illuminates research in pulmonary hypertension
Pulmonary Medicine - Fibroblast growth factor-2 restores pulmonary blood flow in emphysema models
Quality of Life - Adjuvant chemotherapies for colorectal cancer compared
Refractive Surgery - Brimonidine and dapiprazole have similar effects on pupil size
Renal Cancer - Treatment strategies in clear-cell metastatic renal cancer reviewed
Renal Cell Carcinoma - Fluoromisonidazole PET scans assess renal tumor response to hypoxia
Reproduction - Fertilization signaling studied, role of adenylyl cyclase clarified
Reproduction - Laminin analyzed, role in physiology of granulose cells revealed
Respiratory Failure - Feasibility study of Aerosurf complete
Respiratory Medicine - Acute respiratory failure due to Pneumocystis pneumonia observed
Respiratory Syncytial Virus Vaccine - RSV vaccine influences and disease outcome in infected calves
Respiratory Therapy - Study shows COPD patients achieve better lung function with drug combination
Rh Incompatibility - Pregnancy outcome for Rh-alloimmunized women examined
Rheumatoid Arthritis - Generics company has begun shipping Leflunomide Tablets
Rheumatoid Arthritis - Scientist finds new drug effective for rheumatoid arthritis
Rheumatoid Arthritis - U.S. FDA lifts clinical hold on IND for PRTX-100
Rotavirus Epidemiology - Incidence of diarrhea from rotavirus infections in China reported
Rotavirus Vaccine - Burden of rotavirus disease in Malaysia estimated
Rotavirus Vaccine - Incidence of intussusception resulting from RotaShield estimated
Rotavirus Vaccine - Sentinel hospital data for rotavirus diarrhea in Taiwan reported
Rotavirus Vaccine Development - Epidemiological profile of rotaviral infection in India reported
Rotavirus Vaccine Development - Live, attenuated rotavirus vaccine evaluated in Singaporean infants
SARS - Reports advance knowledge in SARS research
SARS Vaccine - Antibodies to SARS-associated coronavirus proteins identified
Schistosomiasis Vaccines - Research add new data to schistosomiasis vaccines body of knowledge
Schizophrenia - NIMH study will guide treatment choices for schizophrenia
Sexual & Reproductive Health - Medication regulation board evaluates use of paroxetine in pregnancy
Sexual & Reproductive Health - U.S. FDA approves ParaGard IUD for women who have not yet had children
Short Stature - Study of new non-growth hormone treatment for short stature underway
Sickle Cell Anemia - Adult sickle cell drug proves effective in young children
Sleep Apnea - Studies on perioperative management of sleep apnea patients are needed
Smallpox Diagnosis - Physicians lack some knowledge about initial presentation of smallpox
Smallpox Vaccine - Humoral antiviral immunity persists within the Japanese population
Spinal Cord Injury - Phase I ProCord study results published in journal
Staphylococcal Infection - Lysostaphin susceptibility assays for S. aureus compared
Statin Therapy - Pravastatin and atorvastatin don't affect bone fracture risk
Statins - Findings describe new data in statins research
Status Epilepticus - Vagal nerve stimulation used to resolve drug allergy-induced SE
Stem Cell Research - Adipose-derived adult stem and regenerative cells hold therapeutic promise
Stem Cell Research - Biotech company discovers another application for its chemokine analog
Stem Cell Research - Immortalized NSCs differ from nonimmortalized cortical neurospheres
Stem Cell Transplantation - Mesenchymal stem cells repair bleomycin-injured lung
Stem Cell Transplantation - Recent findings in stem cell transplantation provide new insights
Streptococcus Vaccine Development - Gene encoding protective antigen of Streptococcus suis identified
Stroke - Stroke association launches "Women In Your Life" education campaign
Subarachnoid Hemorrhage - Clazosentan prevents cerebral vasospasm after aneurysmal SAH
Surgical Devices - Concomitant ablation procedures completed with new system
Surgical Technology - Decellularization may prolong durability of valve allografts
Surgical Technology - Dexamethasone reduces gut permeability in pediatric cardiac surgery
Surgical Technology - Direct decompressive surgical resection used to treat spinal cord compression
Surgical Technology - Liver disease focused company reports room temperature storage results
Surgical Technology - Repair is feasible in patients with small RV and septal defect
Tamoxifen - Researchers publish new studies and findings in the area of tamoxifen
Tardive Dyskinesia - Ebselen attenuates orofacial dyskinesia and oxidative stress in rats
Tetanus Vaccine - Tetanus immune status in plasma donors of Bavarian Red Cross reported
Throat Cancer - Case of hypopharyngeal small cell carcinoma reported
Tissue Engineering - Reports add new data to tissue engineering research
Tobacco Use - Biopharmaceutical company receives grant to fund NicVAX development
Transplant Medicine - Autologous transplantation followed by allogeneic transplantation reported
Transplant Medicine - Belatacept may reduce rate of chronic allograft nephropathy
Transplant Medicine - Studies advance knowledge in transplant medicine research
Trends - Changing priorities to boost IV therapy and enteral nutrition device markets
Tuberculosis - Dutch biotech, Aeras Foundation announce progress in TB vaccine program
Tuberculosis Vaccine Development - DNA vaccine effective in murine model of tuberculosis infection
Tuberculosis Vaccines - Findings advance knowledge in tuberculosis vaccines research
Type 1 Diabetes - Adult stem cell company awarded grant for study of type 1 diabetes
Type 1 Diabetes - Data presented from phase 2 clinical study of inhaled insulin
Type 1 Diabetes - U.S. FDA committee recommends approval of Exubera
Type 2 Diabetes - Data from trial of Actos presented at conference
Type 2 Diabetes - Exenatide diabetes study shows improvements in blood sugar, weight reduction
Type 2 Diabetes - Prosidion presented research data on Dipeptidyl Peptidase IV at conference
Type 2 Diabetes - Research firm reports on vildagliptin and sitagliptin market potential
Type 2 Diabetes - Results from study examining ruboxistaurin mesylate in type 2 diabetes announced
Type 2 Diabetes - Study findings comparing metaglidasen to rosiglitazone released
Type 2 Diabetes - Study suggests chromium picolinate triggers enzyme to improve glucose metabolism
Vaccine Delivery - Biodegradable microparticles to deliver plasmid DNA vaccines produced
Vaccine Delivery - Cholesterol-bile salt vesicles are potential vaccine delivery vehicles
Vaccine Development - Enhanced agonists designed using virtual screening method
Vaccine Development - Killed but active microbes proposed for new vaccine paradigm
Vaccine Efficacy - Exposure to carrier regulates immune responses to conjugate vaccine
Vaccine Efficacy - Measurement of serum bactericidal activity standardized
Vaccine Vectors - Signal in spleen necrosis virus does not allow efficient gene transfer
Vaccines Vector - Findings describe new data in vaccines vector research
Vector Development - Destination vectors for expression screening in E. coli constructed
Vector Development - Nonviral vector for gene delivery and expression in brain developed
Virology - Hepatitis B core promoter mutations intensify liver disease
Virology - Nipah virus studied, endosomal cleavage of fusion protein revealed
Virology - Viral load is valuable for assessing patient response to hepatitis C therapy
Virology Vaccine - DNA vaccine induces specific immune response against hepadnavirus
Weight Gain - Study demonstrates cholesterol-lowering effects of FM-VP4/Statin Zocor combo
Weight Loss - Studies show Advantra Z increases resting metabolic rate
West Syndrome - Efficacy of low-dose ACTH regimens compared
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