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Anti-Infectives

Colistin i.v. effective for control of multiresistant Gram-negative pathogens

Published in Drug Week, October 14th, 2005

Intravenous colistin treatment provides safe and effective control of infections caused by multiresistant Gram-negative pathogens.

"Colistin, an antibiotic almost abandoned for intravenous administration for many years due to its reported toxicity, has been recently reintroduced in clinical practice due to the emergence of multidrug-resistant Gram-negative bacteria and the lack of development of new antibiotics to combat them," physicians in Greece explained.

"To assess the safety and effectiveness of intravenous colistin, in combination with other antimicrobial agents, in the treatment of serious infections in patients without cystic fibrosis, a...

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