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Alzheimer Disease
Nicotinic drugs appear to protect against beta-amyloidosis; further development is indicated
November 18th, 2005
Nicotinic drugs appear to protect against beta-amyloidosis; further development is indicated. "Investigating correlates of tobacco smoking provides the only currently available opportunity of examining effects of long-term exposure of nicotinic receptors on a specific nicotinic agonist in human. Alzheimer-type pathology (A beta and abnormally phosphorylated tau assessed on the basis of AT8 immunoreactivity) together with vascular markers has been compared in age-matched groups of normal elderly smokers and nonsmokers in the entorhinal cortex, an area of noted age-related pathology," scientists writing in the journal Neuropathology and Applied Neurobiology...
Source: Drug Week (2005-11-18)
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