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Analgesia
Ketamine enhances morphine-and-bupivacaine-induced analgesia at {{>=}}20 ng/mL
November 18th, 2005
Ketamine enhances morphine-and-bupivacaine-induced analgesia at level of {{>=}}20 ng/mL. "N-methyl-D-aspartate (NMDA) receptor antagonists enhance opioid-induced analgesia," anesthesiologists in Japan explained. However, the "plasma concentration of ketamine, an NMDA receptor antagonist that enhances epidural morphine-and-bupivacaine-induced analgesia, is not known." To determine the plasma ketamine level associated with enhanced epidural morphine-and-bupivacaine analgesia, M. Suzuki and colleagues at Nippon Medical College "examined 24 patients with lung carcinoma or metastatic lung tumor who underwent video-assisted thoracic surgery in a...
Source: Drug Week (2005-11-18)
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