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Anesthesia
Magnesium sulfate pretreatment attenuates etomidate-induced myoclonus
November 18th, 2005
Magnesium sulfate -- but not ketamine -- pretreatment attenuates etomidate-induced myoclonus. "Myoclonic movements and pain on injection are common problems during induction of anesthesia with etomidate," according to scientists in Turkey, who "investigated the influence of pretreatment with magnesium and two doses of ketamine on the incidence of etomidate-induced myoclonus and pain." "A prospective double-blind study was performed on 100 ASA physical status I-III patients who were randomized into four groups according to the pretreatment drug: ketamine 0.2 mg/kg, ketamine 0.5 mg/kg, magnesium sulfate (Mg) 2.48 mmol, or normal saline," explained A....
Source: Drug Week (2005-11-18)
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