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Angiology
Nitric oxide is critical in maintaining vasodilator tone in the llama fetus
November 18th, 2005
Recent research from Chile has elucidated the role of nitric oxide (NO) during normoxemia and hypoxemia in the llama fetus. "The fetal llama responds to hypoxemia with a marked peripheral vasoconstriction but, unlike the sheep, with little or no increase in cerebral blood flow. We tested the hypothesis that the role of NO may be increased during hypoxemia in this species, to counterbalance a strong vasoconstrictor effect," wrote E.M. Sanhueza and colleagues, University of Chile. "Ten fetal llamas were operated under general anesthesia. Mean arterial pressure (MAP), heart rate, cardiac output, total vascular resistance, blood flows, and vascular...
Source: Drug Week (2005-11-18)
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