Drug Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Drug Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Apoptosis
Arsenic trioxide induces apoptosis in neuroblastoma cell lines
November 18th, 2005
Arsenic trioxide (As2O3) may induce apoptosis in neuroblastoma cell lines. According to recent research from South Korea, "Arsenic trioxide has recently been shown to inhibit growth and induce apoptosis in a variety of hematologic malignancies, but very little is known about its effects on solid tumors and especially on neuroblastoma cells that have self-differentiating characteristics. To demonstrate the growth inhibition induced in neuroblastoma cells (the SH-SY5Y and SK-N-AS cell line) and acute promyelocytic leukemia cells (HL-60) by As2O3, the viable cell numbers were counted after trypan blue staining." "Apoptosis was assessed by the cell...
Source: Drug Week (2005-11-18)
|
