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Adverse Drug Reaction
Male SARS patients have reduced bone mineral density due to prolonged steroid therapy
November 18th, 2005
Male SARS patients have reduced bone mineral density due to prolonged steroid therapy. "During the Severe Acute Respiratory Syndrome (SARS) outbreak in Hong Kong in 2003, patients were treated with very high doses of corticosteroid and ribarivin. The detrimental effects of such treatment on the bone mineral density (BMD) of SARS patients are unknown," researchers in People's Republic of China report. "To compare the BMD of SARS patients with normal range data, a cross-sectional survey was conducted. The bone mineral density of 224 patients with SARS, who were treated with an average of 2753 mg (SD=2152 mg) prednisolone and 29,344 mg (SD=15,849 mg) of...
Source: Drug Week (2005-11-18)
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