Drug Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Drug Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Bacteriology
Kinetics of acute and chronic Brucella infection in mice parallels human infection
November 18th, 2005
Kinetics of acute and chronic Brucella infection in mice parallels human infection. According to a study from the United States, "Despite progress in mouse models of brucellosis, much remains unknown regarding Brucella dissemination and tissue localization. Here, we report the dynamics of Brucella infection in individual mice using bioluminescent Brucella melitensis." "Bioluminescent imaging of infected interferon regulatory factor-1 knockout (IRF-1-/-) mice identified acute infection in many tissues. Brucella was found to replicate in the salivary glands of IRF-1-/- and wild-type C57BL/6 mice...
Source: Drug Week (2005-11-18)
|
