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Biliary Tract Spasm
Hymecromone has bile acid-independent effect on bile secretion
November 18th, 2005
Hymecromone has a bile acid-independent effect on bile secretion. "Hymecromone (4-methyl-umbiliferone) has been used for more than 20 years for the treatment of functional and obstructive spasms of the biliary tract," scientists in Germany explained. "Its mode of action however is still largely unknown," noted R.M. Hoffman and colleagues at Kreiskrankenhaus Gummersbach GmbH, who "investigated the effect of 4-methyl-umbiliferone p.o. and i.v. on gall bladder and common bile duct motility and studied potentially indirect effects via alterations in bile acid metabolism." "Twenty healthy volunteers, aged 25-37 years, 10 males, 10...
Source: Drug Week (2005-11-18)
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