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Age-Related Macular Degeneration

Positive preliminary clinical results presented on EVIZON for treatment of AMD

Published in Drug Week, November 25th, 2005

Genaera Corp. (GENR) announced positive preliminary results from a U.S. phase II clinical trial (MSI-1256F-208) of EVIZON (squalamine lactate) with concomitant photodynamic therapy with Visudyne (PDT) compared to PDT alone in 45 subjects with wet age-related macular degeneration (AMD).

EVIZON with concomitant PDT was well-tolerated in all subjects with no drug-related serious adverse events reported to date. The most common adverse events involved infusion site reactions. These events were generally mild and were distributed evenly across the EVIZON plus PDT treatment groups. Preliminary data were presented for 40 mg or 20 mg of EVIZON with concomitant PDT compared with...

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