Addiction Medicine
Naltrexone pretreatment inhibits meth-induced behavioral sensitization in mice
Published in Drug Week, December 2nd, 2005
"Repeated intermittent exposure to psychostimulants" has been "found to produce behavioral sensitization," researchers in the United States explained.
C.T. Chiu and colleagues at the University of Mississippi Medical Center conducted a study "to establish a mouse model and by which to investigate whether opioidergic system plays a role in methamphetamine-induced behavioral sensitization."
"Mice injected with 2.5 mg/kg of methamphetamine once a day for 7 consecutive days showed behavioral sensitization after challenge with 0.3125...
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Source: Drug Week (2005-12-02)
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