Neuroscience

UCLA scientists use statins to overcome learning disabilities in mice

Published in Drug Week, December 2nd, 2005

In a surprise twist that recalls the film classic "Flowers for Algernon," but adds a happy ending, University of California, Los Angeles (UCLA) scientists used statins, a popular class of cholesterol drugs, to reverse the attention deficits linked to the leading genetic cause of learning disabilities.

The findings are reported in a recent issue of Current Biology; they were studied in mice bred to develop the disease, called neurofibromatosis 1 (NF1).

The results proved so hopeful, that the U.S Food and Drug Administration (FDA) approved the use of the drugs in 3 clinical trials currently under review to test the effect of statins in children...

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Source: Drug Week (2005-12-02)

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