Gastroenterology
Patients with cholangiocarcinomas bear response-predicting gene mutations
Published in Drug Week, December 16th, 2005
According to recent research from South Korea, "epidermal growth factor receptor (EGFR) signalings have recently been implicated in the genesis and progression of cholangiocarcinomas. Thus, the EGFR kinase inhibitor appears to be promising in the treatment of this cancer."
"The response-predicting mutations in the tyrosine kinase domain of EGFR gene have recently been detected in non-small cell lung cancers. This study was, therefore, to investigate if these mutations are also found in cholangiocarcinomas. Twenty-two consecutive cholangiocarcinoma patients who underwent...
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Source: Drug Week (2005-12-16)
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