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Metastatic Melanoma

Phase II study of talabostat in stage IV melanoma complete; results promising

Published in Drug Week, December 16th, 2005

Point Therapeutics, Inc. (POTP) announced results in the company's phase II single-agent study of its oral anticancer drug candidate, talabostat, in patients with stage IV melanoma.

These results were presented in a poster session at the International Society for Biological Therapy of Cancer meeting in Alexandria, Virginia. The company's metastatic melanoma clinical program also includes studying talabostat in a phase II trial in combination with cisplatin.

The single-agent trial included 42 patients with metastatic melanoma, 31 of whom are evaluable for response. Two patients had a response to talabostat as defined by Recist (a 30% or greater...

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