Drug Week
Susan Hasty, Publisher
Table of Contents . . . January 13th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Drug Week | Other Publications
Drug Development - Avelox approved in U.S. to treat complicated intra-abdominal infections
Obesity Therapy - Preliminary results of phase IIb trial of cetilistat in obese diabetic patients announced
Prostate Cancer - Phase III trial's interim analysis shows bone mineral density increased in prostate cancer patients
Stem Cell Research - Experimental Alzheimer, diabetes drug appears to enhance therapeutic effect of cord-blood transplant
ACE Inhibitors - Angiotensin-converting enzyme inhibitors may be linked to weight maintenance in elderly
Acne - Pharmaceutical company begins shipment of generic Adoxa
Acute Lymphoblastic Leukemia - European study confirms efficacy of clofarabine in pediatric patients with ALL
Acute Myeloid Leukemia - Scientists may be able to use novel antibody to target specific cells leading to AML
Acute Myeloid Leukemia - Study of childhood AML yields 1-year survival rates of almost 90%
Acute Peripheral Arterial Occlusion - U.S. FDA specifies protocol for phase III trial of novel arterial perfusion with alfimeprase-3
Cancer Therapy - New research in the area of Cancer Therapy detailed
Adenovirus - Nonhuman adenovirus alters human memory T cells
Adverse Drug Reaction - Agency advises of risk of birth defects with Paxil
Adverse Drug Reaction - Increase in hypothalamic levels of histamine reduces food intake and body weight
Age-Related Macular Degeneration - EMEA to issue updated positive opinion and recommendation of Macugen for AMD
Alcoholism Therapy - Review examines medications for treating alcohol dependence
Allergy & Immunology - Prostaglandin D-2 promotes Th2 cell cytokine release via CRTH2-dependent mechanism
Cancer Therapy - Recent findings in Cancer Therapy provide new insights
Alzheimer Disease - Culprit in Alzheimer disease may have a good side
Alzheimer Disease - First milestone achieved in Alzheimer disease collaboration with Takeda
Alzheimer Disease - Genetic iNOS ablation prevents Alzheimer disease development in mice
Anemia - PBI-1402 phase I trial is complete and shows positive results
Angiography - Power Doppler imaging assesses neoangiogenesis in adult moyamoya disease
Angiology - Findings in angiology provide new insights
Cancer Therapy - Researchers report details of new studies and findings in the area of Cancer Therapy
Angiology - Mechanotransduction drives vascular development
Angiology - Proinsulin C-peptide may control diabetic macroangiopathy
Angiology - Triptans show little effect on diseased epicardial coronary arteries
Anorexia Nervosa - Olanzapine reduces physical activity in hyperactive patients
Anthrax Therapy - Human group IIA phospholipase A2 protects against Bacillus anthracis infection
Anti-Infectives - Research in Anti Infectives provides new insights
Cancer Therapy - Researchers' data advance Cancer Therapy research
Antibiotics - Antibiotics could be withheld in neutropenic cancer patients with fever
Antibiotics - Dutch researchers recommend routine surveillance of antibiotic use and resistance
Antioxidants - Researchers publish new studies and findings in the area of antioxidants
Antisense Technology - Antisense oligonucleotide induces apoptosis and enhances chemosensitivity in prostate cancer cells
Antisense Technology - LIX antisense oligonucleotide therapy reduces murine colitis
Antituberculosis Therapy - Population pharmacokinetics of rifapentine and its metabolite determined in TB patients
Cancer Therapy - Studies add new findings to Cancer Therapy body of knowledge
Apoptosis - Apoptosis induced by folate receptor-mediated delivery of recombinant caspase
Apoptosis - Clonogenic tumor growth inhibited by Smac
Apoptosis - Doxorubicin induces apoptosis in germ line stem cells in the immature testis
Apoptosis - HIN-1 identified as inhibitor of cell growth and invasion
Apoptosis - Ircinin-1 induced apoptosis in human melanoma cells
Apoptosis - L-Ala-induced changes protect pancreatic cells from cytokine-induced apoptosis
Cancer Therapy - Studies advance knowledge in Cancer Therapy research
Attention Deficit Hyperactivity Disorder - ADHD linked with sequence variation in the human dopamine transporter gene
Attention Deficit Hyperactivity Disorder - Pharma company commences manufacturing of patch for ADHD
Autism - New drug-development company with a focus on dysautonomia reports positive meeting with U.S. FDA
Autoimmune Diseases - Cytotoxic antigen induces autoimmune hypophysitis in cancer patients
Autoimmune Diseases - Risk and protective factors revealed for idiopathic inflammatory myopathies
Behavioral Medicine - IDU peers are major source of pressure to engage in high-risk drug preparation practices
Chemotherapy - Researchers provide details of new studies and findings in the area of chemotherapy
Biomedical Engineering - Researchers' work adds to Biomedical Engineering body of knowledge
Bioterrorism - Biodefense program to develop vaccines and treatments for use in biowarfare applications
Bone Density - Drospirenone/estrogen combination is effective in preventing bone loss
Botulinum Toxin - Researchers' findings advance Botulinum Toxin research
Brain Cancer - Plasmalemmal vesicle associated protein-1 highlights brain tumor angiogenesis
Brain Metastases - Analysis finds Efaproxyn extends survival in brain metastases originating from breast cancer
Chemotherapy - Researchers publish new studies and findings in the area of chemotherapy
Brain Tumors - Intensified induction chemotherapy yields positive results in pediatric brain tumors
Breast Cancer - Breast ductal lavage samples bear biomarkers
Breast Cancer - Conjugated linoleic acid may limit VEGF-A expression in breast tumors
Breast Cancer - Data show survival benefit of Arimidex over tamoxifin in early breast cancer
Breast Cancer - Femara shows survival improvement in women with hormone-sensitive early breast cancer
Breast Cancer - Novel group of genes regulates drug susceptibility in breast cancer cells
Drug Resistance - Reports advance knowledge in Drug Resistance research
Breast Cancer - Phase II data on potential new therapy for the treatment of breast cancer announced
Breast Cancer - Reduced dose capecitabine deemed effective treatment in metastatic breast cancer
Breast Cancer - Sentinel lymph node biopsy reduces incidence of lymphedema and erysipelas
Breast Cancer - Studies evaluate impact of switching on survival in adjuvant treatment of early breast cancer
Breast Cancer - Study demonstrates correlation between biomarker reactivity and breast cancer recurrence risk
Breast Cancer - Study shows TC chemotherapy superior to AC in disease-free survival among breast cancer patients
Gynecology - Recent findings in gynecology provide new insights
Breast Cancer - Study shows positive results for dose-dense combination therapy for early-stage breast cancer
Breast Cancer - Symposium highlights that genetic differences may determine breast cancer risk
Breast Cancer - Weekly administration of docetaxel and paclitaxel used to treat breast cancer
Breast Cancer Therapy - Report describes side effects observed with cancer risk reduction for tamoxifen
Business & Finance - Biologics maker announces filing of application to appoint receiver and resignation of directors
Business & Finance - Hepatitis drug developer sharpens focus on key development programs
HIV/AIDS Vaccines - New findings in HIV/AIDS Vaccines described
Business & Finance - Investrend Research initiates coverage of company acquiring Cryobanks International, Inc.
Business & Finance - Research note issued on Callisto Pharmaceuticals
Business & Finance - orBec maker receives extension to comply with AMEX listing standards
Business Update - Ophthalmic pharmaceutical maker announces U.S. FDA inspection results
Business Update - Vasovist maker to reduce workforce
COX-2 Inhibitors - COX-2 inhibitors may disrupt inflammatory PG balance, resulting in reported adverse effects
Oncology - Researchers provide details of new studies and findings in the area of oncology
Cancer Gene Research - Arrayed primer extension detects breast and ovarian carcinoma mutants
Cancer Gene Therapy - Combinatorial antiangiogenic gene therapy regresses tumors in glioblastoma
Cancer Gene Therapy - E2F-1 gene therapy up-regulates PKR and inhibits growth of leiomyosarcoma
Cancer Gene Therapy - PKR-induced mammalian cell death tested in an antisense cellular screening assay
Cancer Gene Therapy - Tropism expanded in a human adenoviral vector with a chimeric fiber
Cancer Research - Phase III data show Aranesp increases and maintains patient hemoglobin levels
Oncology - Researchers publish new studies and findings in the area of oncology
Cancer Therapy - Advances in radiotherapy show benefit for elderly patients with leukemia and non-Hodgkin lymphoma
Cancer Therapy - Affymax, partner present preclinical data for novel angiogenesis inhibitors
Cancer Therapy - Angiotensin II receptor blockers staunch prostate cancer proliferation
Cancer Therapy - Brain cancer treatment approved in Scotland but still not available to all in U.K.
Cancer Therapy - CTLA-4 provides a potential target for antitumor therapeutic intervention
Cancer Therapy - Chemotherapy and resection therapy clarified in anaplastic oligodendroglioma
Oncology - Studies add new findings to oncology body of knowledge
Cancer Therapy - Data supports potential clinical utility of GRN163L in patients with multiple myeloma
Cancer Therapy - Drug-development company starts clinical trial with PHP in first-line extension
Cancer Therapy - Dual integrin antagonist elicits antiangiogenic activity
Cancer Therapy - Enzyme inhibitor limits radiation-induced tumor angiogenesis and invasion
Cancer Therapy - Extracellular matrix adherence linked to suppression of peritoneal implantation
Cancer Therapy - Findings in Cancer Therapy provide new insights
Oncology - Studies advance knowledge in oncology research
Cancer Therapy - Glioma cell growth inhibited by siRNA targeting of growth factor
Cancer Therapy - HGS-ETR2 is well tolerated in patients with advanced solid tumors
Cancer Therapy - Hematologic safety and tolerability of topotecan investigated
Cancer Therapy - Mechanism of an anticancer lysophospholipid described
Cancer Therapy - Nonsteroidal anti-inflammatory drugs marked for development into anticancer agents
Proteomics - Researchers' work adds to proteomics body of knowledge
Cancer Therapy - O-6-benzylguanine and temozolomide used to treat pediatric patients with solid tumors
Cancer Therapy - Optimum management of patients with low-grade gliomas investigated
Cancer Therapy - Oral temozolomide used for heavily pre-treated brain metastases
Cancer Therapy - Phase II study of oregovomab for recurrent ovarian cancer indicates further study is warranted
Cancer Therapy - Positive AT-101 data presented in four posters at hematology meeting
Cancer Therapy - Positive PXD101 phase I results presented at the American Society of Hematology
Transplant Medicine - New research in the area of Transplant Medicine detailed
Cancer Therapy - Primary tumor of pancreatic cancer measured in chemotherapy trials
Cancer Therapy - Quadramet/ bortezomib combo demonstrates broad anticancer activity in preclinical study
Cancer Therapy - Radioiodine tracks the pharmacokinetics of angiostatin
Transplant Medicine - Researchers detail new studies and findings in the area of Transplant Medicine
Cancer Therapy - Results reported of Phase II interleukin-2, granulocyte-macrophage colony-stimulating study
Cancer Therapy - Use of agarose capsules chemotherapeutically targets tumors
Cancer Vaccine - Psidium guajava extracts exert antitumor effect
Cancer Vaccine - Herpes simplex virus type-1 amplicons linked to vaccine generation in lymphoblastic leukemia
Cancer Vaccine - Neutralizing intrabodies against Etk kinase impair cellular transformation
Cardiology - Cardiac endothelial cells express multiple variants of neuregulin-1
Cardiology - New findings in the area of cardiology described
Cardiovascular Disease - HDL-C is a key predictor of risk and treatment benefit in people over 70
Cardiovascular Disease - No significant benefit to early catheterization was found
Cardiovascular Disease - Selective aldosterone antagonist without side effects is next step in BP control
Cardiovascular Disease - Task force supports more intensive LDL-cholesterol lowering
Cardiovascular Research - 17-Beta-estradiol reduces oxidative stress, cardiac injury in rat study
Cardiovascular Research - Hyperhomocysteinemia is a weak prothrombotic factor
Cardiovascular Research - Local delivery of 17 beta-estradiol improves vascular healing
Cell Biology - Cell migration is induced by nucleotide receptor interaction with integrins
Cell Biology - Lipid rafts take aminoacyl-tRNA synthetase subunit p43 into endothelial cells
Cell Biology - Notch signals help hypoxia maintain undifferentiated cells
Cell Biology - Novel approach facilitates quantification of gap junction selectivity
Cervical Dystonia - BoNTA, a serotype of botulinum toxin, has fewer side effects and a longer duration of effect than BoNTB
Chemotherapy - New data illuminates research in chemotherapy
Chemotherapy - Potential signal for arrhythmias and cardiac arrest are found with dolasetron
Chemotherapy - Squamous and nonsquamous cancers respond alike to platinum-based combination chemotherapy
Childhood Obesity - Report reviews pharmacotherapy of childhood and adolescent obesity
Cholestasis - Flucloxacillin treatment results in the formation of hepatic protein adducts
Chronic Lymphocytic Leukemia - Drug for lymphocytic leukemia shown to be generally well tolerated and biologically active
Chronic Lymphocytic Leukemia - Phase II talabostat plus rituximab trial exceeds targeted 20% response rate in CLL patients
Clinical Trials - Centocor Research & Development expands relationship with drugmaker
Clinical Trials - Enrollment of 13,800 patients completed in global trial of Angiox (bivalirudin)
Clinical Trials - Integrin antagonist MEDI-522 may impede tumor angiogenesis
Clinical Trials - Paper recommends internationalization and education as keys to clinical trial recruitment
Clinical Trials - Ritalin can be effective for control of hyperactivity
Clinical Trials - Study reviews published strategies to enhance treatment fidelity of health behavior interventions
Clinical Trials - Third PMA module submitted to the U.S. Food & Drug Administration for Oxiplex/SP Gel
Collaborations - BioFocus division extends its collaboration with Amgen throughout 2006
Collaborations - Clinical trial alliance focuses on reducing the side effects of chemotherapy drugs
Collaborations - Deal with Bristol-Myers Squibb Company expanded for the discovery of kinase inhibitors
Collaborations - European marketing agreement signed for Sativex
Collaborations - Infectious disease-focused company signs third deal for biopharmaceutical manufacturing
Collaborations - Joint venture formed to make sterile-filled injectable drugs in New York
Collaborations - Late stage licensing agreement signed for anti-sepsis drug CytoFab
Collaborations - Partners revise agreement for development, commercialization of Glumetza
Collaborations - Partnership combines human antibody therapeutic pipelines
Collaborations - Roche and Swiss systems biology initiative collaborate on type 2 diabetes research
Collaborations - Roche files IND with U.S. FDA for antibody developed under collaboration
Collaborations - VipMedRx selects company for electronic prescription fulfillment
Collagen - Elongated collagen domain induces differentiation in fibroblasts
Colon Cancer - Galectin-3 modulates MUC2 mucin expression in human colon cancer cells
Colon Cancer - Immunity induced by injection of dendritic cells expressing interleukin-15
Colon Cancer - Retinol inhibited growth of colon cancer cells
Colon Cancer Vaccine - Epitope-specific immunization inhibits epidermal growth factor receptor signaling
Colorectal Cancer - Major hepatectomy for colorectal cancer metastasis improved survival in elderly
Colorectal Cancer - Prognostic and predictive significance of the p53 mutation assessed
Colorectal Cancer - Two new clinical sites added for colorectal drug trial in Israel
Complementary & Alternative Medicine - Aqueous extract from dried immature hardy orange has selective prokinetic activity
Complementary & Alternative Medicine - Herbal agent overwhelms glioma proliferation
Consumer Protection - Agency acts to protect public from fraudulent avian flu therapies
Contraception - Intrauterine system provides effective contraception during lactation
Contraception - Oral contraceptive drospirenone may provide some cardiovascular risk reduction
Corporate Update - Functional genomics-focused company realigns to move closer to customers
Critical Care Medicine - Thorough understanding needed to manage hyperannomenia in UCD
Crohn Disease - Crohn disease patients with Nod2/CARD15 gene variants require early surgery
Cytomegalovirus - Adeno-associated virus type-2 infection reduces the grafted cell survival
DNA Damage - Jun activation domain-binding protein required for mitotic checkpoint activation
Depression - Study shows Cymbalta reduces depression symptoms at least as fast as Lexapro
Dermatology - Air-cooling the skin reduces the pain of photothermolysis treatment
Diabetes Complications - High tumor necrosis factor alpha levels may cause endothelial dysfunction in diabetic patients
Diabetes Complications - Thromboxane A2 receptor antagonist prevents atherogenesis caused by diabetes mellitus
Diabetes Complications - Vascular endothelial growth factor isoform imbalance occurs in diabetic retinopathy
Diabetes Pathogenesis - Adiponectin receptor 1 gene polymorphisms are linked to insulin resistance and liver fat
Diabetes Pathogenesis - GLP-1 metabolite improves left ventricular performance in dogs with DCM
Diabetes Pathogenesis - Renal cortex of streptozotocin-induced diabetic rats has lower nitric oxide levels
Diabetes Pathogenesis - Th1 cell response for Hsp60 AA437-460 is more prominent in type 1 diabetes patients
Diabetes Therapy - Diabetes makeover program continues to yield positive results
Diabetes Therapy - Extracts of Piper betle leaves possess safe and strong antidiabetic activity
Diabetes Therapy - Muraglitazar increases risk of death and cardiovascular events in type 2 diabetes
Diabetes Therapy - Oral administration of stevioside improves insulin sensitivity
Diabetes Therapy - Potential of sodium glucose cotransporter 2 inhibitors as antidiabetic agents is assessed
Diagnostics - Diagnostics company announces gene-based assay to ID cancers of unknown primary origin
Diagnostics - Diagnostics company presents data on soon-to-be introduced assay for hematologic diseases
Diagnostics - Rapid assay detects fibroblast growth factor receptor 3 mutations in bladder cancer and urine
Diagnostics - Research in diagnostics provides new insights
Diet & Nutrition - Argan oil consumption may have antiatherogenic effect
Diet & Nutrition - Dietary quercetin may protect against effects of environmental endocrine disrupters
Diet & Nutrition - NF-kappa B activation mediates hepatic inflammation in steatohepatitis model
Diet & Nutrition - Therapeutic use of cannabinoide agonists and antagonists proposed to treat eating disorder
Distribution Agreement - Dental products company secures exclusive U.S. distribution rights for drug for aphthous ulcers
Drug Abuse - ADH4 gene variation is associated with alcohol and drug dependence
Drug Abuse - Buprenorphine, methadone are equally effective in producing reinforcing and subjective effects
Drug Abuse - Study suggests that hormonal state modulates drug craving
Drug Delivery - High bioavailability reported for sustained-release gastroretentive formula of ofloxacin
Drug Delivery - MPEG-PLGA diblock copolymer implantable wafers show promise for protein delivery
Drug Delivery - Recent findings illuminate research in Drug Delivery
Drug Delivery - Research reveals possibility for enhanced transmucosal delivery of peptides and proteins
Drug Delivery - Usnic acid-loaded nanocapsules suitable for use in in vivo studies
Drug Development - 1,4-DHP derivative promotes DNA repair in cultured human cells
Drug Development - AMN107 can produce dramatic benefits in some forms of leukemia resistant to Gleevec
Drug Development - Antitubercular purines have low toxicity toward mammalian cells
Drug Development - Approval granted for Retaane suspension in Australia
Drug Development - Eculizumab shows sustained improvements in hemolysis, transfusions in patients with PNH
Drug Development - European phase III trial for Miraxion in Huntington disease commences
Drug Development - Farnesyltransferase inhibitor ABT-100 abates angiogenesis
Drug Development - GSK selects development candidate directed to second mitotic kinesin target
Drug Development - Isoflavones have anticoccidial activity
Drug Development - Isoform-selective retinoic acid receptor agonists discovered
Drug Development - Marketing approval granted for generic versions of lansoprazole in the U.K.
Drug Development - N-acylethanolamines and other antimitotic agents evaluated as possible inductors of apoptosis
Drug Development - National Cooperative Drug Discovery Group names pharma company as corporate partner
Drug Development - Novel diaroylhydrazine ligands show promise as iron chelators
Drug Development - Oral toll-like receptor ligand chosen as next drug development candidate for cancer
Drug Development - Patient randomization target exceeded for completion of North American Itax phase III trial
Drug Development - Phase I study to evaluate ALN-RSV01 for the treatment of respiratory syncytial virus
Drug Development - Phase I trial for Imprime PGGTM cancer therapy initiated
Drug Development - Phase III trial of Anturol oxybutynin gel for overactive bladder to be initiated in early 2006
Drug Development - Plasminogen kringle 5 deletion mutant may control pathological angiogenesis
Drug Development - Proteasome inhibitors evaluated in lymphoid malignancies
Drug Development - Researchers have developed a screening method for isomeric mixtures of aziridines
Drug Development - Second clinical trial for bone fractures therapy initiated in Spain
Drug Development - Suppression of glutamate release may underlie effects of agmatine
Drug Development - Synthesis and biological evaluation of polyhydroxycurcuminoids described
Drug Development - Synthetic vascular endothelial growth factor receptor binding antagonist may fight cancer
Drug Development - Trial to study effect of Agilect in slowing progression of Parkinson disease
Drug Development - U.S. FDA approval granted for Carbamazepine tablets USP as anticonvulsant
Drug Development - U.S. FDA approval granted for generic version of OxyContin in three strengths
Drug Development - U.S. FDA grants approval for Azithromycin for injection
Drug Development - U.S. FDA issues approvable letter for Diquafosol
Drug Devleopment - Integrin-linked kinase blockade targets signals linked to glioblastoma progression
Drug Discovery - Drugmaker announces discovery of potent inhibitors of SirT1
Drug Resistance - Data advance knowledge in Drug Resistance research
Drug Resistance - Emerging resistance in foodborne pathogens increase burdens of illness and outbreaks
Drug Resistance - Oral VEGF receptor inhibitor YM-231146 beats paclitaxel resistant tumors
Embryonic Development - Antagonistic interaction signaling occurs in the Xenopus embryo
Encephalitis - Gene expression examined during infection with West Nile virus strains of different neurovirulence
End-of-Life Issues - Caregivers perceive the need greater access to ICU treatment and bioethics for end-of-life care
Endocrinology - Researchers' data advance endocrinology research
Endotoxic Shock - Oral geranylgeranylacetone pretreatment improves rat survival after LPS injection
Epidemiology - Dental health disparities among Israeli 12-year-olds reported
Epilepsy - Treatment for refractory partial seizure disorder is costly
Erectile Dysfunction - A severe, undiagnosed disease can be the cause of erectile dysfunction
Esophageal Cancer - Basic fibroblast growth factor risk for esophageal cancer is ameliorated
Esophageal Cancer - Neoadjuvant therapy advised only in centers with maximum surgical expertise
Facilities - Pharmacy benefit manager announces that its third operational facility is now open in Georgia
Fanconi Anemia - Assay established for complement assignments in FA patients
Feline Immunodeficiency Virus Therapy - Neutralizing Abs inactivate rHuG-CSF in FIV-infected cats on long-term therapy
Finance - Biopharma company announces net loss of $4,571,000
Finance - Biopharma company secures $34.2 million financing in 2005
Finance - Biopharma company to raise $13.3 million through sale of common stock and warrants
Finance - Biotech company announces CAN$16.48 million private placement
Finance - Canadian biopharmaceutical firm completes private financing
Finance - Cancer drug developer announces $30M common stock offering
Finance - Cancer drug developer establishes American Depositary Receipt program
Finance - Cell therapy report added to Research & Markets' offerings
Finance - Chinese pharmaceutical firm reports options to trade on Chicago Board Options Exchange
Finance - Cord stem cell bank company highlights strategic initiatives
Finance - Dermatology-focused pharma amends terms of series D cumulative convertible preferred stock
Finance - Gates Foundation $30M grant to be used to reduce morbidity and mortality from parasitic disease
Finance - Generic pharmaceutical firm's chairman, CEO files to exercise options for common shares
Finance - Hematology-focused biotech company obtains receipts for short-form prospectus
Finance - Hematology-focused company closes offering for proceeds of $34,500,000
Finance - Human domain antibody company raises $29 million in series B financing
Finance - OxyAlert maker receives new symbol with reverse stock split
Finance - Oxygen therapeutics developer reports loss of $0.34 per share
Finance - Pharma company increases dividend 26% to 24 cents per share for the first quarter of 2006
Finance - Respiratory disorders-focused company prices secondary offering
Finance - Retail drug company announces revenues increased 0.9% in the third quarter
Finance - Specialty pharma company reports net loss of $2.6 million
Finance - Ultrasound company secures $24 million in series B financing
Fungal Infections - Study shows Noxafil reduces invasive fungal infections in high-risk chemotherapy patients
Gastroenterology - Findings describe new data in gastroenterology research
Gastroenterology - Macrophage migration inhibitory factor supports intestinal tumorigenesis
Gastroenterology - Monocyte chemoattractant protein-1 boosts angiogenesis in gastric cancers
Gene Expression - Gene expression cascades influence valproic acid-induced skeletal malformations
Gene Research - Coronary microvascular endothelial cell growth regulates gene expression
Gene Therapy - Retroviral suicide gene therapy achieves long-term survival in glioma
Gene Therapy - Ribozyme-mediated targeted replacement specifically regresses human cancer cells
Generic Drugs - Pharma company receives U.S. FDA approval for Cefprozil Tablets
Genetics & Genomics - B-catenin signaling negatively regulates retinal-neurite extension
Genetics & Genomics - Interplay occurs in IFN-gamma-inducible MHC-II gene expression
Genetics & Genomics - Null alleles identify familial hypercholesterolemia patients
Genetics & Genomics - Nutritional genomics may benefit public and personal health
Glioblastoma - Response of glioblastomas to EGFR kinase inhibitors linked to molecular determinants
Glioblastoma Multiforme - Trial of glioblastoma multiforme treatment reaches intent-to-treat patient enrollment milestone
Gynecology - Recent findings in gynecology described
HIV/AIDS Adverse Drug Reaction - CNS toxicity associated with increased efavirenz plasma levels in HIV/AIDS
HIV/AIDS Drug Adherence - Pediatric HAART adherence positively impacted by commitment of mother to adherence
HIV/AIDS Drug Adherence - Researchers detail new studies and findings in the area of HIV/AIDS Drug Adherence
HIV/AIDS Drug Adherence - Variations in patterns of HAART adherence associated with behavior and age
HIV/AIDS Drug Development - Indolyl aryl sulfone NNRTIs inhibit drug-resistant RT mutants via selective targeting
HIV/AIDS Drug Resistance - Genetic variants may predict virologic failure and/or emergence of drug-resistant HIV
HIV/AIDS HAART - Antiretroviral combinations results in high nonresponse rate in HAART-naive patient
HIV/AIDS HAART - HAART associated with life-threatening maternal and fetal macrocytic anemia
HIV/AIDS HAART - Researchers report details of new studies and findings in the area of HIV/AIDS HAART
HIV/AIDS Pathogenesis - Studies add new findings to HIV/AIDS Pathogenesis body of knowledge
HIV/AIDS Therapeutic Monitoring - IGF-I levels indicate HAART efficacy and can be used to monitor compliance
HIV/AIDS Therapy - Cell cycle arrest induces a decrease in HIV susceptibility to nucleoside analogues
HIV/AIDS Therapy - Functional immunity in HIV/AIDS may be reconstituted with partially suppressive HAART
HIV/AIDS Therapy - Inhibition of CTL function by immunosuppressive therapy may enhance HIV-1 replication
HIV/AIDS Therapy - Interleukin-7 is a potential therapy for HIV-1-infected individuals
HIV/AIDS Transmission - Human beta-defensins suppress HIV-1 infection
HIV/AIDS Vaccines - Findings describe new data in HIV/AIDS Vaccines research
HIV/AIDS-Related Infection - Paracoccidioidomycosis behaves as opportunistic infection when associated with HIV
HIV/Tuberculosis Coinfection - HIV-1 replication persists despite treatment of pulmonary TB in coinfected patients
HIV/Tuberculosis Coinfection - Low maximum rifampin and ethambutol concentrations common in HIV/TB coinfected patients
Head & Neck Cancer - Appearance of necrosis in head and neck cancer patients indicates need for cure
Head & Neck Cancer - Protease inhibitor ritonavir augments radiotherapy in cancer models
Healthcare Access - U.S. alliance forms to address healthcare disparities between blacks and whites
Healthcare Costs - Cost of intraperitoneal chemohyperthermia and cytoreductive surgery estimated
Healthcare Costs - Expanding public healthcare is a great burden on the tax system
Healthcare Costs - Itraconazole more cost effective than amphotericin B for systemic fungal infections
Healthcare Coverage - Premera Blue Cross Score Card shows improvement in diabetics' disease control
Helicobacter pylori - H. pylori eradication results in complete histological remission of MALT lymphoma
Hematology - Amifostine cuts vascular endothelial growth factor secretion in hemopoietic stem cells
Hematology - Studies suggest red blood cell transfusions may be unnecessary for all heart surgeries
Hemophilia - Study of Factor VIII demonstrates efficacy to prevent joint bleeding in hemophiliacs
Hepatitis B Virus - HBV sequence analysis compared with INNO-LiPA HBV DR line probe assay
Hepatitis B Virus - Hepatitis B virus YMDD motif variants genotyped by an improved dot blot method
Hepatitis B Virus - Hepatitis B virus surface antigen characterized from a recombinant cell line
Hepatitis B Virus - New data illuminates research in Hepatitis B Virus
Hepatitis C Therapy - Research shows novel polymerase and protease inhibitors may revolutionize hepatitis C treatment
Hepatitis C Virus - Non-nucleoside inhibitors characterized for hepatitis C virus NS5B polymerase
Hepatitis C Virus - Recent studies add new data to Hepatitis C Virus research
Hepatitis C Virus Therapy - Anti-hepatitis C virus effects of interferon and ribavirin detected
Hepatitis C Virus Therapy - HCV cirrhotic patients safely treated after partial splenic embolization
Hepatitis Therapy - Concanavalin A-induced hepatitis is inhibited by a multiple cytokine modulator
Hepatocellular Cancer - An oncofetal protein functions as a marker for hepatocellular carcinoma
Hepatocellular Cancer - Cetuximab alone or in combination therapy fights liver cancer
Hepatocellular Cancer - Hepatocellular carcinoma curbed by universal HBV vaccination
Hepatocellular Cancer - Laminin-5 induces cell transition in hepatocellular carcinoma
Hormone Replacement Therapy - Action of hormone replacement therapy on insulin secretion merits further study
Hormone Therapy - Transdermal progesterone cream was preferred over oral medroxyprogesterone acetate
Huntington Disease - Cell model provides screen for potential Huntington disease therapeutic compounds
Hypertension - Howard University Hospital acquires BVA-100 blood volume analyzer
Hypoxia - STAT3 activation powers peroxynitrite-induced vascular endothelial growth factor
IGF-1 Deficiency - U.S. FDA approves IPLEX for the treatment of severe primary IGF-1 deficiency
Idiopathic Pulmonary Fibrosis - Use of interferon gamma-1b recommended for patients with progressive IPF
Imaging - Imaging of prostate cancer achieved using adenovirus-expressed symporter
Imaging - Transplanted living functional cells noninvasively imaged
Immune Function - Protein, iron, and zinc intake enhance immune function in older women
Infectious Disease - Rotavirus vaccine gets positive opinion from European regulatory authorities
Infectious Diseases - New fight against polio launched in Indonesia
Infectious Diseases - Research to improve understanding of Lyme and other tick-borne diseases
Inflammatory Disease - Anti-inflammatory agent, Elafin, successfully completes phase I clinical trial.
Influenza - CAIV-T data show 55% reduction in influenza illness compared to injectable influenza vaccine
Influenza - Initial federal funding obtained to develop RNAi therapeutics for pandemic influenza
Influenza Pandemic - Use of antiviral agents is recommended in influenza pandemic
Informatics - Drug-discovery company licenses target informatics platform to AstraZeneca
Information Technology - Novartis Farmaceutica selects online training program
Insomnia - Phase II human testing clinical trial commences for insomnia drug
Intracerebral Hemorrhage - Collaboration to codevelop recombinant factor VIIa therapeutics for acute bleeding
Intracerebral Hemorrhage - Rapid antifibrinolytic treatment with strict blood pressure control reduces hematoma growth risk
Invasive Aspergillosis - PCR-ELISA more sensitive/reliable than real-time PCR for invasive aspergillosis diagnosis
Irritable Bowel Syndrome - Phase III study of PTI-901 shows favorable safety profile but did not meet primary endpoint
Ischemic Stroke - Phase III SAINT II trial for NXY-059/Cerovive will continue as planned following safety review
Legal Issues - Federal agency acts to seize ephedra-containing dietary supplements
Leukemia - Cladribine used to treat hairy cell leukemia
Leukemia - Dacogen injection resubmission accepted for review by U.S. FDA
Leukemia - Preclinical studies of GX15-070 show it induces apoptosis in several types of blood cancers
Lipid Research - Amphotericin B lipid complex effective in HCT recipients with invasive aspergillosis
Liver Cancer - Adjuvant interventional treatments may help the bridge to liver transplantation
Liver Cancer - Recent findings in Liver Cancer provide new insights
Liver Failure - Transplantation and/or ganciclovir therapy restores function after liver failure
Liver Regeneration - PFT induced p53 inhibition does not affect liver regeneration after partial hepatectomy
Liver Transplant - Liver transplantation for hepatocellular carcinoma discussed
Lung Cancer - Concurrent chemoradiotherapy with gemcitabine improved outcomes in lung cancer
Lung Cancer - Gemcitabine and carboplatin used to treat non-small cell lung cancer
Lung Cancer - Improvements in curative treatment of non-small-cell lung cancer being sought
Lung Cancer - New treatment strategies for lung cancer that reduce associated costs are needed
Lung Cancer - Paclitaxel/carboplatin/etoposide compared to paclitaxel/topotecan
Lung Cancer - Pemetrexed used to treat non-small cell lung cancer
Lung Cancer - Radical lung resection advised for select, non-small cell lung cancer patients
Lung Cancer - Role of pemetrexed in treatment of small-cell lung cancer evaluated
Lung Disease - Inflammatory lung disease therapy must be carried out using oxidation-resistant variants
Lymphangioma - Angiogenic mediators encourage benign cervicofacial tumor progression
Lymphatic Metastasis - Hyperfibrinogenemia used to predict lymphatic metastasis in human gastric cancer
Lymphocytic Leukemia - Lymphocytic leukemia study shows survival benefit of up to 31 months after MabCampath treatment
Lymphoma - Biologic agent may improve efficacy of rituximab in relapsed follicular lymphoma
Lymphoma - Central nervous system prophylaxis should be used in sinonasal lymphoma
Lymphoma - Patients may benefit from earlier radioimmunotherapy for refractory and hard-to-treat cancers
Malaria Therapy - Plasmodium falciparum's separate organelle-specific pathways are both potential targets for drug development
Market Analysis - Antibacterial resistance is driving the need for the next generation of antibiotics
Market Analysis - Change in patent status has not affected Taq brand preferences
Market Analysis - Several promising agents for idiopathic pulmonary fibrosis are now in clinical trials
Marketing - New report shows early drug pricing analysis can help products win favorable reimbursement status
Medical Devices - InDuo is as effective as HumaPen Ergo and Accu-Chek Sensor Meter for insulin and BG control
Medical Devices - New portable inhalation device available for Ventavis patients
Medicare - Cigna and Longs Drugs team up to comarket Cignature Rx Medicare prescription drug plan
Medicare - Medicare coverage announced for Baha Hearing System
Medicare - New tool allows seniors to research Canadian drug costs versus Medicare D
Melanoma - Pegylated arginine deiminase used to treat patients with metastatic melanoma
Mental Health - Bipolar disorder facts discussed following the Miami Airport incident
Mental Health - Long-term peyote use doesn't affect psychological or cognitive performance in Native Americans
Mental Health - Rapid quetiapine titration feasible in combination with mood stabilizer treatment
Mergers & Acquisitions - Biotech company broadens diabetes pipeline with acquisition of Nurel Therapeutics
Mergers & Acquisitions - Biotech company to acquire Abgenix for $22.50 per share
Mergers & Acquisitions - Breast implant maker's board determines Allergan transaction is fair and superior to Medicis offer
Mergers & Acquisitions - Cyclacel and immune-focused company join forces to create international biopharmaceutical company
Mergers & Acquisitions - Dermatology company to acquire SansRosa Pharmaceutical Development, Inc.
Mergers & Acquisitions - GlaxoSmithKline closes acquisition of vaccine developer
Mergers & Acquisitions - INC Research acquires contract research organization
Mergers & Acquisitions - Metaphore Pharmaceuticals, Inc. to be acquired by antibacterial-focused company
Mergers & Acquisitions - Tissue-engineered therapeutics company executes letter of intent to acquire Hapto Biotech
Mesothelioma - Pemetrexed and cisplatin considered standard therapy for malignant pleural mesothelioma
Methicillin-Resistant Staphylococcus Aureus - Staphylococcus aureus in thermal injury is controlled via effector cell induction
Multiple Myeloma - Aplidin phase II trial reaches objective of overall response rate in patients with multiple myeloma
Multiple Myeloma - CD52 is not a promising target for antibody-based therapies for most patients with multiple myeloma
Multiple Myeloma - Resveratrol inhibits myeloma cell growth and promotes osteoclast differentiation
Multiple Myeloma - Velcade trial demonstrates a 6-month survival advantage for multiple myeloma patients
Multiple Sclerosis - EBV and HHV-6B co-expression in MS is associated with disease activity
Multiple Sclerosis - Mouse model study shows QR-442 delays onset of multiple sclerosis and lowers severity
Myelodysplastic Syndrome - Encouraging data on Vidaza presented at American Society of Hematology meeting
Myelofibrosis - Revlimid trial shows 59% of evaluable patients with myelofibrosis responded to treatment
Nasal Polyps - Nasonex shown effective and safe for treatment of nasal polyps
Natural Products - Kempferol glycosides may mediate effects of Sedum dendroideum leaf juice
Neuroblastomas - ZD1839 inhibited neuroblastoma cell proliferation
Neurogenesis - Chronic HU210 treatment produces anxiolytic- and antidepressant-like effects
Neuroscience - Calpain sensitive regions identified in cytoplasmic domains of Gly transporters
Neuroscience - Ginkgolide B beta subunit increases sensitivity of inhibitory Gly receptors
Neuroscience - Reports advance knowledge in neuroscience research
Neuroscience - Stem cell therapy developer makes progress towards therapy for Parkinson disease
Non-Hodgkin Lymphoma - PDX shows promising activity in patients with resistant T-cell lymphomas
Non-Hodgkin Lymphoma - Phase II study shows Ontak benefits relapsed/refractory T-cell non-Hodgkin lymphoma patients
Non-Hodgkin Lymphoma - Positive data reported from phase II clinical trial of FavId following Rituxan
Non-Small Cell Lung Cancer - Pharma company receives regulatory clearance in the U.K. for phase III Combretastatin A4P trial
Non-Small Cell Lung Cancer - Phase II trial evaluating satraplatin plus Taxol in patients with advanced NSCLC begins
Nosocomial Infections - Continuous ceftazidime infusion superior to intermittent treatment in ventilated patients
Obesity Pathogenesis - Prepuberal induction of lithium-pilocarpine seizures can result in a lifetime of obesity
Obesity Therapy - Anti-obesity compound demonstrates statistically significant weight loss in phase IIb trial
Obesity Therapy - RGD-dependent disintegrin inhibited adipogenesis
Obesity Therapy - Updated cost utility model supports the use of orlistat to treat obesity
Obstetrics - Angiogenesis markers increase in pregnancy-induced hypertension
Oncology - Lymphangiogenesis promotes the dissemination of inflammatory breast cancer
Oncology - Research add new data to oncology body of knowledge
Ophthalmology - Chimeric protein targets ocular neovascularization
Ophthalmology - Studies describe new findings in ophthalmology research
Oral Epithelial Dysplasia - Pharma company receives license option for oral chemoprevention gel
Oral Mucositis - Encouraging preliminary top-line phase II results reported on velafermin
Ovarian Cancer - Intracellular topotecan may be mediated by gene products in ovarian cancer cells
Ovarian Cancer - KiSS1 suppresses metastasis in human ovarian cancer
Ovarian Cancer - Kinase inhibition sensitizes ovarian cancer cells
Pain Management - Collaboration to develop and commercialize VX-409, a new compound for the treatment of pain
Pain Management - Pharma company completes patient enrollment in phase IIa trial of oral pain medication
Pain Management - Positive results reported on abuse-resistant technology for narcotic analgesics
Pain Management - Research shows brain is an important part of pain control
Pain Management - TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli
Pancreatic Cancer - Extracellular matrix stimulates reactive oxygen species production in pancreatic cancer cells
Papillomatosis Therapy - Dysplasia reported with cidofovir for respiratory papillomatosis
Patents - Thymosin beta 4 wound healing technology receives patent in China
Patents - U.S. patent office awards patent for Biobarcode technology to nanotechnology company
Pediatric Epilepsy - High-dose adjunctive oxcarbazepine effective for partial seizure control
Peripheral Arterial Disease - Peripheral arterial disease guidelines recommend Plavix to reduce risk of heart attack
Personnel - Alzheimer disease therapy developer renews consulting agreement with Peter Davies
Personnel - Asthma drug developer appoints John Hodgman as chairman of board of directors
Personnel - Biopharma company appoints new members to the board of directors
Personnel - Biopharma company names Christian Frayssignes CEO of animal sciences
Personnel - Biopharma services organization appoints Todd A. Joron as corporate VP and general manager
Personnel - Biopharmaceutical company names Dr. Amir Pelleg chairman of the board; Dr. Manfred Mosk steps down
Personnel - Bruce A. Leicher joins company developing patient-specific immunotherapies as general counsel
Personnel - Cardiac drug maker expands management team
Personnel - Cleveland Clinic physician joins board of cardiovascular drug company
Personnel - DX-88 maker announces promotions of Thomas Beck, Clive Wood, and Ivana Magovcevic-Liebisch
Personnel - Dermatology drug maker adds two new trade relations senior executives
Personnel - Dr. Eve E. Slater appointed to drugmaker's board of directors
Personnel - Dr. George P. Shultz resigns from drugmakers's board of directors
Personnel - Dr. Joseph C. Maroon to serve as medical consultant to supplement retailer
Personnel - Dr. Joy L. Frestedt named vice president of clinical affairs for specialty pharma
Personnel - Drug discovery company appoints Kenneth Freeman as CFO
Personnel - Executive chairman of company developing multiple sclerosis therapy retires
Personnel - Inhaled drug developer expands executive management team
Personnel - John Ransom, PhD, named vice president of research, regenerative cell technology
Personnel - Lupus therapy developer's stockholders elect directors
Personnel - Medical therapies company establishes scientific advisory board
Personnel - Microalgae company names William R. Maris as CFO, VP finance and administration
Personnel - Nutritional supplements company appoints Dean DiMaria to VP of sales and marketing
Personnel - Oncology company appoints Kimberly A. Bergstrom as chief clinical officer
Personnel - Oncology company names Robert H. Armstrong VP, research & development, medical devices
Personnel - Oncology research company announces new member of scientific advisory board
Personnel - Pediatric pharmaceutical company appoints new VP, director
Personnel - Pharma company names Robert Colucci as vice president, clinical development
Personnel - Robert W. Karr named president at targeted immune therapy development firm
Personnel - Scott Myers named senior vice president, strategic marketing & commercialization
Personnel - Specialty pharma company elects J. Jay Lobell to board of directors
Personnel - Theodore van de Kamp joins advisory board of drug-delivery company
Pharmaceutical Research - Amantadine treatment not effective in small trial
Pharmaceutical Research - Dose de-escalation reflects biological response to SU5416
Pharmaceutical Research - Healthcare services firm executive publishes book about ROI in phase IIIB-IV research
Pharmaceutical Research - Market research firm study shows prelaunch research activities require greater financial support
Pharmaceutical Research - Market research study shows profitable pharma partnerships are mutually beneficial
Pharmacology - Human dopamine transporter is responsible for indirect effects on cocaine binding
Philanthropy - Foundation awards grants to improve community health in Washington and Oregon
Philanthropy - Gift allows cancer institute to establish proteomics research center
Product Licensing - Biopharma company and Novo Nordisk expand agreement to develop therapeutic protein
Product Licensing - Drug discovery company licenses BA058 for osteoporosis
Product Licensing - Gene Network Sciences licenses PathwayStudio Central software
Product Licensing - License to Johnson & Johnson's rapid exchange catheter delivery technology is acquired
Product Licensing - RP-606 for shingles treatment product rights revert to drug development company
Product Licensing - Vitamin D analog for prostate cancer licensed from Boston University Medical School
Prostate Cancer - Androgens may regulate proangiogenic growth factors
Prostate Cancer - Melastatine member is involved in channel activation in prostate cancer
Prostate Cancer - Perlecan knockdown diminishes prostate tumor vascularity and growth
Prostate Cancer - Phase I/II trial for CB7630 (abiraterone acetate) begins
Prostate Cancer - Quercetin inhibited prostate cancer cell proliferation
Prostate Cancer - Researchers describe findings in Prostate Cancer studies
Prostate Cancer - Rolling NDA submission begins for satraplatin in hormone refractory prostate cancer
Proteomics - Presenilin homologues function non-redundantly in proteolysis
Proteomics - Researchers' findings advance proteomics research
Proteomics - Transforming growth factor beta induction may treat pathological vascular disorders
Proteomics - Vascular endothelial growth factor receptors show interactions within endothelial cells
Public Health - AIDS therapy products included in World Health Organization prequalification list
Pulmonary Arterial Hypertension - Phase III trial of ambrisentan meets primary efficacy endpoint of improved exercise capacity
Pulmonary Hypertension - Pulmonary hypertension may be a common condition in paroxysmal nocturnal hemoglobinuria
Pulmonary Medicine - Findings describe new data in Pulmonary Medicine research
Rectal Cancer - Patient's preferences for adjuvant postoperative chemoradiation therapy in rectal cancer surveyed
Renal Cell Carcinoma - Dendritic cells generate tumor-reactive T cells
Renal Disease - Aminoguanidine stems pathological remodeling in peritoneal dialysis models
Renal Disease - Chromosomes 18 and X correlate with nephrotic-range proteinuria in animal models
Renal Disorders - Aldolase B autoantibodies detected in sera from patients with liver dysfunction
Respiratory Medicine - Evidence-based guidelines to be developed for treatment of idiopathic pulmonary fibrosis
Restless Legs Syndrome - Data suggest pramipexole relieves symptoms of restless legs syndrome
Restless Legs Syndrome - Study shows pramipexole delivers sustained efficacy in restless legs syndrome
Restructuring - Biopharma company announces new strategic plan to refocus on key programs
Restructuring - Pharma company announces new business model for Jenapharm GmbH & Co.KG subsidiary
Retinoblastoma - Long-term visual outcome following chemoreduction for retinoblastoma analyzed
Rheumatology - Biomechanical factors regulate angiogenesis in the bone and joint system
Rheumatology - Tissue kallikrein reduction changes angiogenesis patterns in systemic sclerosis
Rotavirus Gastroenteritis - Data from 70,000-infant phase III trials support the efficacy and safety of Rotateq vaccine
Schizophrenia - Combination clozapine-ziprasidone reduces the required daily dose of clozapine
Schizophrenia - Two studies show paliperidone extended release is effective in treating schizophrenia
Sinusitis - Option agreement signed with Mayo Foundation on treatment using intranasal antifungals
Smallpox - U.S. FDA accepts investigational new drug application for smallpox drug, grants fast-track status
Squamous Carcinoma - Immune response induced by liposomal transfection of squamous carcinoma cells
Statins - Article reviews ezetimibe/simvastatin (INEGY) treatment of hyperlipidemia
Statins - Ezetimibe/simvastatin is superior to atorvastatin in lipid-altering efficacy
Statins - Review suggests optimal goals for statin use in patients with CAD
Statins - Rosuvastatin improves LDL-C/HDL-C ratio more effectively than atorvastatin
Statins - Rosuvastatin is effective and less costly compared with other statins
Statins - Studies advance knowledge in statins research
Stem Cell Research - ALDHbr cells isolate human adult stem cells that can regenerate vascular function
Stem Cell Research - MRI detects brain tissues likely to undergo angiogenesis after cell therapy
Stem Cell Research - Research studies confirm promise of novel cord blood stem cell from biomedical company
Stem Cell Transplantation - Integrin and extracellular matrix interactions regulate hepatocyte engraftment
Stents - No correlation found between preinterventional plaque burden and neointimal hyperplasia
Stroke - Antiplatelet agent TRA-418 has neuroprotective activity in primate model
Stroke - Gene therapy enhances angiogenesis in brains with cerebral hypoperfusion
T Cells - Effector function mediated by gene-engineered T cells
T Cells - T cell depletion enhances dendritic cell cytotoxic T lymphocyte response
Testicular Germ Cell Tumors - Response of testicular germ cell tumors to chemotherapy analyzed
Thrombosis - New findings in thrombosis described
Transplant Medicine - Immunology transplantation tolerance study commences
Transplant Medicine - New data illuminates research in Transplant Medicine
Transplantation Medicine - GI complications, MMF dose adjustments are associated with negative transplant outcome
Tumor Therapy - DNA structural similarities revealed in several antitumor drugs
Tumor Therapy - Tumor eradication enhanced by interleukin electrotransfer
Type 2 Diabetes - Interleukin-18 neutralization lowers angiogenic activity in patients with background retinopathy
Type 2 Diabetes - Review discusses newly established concepts and therapies in type 2 diabetes
Vector Development - Liposomal characteristics influence therapeutic response in acute wounds
Venous Thromboembolism - Study shows 300,000 Americans die each year from complications of deep-vein thrombosis
Virology - Researchers detail new studies and findings in the area of virology
Virology - Virus-induced phosphorylation of PI3K/Akt and MAPK/ERK delays host cell apoptosis
West Nile Virus - First test to screen for West Nile Virus in donors of blood, organs, cells, and tissues approved
Wound Healing - Autologous bone marrow stem cells accelerate the repair of diabetic foot lesions
Wound Healing - DHEA accelerates cutaneous wound healing via estrogen receptors
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