Acetaminophen
Celecoxib treatment alters normal fracture healing in rats, acetaminophen treatment does not
Published in Drug Week, February 3rd, 2006
"This study compared the acute treatment effects of systemic analgesics with (celecoxib) and without anti-inflammatory activity (acetaminophen) on bone fracture healing," investigators in the United States report.
M. Bergenstock and colleagues, University Medicine & Dentistry New Jersey, performed a "[l]ongitudinal time study of fracture healing in rats. Closed, mid diaphyseal femur fractures were produced in female Sprague-Dawley rats.
"The rats were treated for 10 days after fracture with 60 or 300 mg/kg of acetaminophen, 3 or 6...
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Source: Drug Week (2006-02-03)
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