Published in Drug Week, February 24th, 2006
"The first purpose of this study was to simulate the impact of food intake on drug release and absorption in vivo using a novel in vitro system which mimics the gastrointestinal (GI) tract in man. The drug studied was acetaminophen in the form of immediate release (IR) tablets," investigators in France report.
S. Souliman and colleagues, Ingenierie et Developpement de l'Aliment et du Medicament, explained, "The second purpose was to establish a level A in vitro/in vivo correlation that could predict the bioavailability of a drug instead of using...
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