Hepatitis C Virus
HCV affects dendritic cell cytokine induction and T-cell stimulation
Published in Drug Week, March 10th, 2006
"The majority of HCV-infected individuals become chronically infected, which can result in liver cirrhosis and hepatocellular carcinoma. Patients with chronic HCV are unable to prime and maintain vigorous T-cell responses, which are required to rid the body of the viral infection."
"DCs are the professional antigen-presenting cells that probably play a dominant role in priming and maintaining vigorous T-cell...
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Source: Drug Week (2006-03-10)
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