Bladder Cancer
Bladder cancer inhibited by 1,1-bis(3'-indolyl)-1-(P-substitutedphenyl)methanes
Published in Drug Week, March 10th, 2006
According to recent research from the United States, "1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes containing p-trifluoromethyl (DIM-C-pPhCF(3)), p-t-butyl (DIM-C-pPhtBu), and phenyl (DIM-C-pPhC(6)H(5)) substituents have been identified as a new class of peroxisome proliferator-activated receptor gamma (PPAR gamma) agonists that exhibit antitumorigenic activity. The PPAR gamma-active C-DIMs have not previously been studied against bladder cancer."
"We investigated the effects of the PPAR gamma-active C-DIMs on bladder cancer cells in vitro and...
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Source: Drug Week (2006-03-10)
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