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Addiction Medicine



Team discovers possible "universal strategy" to combat addiction



March 24th, 2006

An international research team led by the University of Saskatchewan has discovered a signaling pathway in the brain involved in drug addiction, together with a method for blocking its action, that may point to a single treatment strategy for most addictions.

Their findings appear in the March issue of the journal Nature Medicine.

The team, led by Xia Zhang, associate professor in the U of S department of psychiatry, found that a naturally occurring enzyme known as PTEN acts on the part of the brain where many drugs of abuse exert their rewarding effects - the ventral tegmental area (VTA).

"Our results suggest a potential...


Source: Drug Week (2006-03-24)

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