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Adverse Drug Reaction



Oxaliplatin hypersensitivity reactions studied



March 24th, 2006

Hypersensitivity reactions to oxaliplatin were evaluated.

According to a study from the People's Republic of China, "A rising incidence of hypersensitivity reactions to oxaliplatin has been observed as a result of increasing clinical use. Epidemiological and clinical features of these reactions are reviewed."

"Records of patients treated with a modified FOLFOX regimen from March 1999 to March 2004 were reviewed. One hundred and eighty patients were identified. Twenty-seven patients (15%) have been labeled as allergic to oxaliplatin, the proportion being higher among those receiving oxaliplatin in palliative second-line or above settings (19.6%) than...


Source: Drug Week (2006-03-24)

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