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Allergy & Immunology
Pen ch 13 may contribute to asthma
March 24th, 2006
According to recent research from Taiwan, Pen ch 13 allergen induces secretion of mediators and degradation of occludin protein of human lung epithelial cells, and may therefore contribute to asthma. "Alkaline Ser proteases from six prevalent airborne Penicillium and Aspergillus species have been identified as a group of major allergens (group 13). After entering human airways, the allergens are in initial contacts with respiratory epithelial cells. "The purpose of this study is to investigate interactions between the Pen ch 13 allergen from P. chrysogenum and human lung epithelial cells," wrote H.Y. Tai and colleagues, Veterans General...
Source: Drug Week (2006-03-24)
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