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Alzheimer Disease
Anti-amyloid therapy may be an adjunct treatment for Alzheimer disease
March 24th, 2006
Anti-amyloid therapy may be an adjunct treatment for Alzheimer disease (AD). According to a study from the United States, "In AD there is increasing evidence that neurotoxicity is mediated by CNS inflammatory processes. These processes involve activation of microglia by amyloid-beta leading to release of pro-inflammatory cytokines including IL-1 beta, IL-6, and TNF-alpha among others." P.B. Rosenberg and colleagues from Johns Hopkins University wrote, "Neurotoxic processes mediated by these cytokines may include direct neuronal death by enhancement of apoptosis, decreased synaptic function as evidence by inhibition of long-term potentiation, and...
Source: Drug Week (2006-03-24)
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