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Atherosclerosis
Patients with high cholesterol levels benefit from simvastin treatment
March 24th, 2006
Patients with high cholesterol levels benefit from simvastin treatment. "Vascular endothelial growth factor plays a pivotal role in the progression of atherosclerotic lesions and causes instability of atherosclerotic plaques by inducing neoangiogenesis inside the current plaque. The pro-inflammatory cytokine interleukin (IL)-6 induces vascular endothelial growth factor in smooth muscle cells (SMC)," scientists in Austria report. "HMG-CoA reductase inhibitors (statins), display beside their lipid-lowering potency various pleiotropic effects. Such pleiotropic effects include improvement of endothelial dysfunction, increased nitric oxide...
Source: Drug Week (2006-03-24)
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