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Addiction Medicine
3,4-methylenedioxymethamphetamine acts most similarly to amphetamine
March 24th, 2006
3,4-methylenedioxymethamphetamine (MDMA) acts most similarly to amphetamine compared to other closely related compounds. According to a study from the United States, "In animals, two-choice drug discrimination studies have demonstrated that the behavioral effects of MDMA are mediated by dopaminergic and serotonergic systems. In order to delineate the relative role of these systems, three-choice paradigms have been used in animals, with findings indicating a more prominent role for serotonin." C.E. Johanson and colleagues from Wayne State University wrote, "Human studies assessing the subjective and physiological effects of MDMA have also indicated a...
Source: Drug Week (2006-03-24)
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