Head & Neck Cancer

Radiotherapy-induced mucositis in head and neck cancer patients treated by tetracaine gel

Published in Drug Week, March 31st, 2006

Radiotherapy (RT)-induced mucositis in head and neck cancer patients could be treated by tetracaine oral gel.

"We performed a phase II study to assess feasibility, pain relief, and toxicity of a tetracaine-based oral gel in the treatment of RT-induced mucositis. Fifty patients treated with RT for head-and-neck cancer with clinical evidence of acute oral mucositis of grade 2:2 were scheduled to receive the tetracaine gel. A questionnaire evaluating the effect of the gel was given to all subjects," scientists in Italy reported.

"In 38 patients (79.2%), a reduction in oral cavity pain was reported. Thirty-four patients (82.9%) reported no side effect....

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Source: Drug Week (2006-03-31)

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