Oral Squamous Cell Carcinoma
Oral squamous cell carcinoma apoptosis was induced by safingol
Published in Drug Week, March 31st, 2006
According to recent research from Japan, "PKC inhibitor safingol suppressed the growth of human oral SCC cells significantly at concentrations that inhibit PKC isoforms. Safingol inhibited the translocation of PKC following treatment with 12-o-tetradecanoylphorbol 13-acetate (TPA) in PKC alpha-EGFP-transfected cells, but not in PKC beta-EGFP-transfected cells, indicating selective inhibition for PKC alpha in oral SCC cells."
"Flow cytometric analysis and DNA analysis by agarose gel electrophoresis revealed an increase in the proportion...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Drug Week
Source: Drug Week (2006-03-31)
More Articles from Drug Week
- Azithromycin
Azithromycin is a potential therapy for Plasmodium vivax malaria in India - Drug Development
European regulatory authorities approve Glaxo SmithKline's Rotarix rotavirus vaccine - Influenza
Influenza symptoms receive reduced duration and severity from oseltamivir - Mental Health
Cipralex superiority supported by new data - Addiction Medicine
New findings in addiction medicine described - Addiction Medicine
Polymorphisms exist in the serotonin 1B receptor gene for heroin addiction - More from this issue of Drug Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
