Published in Drug Week, April 28th, 2006
Study 1: According to recent research from the Netherlands, the transmembrane domain of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) spike protein (S) functions during entry.
"The S of the SARS-CoV is responsible for receptor binding and membrane fusion. It contains a highly conserved transmembrane domain that consists of three parts: an N-terminal tryptophan-rich domain, a central domain, and a cysteine-rich C-terminal domain.
"The cytoplasmic tail of S has previously been shown to be required for assembly....
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Source: Drug Week (2006-04-28)
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