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Drug Week

Susan Hasty, Publisher

Table of Contents . . . May 12th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Drug Week | Other Publications

Acute Myocarditis - Olmesartan protects against coxsackievirus B3-associated acute myocarditis

Diabetes Therapy - Conformation-assisted PTP-1B inhibition may offer type 2 diabetes and obesity therapy

Diabetic Neuropathy - Dual-action peptides offer new strategy in diabetes-related neuropathy treatment

Drug Development -  Cryptococcus cell growth inhibited by recombinant single-chain anti-idiotypic antibodies

HIV/AIDS Therapy - Immunomodulators as an adjunct to antiretroviral drugs may enhance immune reconstitution

Acute Respiratory Distress Syndrome - Steroids do not prolong survival in intensive care patients with ARDS on life support

Adverse Drug Reaction - Acute liver failure could be caused by imatinib mesylate

Adverse Drug Reaction - Photodynamic therapy with verteporfin triggers back pain

Allergy & Immunology - Antigen-specific CD4+ T cell numbers can be expanded

Allergy & Immunology - Bifenthrin exposure can increase risk and frequency of inflammatory responses, diseases

Allergy & Immunology - IgG binding plant N-glycans were generated in rabbits but not in mice

Alveolar Cancer - Bronchoalveolar cell carcinoma is reduced by gene-modified dendritic cells

Angiology - Findings from the United States and Sweden advance knowledge in angiology research

Angiology - PPAR gamma agonists inhibit RAGE expression at sites of arterial injury

Angiology - Proper vascular development depends on calponin production

Angiology - Reports from the United States, Japan and Germany describe recent advances in angiology research

Angiology - Research from France, the South Korea and the United States in angiology provides new insights

Angiology - Researchers from Italy, the United States and Germany publish new studies and findings in the area of angiology

Angiology - Researchers from the United States, Scotland and People's Republic of China provide details of new studies and findings in the area of angiology

Anthrax - Researchers from the United States and South Korea describe findings in anthrax studies

Anthrax Vaccine Development - Anthrax protective antigen 2 beta(2)-2 beta(3) loop has dominant neutralizing epitope

Antibiotic Use - Less antibiotic use in food animals leads to less drug resistance in people, study shows

Antigens - Ezetimib influences the expression of raft-associated antigens in human monocytes

Antisense Technology - Antisense oligodeoxynucleotides can be delivered from cationically modified polymer films

Antisense Technology - Morpholino antisense oligonucleotides inhibit Oct4 expression

Antituberculosis Drug Adherence - Factors affecting patient adherence to DOTS in urban Kathmandu identified

Antivirals - Antiviral effect of liposome-mediated IL-28 and IL-29 demonstrated on WISH cells

Apoptosis - New findings from the United States in the area of apoptosis described

Apoptosis - Reports from India, Iran and Australia describe recent advances in apoptosis research

Apoptosis - Researchers' data from Germany, the United States and Scotland advance apoptosis research

Apoptosis - Researchers' work from Japan and the United Kingdom adds to apoptosis body of knowledge

Apoptosis - Role of osteoprotegerin in cancer reviewed

Arthritis - Researchers identify cause of heart problems with COX-2 inhibitors

Arthritis Therapy - Rofecoxib was compared with nabumetone for treatment of osteoarthritis

Arthritis Therapy - Tylophorine analog acts on arthritis by inhibiting innate immune response

Aspergillus Ustus Outbreaks -  Aspergillus ustus outbreak occurred among stem cell transplantation recipients

Asthma - Nebulized sodium cromoglycate a therapeutic option in severe asthma

Atherosclerosis - Recent findings from Japan, Italy and the United States illuminate research in atherosclerosis

Atherosclerosis - Researchers from Spain, Netherlands and Japan describe findings in atherosclerosis studies

Attention Deficit Hyperactivity Disorder - U.S. FDA approves methylphenidate patch to treat ADHD in children

Avian Influenza - Rothberg Institute promotes first computational international effort to fight avian flu

Awards - BIO presents James D. Watson Helix Awards to Genentech, Alnylam and Novo Nordisk

Awards - CytRx's Arimoclomol ranks in R&D Directions' "100 Great Investigational Drugs"

Awards - Neuromed named to Fierce 15 list of top emerging biotech companies in 2006

Awards - Pari Aerosol Research Institute receives medical design excellence award for eFlow Nebulizer

Awards - TargetRx CEO Mike Luby wins Philadelphia Business Journal's 40 Under 40 Award

Awards - U.S. Department of Commerce recognizes Mannatech for entry into international markets

Awards - William H. Foege, MD, MPH, receives 2006 Sabin Gold Medal for vaccine development

Biofilms - Biofilm formation may diminish antifungal efficacy during cryptococcal infection

Biomedical Engineering - Researchers' findings from Japan, Israel and the United States advance biomedical engineering research

Biomedical Engineering - Scientists develop new concept with potential to help predict how individuals may respond to drugs

Biotechnology - New Jersey making strong gains as a biotechnology leader, new study shows

Bladder Cancer - Bladder cancer management and outcomes reviewed

Bladder Cancer - Bladder cancer recurrence and progression predicted with risk tables

Bladder Cancer - Bladder cancers use VEGF receptor 2 as a vehicle for invasion

Bone Marrow Transplantation - Varicella zoster virus meningitis occurred following BMT despite valaciclovir prophylaxis

Botulinum Toxin Vaccine - DOR BioPharma announces advances in mucosal vaccines for botulinum toxin

Brain Cancer - Gliosarcoma growth tumbles after selective CYP4A inhibitor is administered

Breast Cancer - Benefit of chemotherapy in breast cancer depends on estrogen-receptor status

Breast Cancer - Breast cancer angiogenesis and invasion decline when uPA-uPAR signals are incapacitated

Breast Cancer - Breast cancer correlates with the expression of the FRA16D cancer gene

Breast Cancer - Breast cancer evaluated for residual tumor extent by three-dimensional MRI

Breast Cancer - Breast cancer favorable prognosis linked to pathologic complete response

Breast Cancer - Breast cancer fine needle aspiration cytology specimens contain overexpressed genes

Breast Cancer - Breast cancer outcome improved after primary systemic chemotherapy

Breast Cancer - Breast cancer patient's need for irradiation after conservative surgery studied

Breast Cancer - Breast cancer patients experienced chemotherapy-related neuropsychological impairment

Breast Cancer - Breast cancer treated by copper-dithiocarbamate

Breast Cancer - Ductal carcinoma in situ of the breast recurrence linked to wide excision

Breast Cancer - Mammographic density may be influenced by estrogen and progesterone receptor polymorphisms

Breast Cancer - Neoprobe completes regulatory submission for Lymphoseek for breast and skin cancer biopsies

Breast Cancer - New data from Croatia and the United States lluminates research in breast cancer

Breast Cancer - New data show no increased risk of breast cancer with conjugated estrogens alone

Breast Cancer - New findings from the United States and Switzerland in the area of breast cancer described

Breast Cancer - Reports from Sweden and Ireland describe recent advances in breast cancer research

Breast Cancer - Reports from the United Kingdom and United States describe recent advances in breast cancer research

Breast Cancer - Researchers' data from the United Kingdom advance breast cancer research

Business & Finance - Array BioPharma achieves milestone for selection of third compound for anticancer program

Business & Finance - BioProgress retains Roth Capital Partners as U.S. financial adviser

Business & Finance - Boston Life Sciences complies with NASDAQ rule regarding recently filed 10-K

Business & Finance - Gentium reports 2005 financial results, provides financial and clinical update

Business & Finance - Hana Biosciences obtains Nasdaq National Market listing approval

Business & Finance - Hemispherx receives noncompliance notice from AMEX

Business & Finance - Med Gen Inc. announces Australia, New Zealand and Finland to get new shipments of Snorenz

Business & Finance - MGI Pharma updates Q1 2006 outlook, expects $78 million in total revenues

Business & Finance - Octapharma reports 22% increase in sales

Business & Finance - Speedel Pharmaceuticals Inc. publishes first annual report as public company

Business Update - Affitech renews phage display license from German Cancer Research Center

Business Update - Aureus Pharma licenses Aurscope GPCR to Serono

Business Update - Bedford Laboratories begins shipping Mitoxantrone

Business Update - BioGaia signs sales agreement in France

Business Update - Biolex Therapeutics expands Medarex collaboration

Business Update - Biovail launches Wellbutrin XL to Canadian physicians

Business Update - Case Western Reserve University spins out stem cell company

Business Update - Celera Genomics announces sale of therapeutic programs to Pharmacyclics

Business Update - Dalton Pharma Services announces completion of GMP oligonucleotide manufacturing suite

Business Update - Dr. Reddy's receives U.S. FDA approval for fexofenadine hydrochloride tablets

Business Update - Expanded access program for Rexin-GTM provides genetic medicine to cancer patients

Business Update - Galenea Corp. to focus on development of CNS drugs

Business Update - Genelabs announces receipt of notice from Nasdaq, drug development restructuring

Business Update - IntraPrise Solutions releases upgrade of EMR system for data capture, processing

Business Update - Serono's controlling Bertarelli family terminates discussions on sale of the company

Business Update - Singapore budgets US$8 billion over next 5 years to expand research, development efforts

Business Update - Talecris Biotherapeutics to install StayinFront's suite of business applications

Business Update - VIASYS forms Theranox Inc. to explore gaseous nitric oxide use in treating chronic wounds

Cancer Gene Therapy - Adenovirus-mediated gene therapy in osteosarcoma cell lines can be sensitized

Cancer Gene Therapy - Breast cancer cell invasiveness is affected by matrix metalloproteinase

Cancer Gene Therapy - Breast cancer gene therapy effectiveness is increased by adenoviral vectors

Cancer Gene Therapy - Chemokine-expressing adenoviral vector suppresses tumors

Cancer Gene Therapy - Delivery of monocyte chemoattractant protein-1 gene enhances colon antitumor effects

Cancer Gene Therapy - Gene delivery to ovarian carcinoma nodes can be mediated

Cancer Gene Therapy - Gene therapy of human glioblastomas indicated by antiangiogenic activity of BAI1

Cancer Gene Therapy - Gene-based vaccination produces immune responses against PSMA

Cancer Gene Therapy - Growth arrest of head and neck cancer cells correlates with increased p16 and p53 expression

Cancer Gene Therapy - Interleukin gene therapy enhances ifosfamide activity against osteosarcoma lung metastases

Cancer Gene Therapy - Targeted cancer gene therapy for small-cell lung cancer utilizes a novel promoter

Cancer Gene Therapy - Transfection sensitizes tumor cells to etoposide-induced apoptosis

Cancer Research - EvoGenix in-licenses cancer antibody

Cancer Research - Reata announces RTA 402 entering clinical development as promising oral anticancer drug

Cancer Research - Researchers from the People's Republic of China, United States and Germany describe findings in cancer studies

Cancer Research - Studies from Spain and the United States add new findings to cancer body of knowledge

Cancer Research - Studies from the United States and Czech Republic advance knowledge in cancer research

Cancer Risk Factors - Combined estrogen and progestin therapy on cancer risk varies with cancer type

Cancer Risk Factors - Hyperinsulinemia garners colorectal epithelial proliferation

Cancer Therapy - Abegrin may offer three-pronged approach to cancer therapy

Cancer Therapy - Akt-activated cancer is suppressed by inhibited protein kinase activation

Cancer Therapy - CuraGen and TopoTarget present new preclinical data on PXD101 in treating cancer

Cancer Therapy - Impact of providing booklets about chemotherapy to newly diagnosed cancer patients studied

Cancer Therapy - Ovarian function preservation after Hyper-CVAD chemotherapy appears probable

Cancer Therapy - Peritoneal malignancies treated by cytoreductive surgery and intraperitoneal hyperthermic perfusion

Cancer Therapy - Peritoneal malignancy outcomes after peritonectomy and heated intraperitoneal chemotherapy studied

Cancer Therapy - Pulmonary toxicity linked to novel antineoplastic agents

Cancer Therapy - Thiazoloquinazolines found to be selective Aurora A and B kinase inhibitors

Cancer Therapy - U.S. FDA grants 510(k) clearance for implantable radiation sensor for treating cancer

Cancer Treatment - New findings from Germany, France and Israel in the area of cancer treatment detailed

Cancer Treatment - New findings from the United States and China in the area of cancer treatment described

Cancer Treatment - New findings in cancer treatment described from the United States

Cancer Treatment - New research from Germany, the United States and Switzerland in the area of cancer treatment detailed

Cancer Treatment - Recent studies from Belgium, Japan and the People's Republic of China add new data to cancer treatment research

Cancer Treatment - Recent studies from Taiwan, the United States and the United Kingdom add new data to cancer treatment research

Cancer Treatment - Research from Japan, Hungary and Netherlands in cancer treatment provides new insights

Cancer Treatment - Researchers from Italy, Germany and the the Netherlands report details of new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from Japan, the United States and Germany describe findings in cancer treatment studies

Cancer Treatment - Researchers from the United States detail new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers' work from Canada, Austria and Japan adds to cancer treatment body of knowledge

Cancer Vaccine - Cancer vaccine therapy is improved using genetically modified dendritic cells

Cancer Vaccine - Dendritic/tumor-fusion vaccine provides good clinical responses

Cancer Vaccine - Direct lentiviral vector administration induces antitumor immunity

Cardiac Transplantation - Patient blood test for gene expression can predict heart transplant rejection, study shows

Cardiology - Amiodarone is ineffective for the acute termination of sustained ventricular tachycardia

Cardiology - Bivalirudin is an effective anticoagulant for off-pump coronary artery bypass grafting

Cardiology - Findings from Germany and the United States in cardiology provide new insights

Cardiology - Findings from Israel, the United States and Australia describe new data in cardiology research

Cardiology - First onset atrial fibrillation is linked to elevated high-sensitivity C-reactive protein

Cardiology - Leukemia inhibitory factor regulation of cardiac stem cells may support neovascularization

Cardiology - New data from the United States and Israel lluminates research in cardiology

Cardiology - New findings from Germany, the United States and Canada in the area of cardiology described

Cardiology - New research from Canada and Italy in the area of cardiology detailed

Cardiology - Recent studies from Germany and the United States add new data to cardiology research

Cardiology - Research from the United States and People's Republic of China in cardiology provides new insights

Cardiology - Researchers from Belgium, Brazil and Turkey detail new studies and findings in the area of cardiology

Cardiology - Researchers from Japan and the United States provide details of new studies and findings in the area of cardiology

Cardiology - Researchers' data from the United States and Italy advance cardiology research

Cardiology - Researchers' data from the United States, Germany and Taiwan advance cardiology research

Cardiology - Researchers' work from Italy and the United States adds to cardiology body of knowledge

Cardiology - Simvastatin inhibits leptin-induced hypertrophy in cultured neonatal rat cardiomyocytes

Cardiology - Studies from Japan, Brazil and Sweden advance knowledge in cardiology research

Cardiovascular Disease - Acute coronary event risk is increased with high dietary methionine intake by middle-aged men

Cardiovascular Disease - Beta-blockers, ACE inhibitors, calcium-channel blockers are associated with reduced fracture risk

Cardiovascular Disease - Chronic ischemic mitral regurgitation is focus of review

Cardiovascular Disease - Obesity and cardiovascular disease continue to rise in developing countries

Cardiovascular Disease - Rimonabant may treat cardiometabolic risk factors in addition to obesity and diabetes

Cardiovascular Disease - Thiazolidinediones show potential for cardiovascular disease therapy

Cardiovascular Proteomics - Regulator of G protein signaling proteins may be cardiovascular therapeutic targets

Cardiovascular Research - Ifenprodil inhibits G protein-activated inwardly rectifying K+ channels

Cardiovascular Research - Platelet reactivity appears same or greater after aspirin therapy in women compared to men

Cardiovascular Research - Propionyl-L-carnitine prevents progression of cisplatin-induced cardiomyopathy in rat model

Cardiovascular Research - Review suggests an interaction between ibuprofen and aspirin

Cell Recruitment - CXCL16-mediated cell recruitment is dependent upon the MAPK pathway

Cervical Cancer - New findings in cervical cancer described from the United Kingdom, Japan and Germany

Cervical Dystonia - Study shows Myobloc demonstrates efficacy and safety in repeated dosing for up to 4 years

Chickenpox Vaccine - Routine varicella vaccination should be implemented in Saudi Arabia

Chondrosarcomas - Cranial base chondrosarcoma management described

Chronic Hepatitis - Chronic hepatitis C infection is associated with interleukin modulation

Chronic Myeloid Leukemia - Chronic myeloid leukemia response to imatinib predicted by quantitation of BCR-ABL transcript

Chronic Myeloid Leukemia - Leukemia patients receiving imatinib should be advised to practice adequate contraception

Clinical Trials - ACAT inhibition is not effective for limiting atherosclerosis and may promote atherogenesis

Clinical Trials - Chiron announces initiation of Phase 1 trial for CHIR-265 in melanoma

Clinical Trials - CombinatoRx reports preliminary data for drug candidate CRx-119 does not meet primary endpoint

Clinical Trials - Corautus announces termination of patient enrollment in GENASIS severe angina clinical trial

Clinical Trials - Cortex updates progress on clinical hold of AMPAKINE CX717

Clinical Trials - Dosing begun in phase 1 trial of anticancer treatment with Ecopia's ECO-4601

Clinical Trials - Dosing study initiated for GLP-1 agonist in metformin-treated patients with type 2 diabetes.

Clinical Trials - Emisphere completes enrollment for Phase II oral insulin clinical trial

Clinical Trials - Evaluation of risks and benefits of cancer clinical trials by review board members assessed

Clinical Trials - Generex Biotechnology announces results of Generex Oral-lyn trial for type 1 diabetes in youth

Clinical Trials - Herbals may be effective for low-back pain in the short-term

Clinical Trials - Immunization schedule in phase 1 trial of avian influenza vaccine completed by Sinovac

Clinical Trials - Labopharm reports positive results for phase 3 study of once-daily pain medication tramadol

Clinical Trials - Lilly reports preliminary coronary, breast cancer data from Raloxifene for heart trial

Clinical Trials - Quality of randomized controlled trials of brain tumor treatments assessed

Clinical Trials - Somaxon reports positive results in dosing trial of doxepin HC1 for adult chronic insomnia

Clinical Trials - Spectrum presents data from intravesical instillation trial of apaziquone in bladder cancer

Clinical Trials - Tigris initiates phase 2 trial of A-007 in patients with cervical intraepithelial neoplasia

Collaborations - 4SC, Institute of Molecular Virology sign pact to develop influenza therapies

Collaborations - Ablynx, Procter & Gamble extend Nanobody agreement

Collaborations - Adherex executes trial agreement for ADH-1 with the U.S. National Cancer Institute

Collaborations - Alnylam to collaborate with U.S. Army on RNAi therapeutics for biodefense threats

Collaborations - American Peptide signs manufacturing supply deal with Affymax

Collaborations - Avantrium announces strategic collaboration with BP

Collaborations - Burrill, Beijing Pharmaceutical form alliance for Pacific life sciences opportunities

Collaborations - Cell Signaling Technology announces continuation of collaboration with AstraZeneca

Collaborations - Chromos signs deal with AppTec for multiple sclerosis drug candidate

Collaborations - Correlagen Diagnostics and Protedyne Corporation partner to form Correlagen GeneXchange

Collaborations - Forest and Almirall announce a collaboration agreement on new therapy for COPD

Collaborations - GNI and Beijing Continent Pharmaceutical agree to form strategic alliance

Collaborations - InNexus Biotechnology and Affimed to collaborate on SuperAntibody technology

Collaborations - KineMed, Forbes Medi-Tech partner to discover noncardiovascular indications

Collaborations - Multiple Myeloma Research Consortium names MDS Pharma Services preferred CRO

Collaborations - Myriad and Abbott enter broad discovery collaboration to identify novel therapeutic targets

Collaborations - Oncotech and TherapySelect collaborate to offer cancer testing services in Germany

Collaborations - PsychoGenics and Sosei partner to identify new central nervous system therapies

Collaborations - SAFC Biosciences, Vivalis complete first stage of R&D collaboration on viral vaccines

Colon Cancer - Micronics receives phase I grant to develop early detection system for colon cancer

Colon Cancer - MoviPrep receives U.S. FDA approval letter

Colon Cancer - New data from Scotland, the United States and Netherlands lluminates research in colon cancer

Colon Cancer - Peritoneal colon cancer growth in rats is reduced by local antiangiogenesis therapy

Colon Cancer - Pretreated colorectal cancer patients show a response to cetuximab

Colon Cancer - Recent findings from Denmark, Greece and the United States illuminate research in colon cancer

Colorectal Cancer - Angiopoietin-2 expression in colorectal cancer is driven by hypoxia

Colorectal Cancer - Colorectal cancer outcomes were comparable between two chemotherapy regimens

Complementary & Alternative Medicine - Antihyperglycemic potentials of medicinal plants compared

Complementary & Alternative Medicine - Breast cancer patient quality of life improved with ginseng use

Contracts - Pacific Biometrics, Inc. awarded research contract as part of an innovative osteoporosis program

Cord Blood - Findings from the United States and Netherlands describe new data in cord blood research

DNA - Recent findings in DNA described by researchers from Japan, Belgium and Ireland

DNA Research - An shRNA barcode screen provides insight into cancer cell vulnerability

DNA Research - Endonuclease G participates in nucleosomal DNA fragmentation

DNA Vaccine - Canine IL-12 fused heterodimeric DNA enhances type 1 cytokine response

Dengue Fever - Recent studies from France, Brazil and the United States add new data to dengue fever research

Depression - Women need more comprehensive approach to managing depression

Depression Therapy - Suicidality is slightly increased in children taking antidepressant drugs

Dermatology - Ceragenix receives 510k clearance of EpiCeram for treatment of atopic dermatitis

Dermatology - Epidermolytic hyperkeratosis is caused by a human keratin 10 knockout

Diabetes - Data from Italy, Germany and the South Africa advance knowledge in diabetes research

Diabetes - Findings from Japan, the North Ireland and India in diabetes provide new insights

Diabetes - New data from Spain, Japan and the United States lluminates research in diabetes

Diabetes - New data from Switzerland and the United States lluminates research in diabetes

Diabetes - New findings in diabetes described from the United Kingdom, United States and Canada

Diabetes - New research from the United States in the area of diabetes detailed

Diabetes - Recent findings from the United States, Australia and Sweden illuminate research in diabetes

Diabetes - Reports from Japan, Hungary and Germany advance knowledge in diabetes research

Diabetes - Research from Canada, Spain and the United States add new data to diabetes body of knowledge

Diabetes - Research from the United Kingdom and United States in diabetes provides new insights

Diabetes - Research from the United States and Denmark add new data to diabetes body of knowledge

Diabetes - Research from the United States in diabetes provides new insights

Diabetes - Research from the United States, Canada and France add new data to diabetes body of knowledge

Diabetes - Research from the United States, Italy and Scotland in diabetes provides new insights

Diabetes - Researchers from Egypt, Cuba and the United States detail new studies and findings in the area of diabetes

Diabetes - Researchers from Japan, Belgium and Egypt publish new studies and findings in the area of diabetes

Diabetes - Researchers from Japan, Ireland and France detail new studies and findings in the area of diabetes

Diabetes - Researchers from the United Kingdom and United States describe findings in diabetes studies

Diabetes - Researchers from the United Kingdom, Japan and Finland report details of new studies and findings in the area of diabetes

Diabetes - Researchers from the United States, Sweden and France detail new studies and findings in the area of diabetes

Diabetes - Researchers' data from Japan and the United States advance diabetes research

Diabetes - Researchers' work from Canada, the United States and Sweden adds to diabetes body of knowledge

Diabetes & Depression - Fluoxetine therapy restored neuroplasticity-related hippocampal alterations of diabetic mice

Diabetes Complications - Diabetic endothelial progenitor cells deliver delayed reendothelialization due to thrombospondin-1

Diabetes Complications - Glucose and insulin administration may improve acute myocardial ischemia

Diabetes Pathogenesis - Insulin secretion controlled by mGlu5 metabotropic glutamate receptors

Diabetes Research - Researchers discover little difference between human insulin and faster-acting analogs

Diabetes Therapy - Addition of thiazolidinedione to sulfonylurea therapy lowers myocardial infarction risk

Diabetes Therapy - Bivalirudin and eptifibatide plus heparin reduced total thrombus formation and fibrin deposition

Diabetes Therapy - GLP-1, GIP and liraglutide may raise beta-cell replication and impact long-term diabetes therapy

Diabetes Therapy - Insulin therapy protects against most hypoglycemic counterregulatory defects in diabetic rat

Diabetes Therapy - Insulin treatment did not improve heart rhythm and physical activity in diabetic rat model

Diabetes Therapy - Rosiglitazone and atorvastatin improved lipid profiles and adiponectin levels in diabetes

Diabetes Therapy - Vanadyl sulfate reduces diabetes-related oxidative damage in stomach and spleen tissues

Diabetes Type 2 - Depomed data published on Glumetza, an FDA-approved treatment for type 2 diabetes

Diabetic Peripheral Neuropathy - Quigley to commence human testing of QR-333 topical diabetic peripheral neuropathy new drug

Diagnostics - Bladder cancer invasion genes are revealed in complementary deoxyribonucleic acid microarray

Diagnostics - Cancer patients bear circulating endothelial cells with select genetic markers

Diagnostics - New findings from India, Spain and Italy in the area of diagnostics described

Diagnostics - Researchers from Germany, the United Kingdom and the United States detail new studies and findings in the area of diagnostics

Diet & Nutrition - Acute hepatitis is inhibited by fermented brown rice and rice bran

Diet & Nutrition - In dyslipidemic subjects, combined dietary supplementation improves oxidative, inflammatory status

Diet & Nutrition - Mediterranean diet may influence coronary risk via gene-to-diet interaction on oxidized LDLs

Diet & Nutrition - New data from Australia, the United States and France lluminates research in diet & nutrition

Diet & Nutrition - Nutrition 21 receives commitment from a national retail chain for its Chromax product

Diet & Nutrition - Pediatric nutrition panel discusses difficulty of meeting older infants' nutritional needs

Disease Associations - Endometrial cancer patient developed Guillain-Barre syndrome after adjuvant chemoradiotherapy

Drug Delivery - Data from Wales, the United States and Japan advance knowledge in drug delivery research

Drug Delivery - Non-oral methylphenidate transdermal patch system for ADHD approved by U.S. FDA

Drug Delivery - Photochemical internalization augments EGF-saporin affinity toxin

Drug Delivery - Research from Japan, the South Korea and Singapore add new data to drug delivery body of knowledge

Drug Delivery - Sustained and targeted antiviral delivery to liver is achieved using emulsomes

Drug Development - Affymax begins clinical trial of Hematide to treat anemia in patients with aplasia

Drug Development - Aldagen IND for stem cell trial to treat critical limb ischemia is cleared by U.S. FDA

Drug Development - American Pharmaceutical Partners receives U.S. FDA approval for Mitoxantrone

Drug Development - Angiogenic function reacts to the synergy of laulimalide and docetaxel

Drug Development - Angiotech presents positive Adhibit data

Drug Development - Arixtra significantly reduced major bleeding compared to Lovenox

Drug Development - Astellas submits marketing application to EMEA for candin antifungal agent micafungin

Drug Development - Bayhill doses patients with multiple sclerosis in phase II trial, raises $15.8M

Drug Development - BioLineRx initiates phase I trials of BL-1020 for the treatment of schizophrenia

Drug Development - Boehringer Ingelheim's Sifrol/ Mirapexin treats restless legs syndrome

Drug Development - Cellegy's licensee for Tostrex in Europe has reported successful conclusion of E.U. MRP process

Drug Development - Degrasyn significantly reduces tumors in animal model of head, neck cancer

Drug Development - Different forms of the new agent vasohibin dominate angiogenesis

Drug Development - DiscoveRx expands PathHunter portfolio with release of homogeneous mitotic index assays

Drug Development - EUFLEXXA labeling extended to include room temperature storage

Drug Development - MGI Pharma submits NDA to U.S. FDA on oral glutamine for treating oral mucositis

Drug Development - Posaconazole was as effective as fluconazole in HIV/AIDS patients with oropharyngeal candidiasis

Drug Development - Pseudolarix acid B targets tubulin to fight angiogenesis

Drug Development - Safetek reports plans to develop muscarinic receptor antagonist for overactive bladder

Drug Development - Tumor cells and angiogenesis yield to a new transcriptional inhibitor

Drug Resistance -  Haemophilus influenzae cefotaxime resistance involves altered binding proteins

Drug Resistance - Galectin-3 makes prostate cancer resist cancer therapy by stabilizing mitochondria

Drug Resistance - Geographic differences in antimalarial efficacy in Uganda mediated by acquired immunity

Drug Resistance - Lamivudine resistance mutations studied in patients with chronic hepatitis B

Drug Resistance - Multidrug resistance in cancer targeted with newly developed drugs

Drug Resistance - T cell cytokine responses are dependent on multidrug resistance protein-1

Drug Resistance - Wyeth cites study on reduced antibiotic-resistant pneumococcal disease since Prevnar launch

Drug Toxicity - Mirtazapine does not have serotonergic effects in humans

Dyslipidemia - Statins may improve management of metabolic syndrome-induced coronary heart disease

Ebola Virus Vaccine - cAdVax-based bivalent Ebola vaccine induces immunity against Sudan and Zaire Ebola species

Ebola Virus Vaccine - Chimpanzee adenovirus vaccine protects against Zaire Ebola virus

Encephalitis - Findings from India, the United Kingdom and Japan describe new data in encephalitis research

End-Stage Renal Disease - Renin-angiotensin-aldosterone system blockade in diabetes can enhance renoprotection

Endocrinology - Calcitonin receptor-stimulating peptide-1 affects energy homeostasis

Endocrinology - New findings from Germany, Sweden and Italy in the area of endocrinology described

Endocrinology - New findings from Italy, Germany and Canada in the area of endocrinology detailed

Endocrinology - Thyroid hormone and its analog elicit angiogenesis at the cell surface

Endometrial Cancer - Endometrial cancer angiogenesis is assessed by vascular proliferation markers

Endometriosis - New data from the United States, Germany and Austria lluminates research in endometriosis

Enzymology - Fibroblast growth factor-2 initiates matrilysin expression in endothelial cells

Enzymology - Findings from Germany, the People's Republic of China and the United States advance knowledge in enzymology research

Erectile Dysfunction - BH4 is a potential therapy for erectile dysfunction

Esophageal Adenocarcinoma - Esophageal adenocarcinoma survival prognosticated by number of metastatic lymph nodes

Esophageal Cancer - Polo-like kinase and survivin are esophageal tumor-specific promoters

Fabry Disease - Amicus Therapeutics announces European regulatory status on Amigal for Fabry disease

Facilities - Antipodean Pharmaceuticals establishes San Francisco headquarters

Facilities - Asahi Glass to expand facility for recombinant protein for biopharmaceuticals

Facilities - CombiMatrix Molecular Diagnostics establishes facility in Toronto

Facilities - Companies leverage Singapore's research complex infrastructure to reduce costs and time-to-market

Finance - $6M grants support the advance of biomedical research

Finance - Acusphere prices common stock and warrant offering

Finance - Aethlon Medical submits Avian influenza treatment grant application

Finance - Affitech raises NOK 86 million in private placement

Finance - Allergan completes note offerings, redeems convertible notes due 2022

Finance - Amarin completes $4.2M financing

Finance - AspenBio Pharma closes $1,428,000 private placement

Finance - Baxter launches grant program to promote advancement in treatment of kidney disease

Finance - CombiMatrix and Texas A&M University receive grant, focus is DNA hybridization on microarrays

Finance - CryoFluor Therapeutics closes additional investment

Finance - DOR BioPharma announces private equity financing of $3.65 million

Finance - Fred Hutchinson Cancer Research Center receives boost from Susan G. Komen Foundation

Finance - Genentech announces 39% increase in 2006 first-quarter product sales over same period last year

Finance - Illumina expects to exceed financial guidance for the first quarter of 2006

Finance - Indiana-based Standard Management receives Nasdaq notice of low bid price for common stock

Finance - Isis Pharmaceuticals, Symphony GenIsis enter $75 million product development collaboration

Finance - Medarex prices initial public offering common stock at $11.75 per share

Finance - MicroIslet reports net loss of $8.5 million in 2005

Finance - Novagali Pharma completes EUR26 million financing to support phase III trials

Finance - Oscient Pharmaceuticals announces closing of $35.9 million private placement financing

Finance - Palatin Technologies, Inc. to raise $27 million in offering

Finance - Pharmos receives US$1.3 grant from Israel government

Finance - Prometheus Laboratories announces 2005 net revenues grew $140 million

Finance - QMed, Inc. reports $3,182,623 decrease in revenue for first quarter 2006

Finance - Stanford medical school receives first $1.2 million installment of state stem cell funding

Finance - StemCells, Inc. announces closing of common stock sale for gross proceeds of $35.8 million

Finance - Theranox raises $14 million to develop gaseous nitric oxide as chronic wound treatment

Finance - Vanda Pharmaceuticals announces IPO of 5,750,000 shares of common stock at $10 per share

Fitness & Wellness - Mechanism of glucose transporter 4 expression in muscle after exercise was determined

Fitness & Wellness - Nutraceutical products market growing in Southeast Asia

Gastric Cancer - New findings from Japan and Poland in the area of gastric cancer detailed

Gastroenterology - Findings from Greece, Japan and the United States in gastroenterology provide new insights

Gastroenterology - Recent findings in gastroenterology described by researchers from Sweden, the United States and the United Kingdom

Gastroenterology - Research from the United States, Germany and People's Republic of China in gastroenterology provides new insights

Gastroenterology - Researchers from the United States report recent findings in gastroenterology

Gastrointestinal Stromal Tumors - Gastrointestinal stromal tumors treated by surgery during imatinib mesylate therapy

Gene Delivery - Targeted gene delivery is facilitated by genospheres

Gene Research - Jefferson scientists uncover lethal gene mutation key to blocking cholesterol processing

Gene Research - St. Jude researchers develop new technique that could speed new medulloblastoma drugs

Gene Therapy - Calcitonin gene-related peptide receptor is activated by gene transfer

Gene Transfer - Gene transfer and enzyme replacement eliminates abnormal fibroblast sialylglycoproteins

Genetics - Recent findings from the United Kingdom, United States and South Korea illuminate research in genetics

Genetics - Reports from Austria, Italy and the United States add new data to genetics research

Genetics - Researchers from the United States detail new studies and findings in the area of genetics

Genetics - Studies from the United States and Japan add new findings to genetics body of knowledge

Genetics & Genomics - Gene profiling study identifies a unique G3139 molecular signature

Genetics & Genomics - No difference in genetic architecture for hemostatic factors was observed between males, females

Genetics & Genomics - Scientists discover a genetic switch that links animal growth and cancer

Germ Cell Cancer - Ovarian germ cell tumors in girls have excellent prognosis

Glioblastoma - Glioblastoma cell autophagy is regulated by elongation factor-2 kinase

Glioblastomas - Glioblastomas display little relation between cyclooxygenase-2 and VEGF

Gliomas - Glioma patient survival extended with Gliadel wafer as adjuvant chemotherapy

Gliomas - Gliomas are eradicated by von Hippel-Lindau tumor suppressor protein overexpression

Glottic Cancer - Glottic cancer treatment strategies evaluated

Gonorrhea - New findings from the United States and Australia in the area of gonorrhea described

Gynecology - Receptor cross-talk stimulates angiogenesis genes in endometrial tissues

HIV/AIDS - Data from France and the United States advance knowledge in HIV/AIDS research

HIV/AIDS - Findings from the United States advance knowledge in HIV/AIDS research

HIV/AIDS - New data from Netherlands, France and United States lluminates research in HIV/AIDS

HIV/AIDS - New findings from France, Spain and Brazil in the area of HIV/AIDS described

HIV/AIDS - New findings in HIV/AIDS described from the United Kingdom and Italy

HIV/AIDS - New research from Denmark, Russia and the United States in the area of HIV/AIDS detailed

HIV/AIDS - Recent studies from the United States and Netherlands add new data to HIV/AIDS research

HIV/AIDS - Reports from the United States and France advance knowledge in HIV/AIDS research

HIV/AIDS - Research from the United States in HIV/AIDS provides new insights

HIV/AIDS - Researchers from France and Italy provide details of new studies and findings in the area of HIV/AIDS

HIV/AIDS - Researchers from Switzerland, Australia and the United States provide details of new studies and findings in the area of HIV/AIDS

HIV/AIDS - Researchers from the People's Republic of China, United States and Sweden provide details of new studies and findings in the area of HIV/AIDS

HIV/AIDS - Researchers from the United States and Denmark publish new studies and findings in the area of HIV/AIDS

HIV/AIDS - Researchers from the United States and Japan publish new studies and findings in the area of HIV/AIDS

HIV/AIDS - Researchers from the United States and Spain provide details of new studies and findings in the area of HIV/AIDS

HIV/AIDS - Researchers' data from Belgium, the United States and the United Kingdom advance HIV/AIDS research

HIV/AIDS - Researchers' data from Spain and the United States advance HIV/AIDS research

HIV/AIDS - Researchers' work from the United States adds to HIV/AIDS body of knowledge

HIV/AIDS - Researchers' work from the United States and South Africa adds to HIV/AIDS body of knowledge

HIV/AIDS - Studies from the United Kingdom and United States describe new findings in HIV/AIDS research

HIV/AIDS - Studies from the United States, Italy and Sweden advance knowledge in HIV/AIDS research

HIV/AIDS Behavioral Medicine - HAART nonadherence factors determined for patients with HIV/AIDS

HIV/AIDS Dementia - Neuroactive antiretrovirals not related to neuropsychologic performance in stable HAART

HIV/AIDS Drug Development - Bi-functional betulinic acid derivatives have anti-HIV activity

HIV/AIDS Epidemiology - HIV-1 incidence low among married serodiscordant couples in Pune

HIV/AIDS Genetics & Genomics - Rate of drug resistance development may be similar for different HIV-1 subtypes

HIV/AIDS HAART - Clinical markers and tolerability similar among PI- or NRTI-based regimens in early infection

HIV/AIDS HAART - Nelfinavir-containing HAART strongly associated with virologic failure in young children

HIV/AIDS HAART - NNRTI and boosted PI regimens provide highest virologic success rates in HAART-naive patients

HIV/AIDS HAART - Partial treatment interruption of PI-based HAART is an option for children failing HAART

HIV/AIDS HAART - Zidovudine triphosphate not transformed to stavudine triphosphate in HIV/AIDS

HIV/AIDS Healthcare Costs - Healthcare costs increased in advanced AIDS while physician reimbursements are inadequate

HIV/AIDS Intervention - Predictors of intervention adherence among young people living with HIV determined

HIV/AIDS Mortality - HIV-1-related mortality increased in developing countries during first year of HAART

HIV/AIDS Pathogenesis - Brain-derived HIV envelope glycoproteins have a lower CD4 dependence

HIV/AIDS Pathogenesis - Coreceptor-targeted HIV entry inhibitors bridge gap towards infection cure

HIV/AIDS Pathogenesis - Exosomes and HIV Gag bud from endosome-like domains of T cell plasma membrane

HIV/AIDS Pathogenesis - HIV-2 Vpx nuclear localization signal residues required for efficient nondividing cell infection

HIV/AIDS Pathogenesis - IL-15 enhances chemokine secretion by NK cells from HIV viremic and aviremic patients

HIV/AIDS Pathogenesis - Morphine dependence contributes to SIV/SHIV pathogenesis

HIV/AIDS Prevention - Sexual risk reduction interventions do not increase overall sexual activity frequency

HIV/AIDS Screening - Routine HIV testing integrated into public health STD clinic

HIV/AIDS Survival - Neutropenia is not associated with decreased survival in HIV-infected women

HIV/AIDS Transmission - Heterosexual transmission likely route of HIV transmission in sub-Saharan Africa

HIV/AIDS Transmission - High perceived severity of HIV infection induces safe sexual behavior among gay men

HIV/AIDS Transmission - HIV transmission risk factors among bar and hotel workers in northern Tanzania determined

HIV/AIDS Vaccine - Robust HIV-specific immune responses were induced by DNA vaccine plus vaccinia virus boost

HIV/AIDS Virologic Response - HIV virologic response is a function of various factors

HIV/AIDS Wasting Syndrome - HIV gp120 interacts with chemokine system to generate HIV-wasting syndrome

HIV/AIDS-Associated Infection - Microsporidiosis common among HIV-infected persons in northwestern Venezuela

HIV/AIDS-Associated Kaposi Sarcoma - Noncutaneous and cutaneous AIDS-associated KS survival and immune response similar

HIV/AIDS-Related Bone Density - HIV-infected middle-aged women have reduced bone mineral density compared to uninfected women

HIV/AIDS-Related Cytomegalovirus Retinitis - Immune recovery associated with IOC increase in CMV-infected and noninfected eyes

HIV/Syphilis Coinfection - HIV infection associated with syphilis but does not affect treatment success

Head & Neck Cancer - Cutaneous squamous cell carcinoma managed by new staging system

Head & Neck Cancer - EGFR appears to regulate SP, may clarify EGFR's role in tumorigenesis in cancers of head and neck

Head & Neck Cancer - Head and neck cancer is controlled by therapy combining tetrathiomolybdate and radiation

Head & Neck Cancer - Head and neck cancers are propelled by proangiogenic autocrine loops

Head & Neck Cancer - New findings from Japan, Italy and Greece in the area of head & neck cancer described

Head & Neck Cancer - Researchers' data from Canada, the United States and Italy advance head & neck cancer research

Head & Neck Cancer - Squamous cell head and neck cancer treated by multiagent concurrent chemoradiotherapy

Head & Neck Cancer - Studies from Italy, the United States and the People's Republic of China describe new findings in head & neck cancer research

Headache & Migraine - Topiramate is effective for migraine prevention

Health Services - Regression-discontinuity analysis provides robust estimates of intervention effects

Healthcare Coverage - Aetna offers a co-pay-free period in New Jersey to promote appropriate generic use

Healthcare Coverage - Centers for Medicare and Medicaid Services (CMS) advises Niaspan is now Part D-eligible

Healthcare Coverage - Number of consumer-directed health plan clients surged in 2006; projected to double by 2007

Heart Attack - Recent studies from Netherlands, Israel and China add new data to heart attack research

Heart Attack - Researchers from Germany, the United States and Australia publish new studies and findings in the area of heart attack

Heart Attack - Researchers from New Zealand, United States and Japan provide details of new studies and findings in the area of heart attack

Heart Disease - Findings from the United Kingdom, France and Canada describe new data in heart disease research

Hemangiomas - Hemangioma treatment strategies and outcomes compared

Hematology - B beta-fibrinogen -455A allele may be related to erythrocyte aggregation in men only

Hematology - BioRx introduces program for hemophilia patients with inhibitors

Hematology - Cyclooxygenase-1 synthesis counteracts suppression of platelet thromboxane biosynthesis by aspirin

Hematology - Immediately after heart valve replacement, patients are more sensitive to warfarin

Hematology - Researchers from Austria and Italy provide details of new studies and findings in the area of hematology

Hepatitis B - Metabasis Therapeutics responds to plan by Valeant to out-license pradefovir

Hepatitis B Therapy - Hepatitis B treatment with lamivudine evaluated

Hepatitis B Vaccine - Chemoprevention in gastrointestinal cancers is focus of review

Hepatitis B Virus - Findings from Spain, Taiwan and Italy describe new data in hepatitis B virus research

Hepatitis B Virus - Hepatitis B core promoter mutations may not reduce promoter activity

Hepatitis B Virus - Hepatitis B surface antigen coexists with anti-HBs antibodies in chronic hepatitis-B virus carriers

Hepatitis B Virus - Hepatitis C virus lamivudine resistance responds to adefovir monotherapy

Hepatitis B Virus - High-dose hepatitis B virus vaccine is effective in chronic liver disease

Hepatitis B Virus - Research from Netherlands, Greece and Canada add new data to hepatitis B virus body of knowledge

Hepatitis B Virus - Researchers' data from Belgium, the United States and Turkey advance hepatitis B virus research

Hepatitis B Virus - Researchers' work from Taiwan, Japan and Belgium adds to hepatitis B virus body of knowledge

Hepatitis B Virus - Studies from Germany, Spain and France advance knowledge in hepatitis B virus research

Hepatitis C Therapy - Hepatitis C virus protease inhibitor resistance conferred by mutations

Hepatitis C Virus - HCV replicons enable simultaneous measurement of reporter activity and cell number

Hepatitis C Virus - Hepatitis C virus genotypes determined in real time

Hepatitis C Virus - Hepatitis C virus neutralizing human monoclonal antibodies evaluated

Hepatitis C Virus - Hepatitis C virus NS5B full form delays cell cycle progression

Hepatitis C Virus - Hepatitis C virus structural proteins expressed and processed in yeast

Hepatitis C Virus - Research from Taiwan, Germany and the United States add new data to hepatitis C virus body of knowledge

Hepatitis C Virus - Researchers from Austria and the United States report recent findings in hepatitis C virus

Hepatitis C Virus - Studies from the United States and Japan describe new findings in hepatitis C virus research

Hepatitis Therapy - Hepatitis severity is reduced by lamivudine in HBV carriers receiving chemotherapy

Hepatitis Therapy - Interferon therapy is influenced by mutations in the viral genome

Hepatocellular Carcinoma - New data from Italy and Japan lluminates research in hepatocellular carcinoma

Herpes Simplex Virus - HSV-TK-modified donor T cells limited after hematopoietic cell transplantation

Herpes Simplex Virus - Oncolytic recombinant herpes simplex virus treats orthotopic liver tumors

Herpes Simplex Virus - Synergistic herpes simplex virus cytotoxicity achieved using double suicide gene therapy

High Cholesterol - National Lipid Association statin study shows liver monitoring is unnecessary

Hodgkin Lymphoma - Classical Hodgkin lymphoma gene silencing involves epigenetic processes

Human Papillomavirus - Human papillomavirus vaccination utilizes recombinant adeno-associated virus

Hypertension - Data from France, the United States and Spain advance knowledge in hypertension research

Hypertension - Findings from Australia, Japan and the United States in hypertension provide new insights

Hypertension - Molecular mechanisms in hypertension-sodium link involve endogenous ouabain

Hypertension - Research from Canada, Netherlands and Taiwan add new data to hypertension body of knowledge

Hypertension - Research from France, Germany and Brazil in hypertension provides new insights

Imaging - Findings from Italy, the United States and Switzerland in imaging provide new insights

Imaging - Gold nanoparticles delineate angiogenesis in murine models

Imaging - Reports from Japan and the United States describe recent advances in imaging research

Imaging - Researchers from the United States and Belgium detail new studies and findings in the area of imaging

Immunization - Data show use of a combination vaccine increased on-time immunization rates in infants

Infectious Diseases - Avelox is as effective as Levofloxacin and Ceftriaxone combination to treat pneumonia

Influenza - New findings from the United States in the area of influenza described

Influenza Vaccine - DelSite Biotechnologies presents data on innovative influenza vaccine

Information Technology - Etrials contracts with pharmaceutical company to capture patient-reported trial outcomes

Information Technology - Image Solutions releases AnnoDoc 2.1

Information Technology - MemoText adds voice reminder calls to system to help patients remember medicines

Information Technology - Pharsight announces new DMX Web server release using Microsoft .NET framework

Information Technology - Simulations Plus releases software for pharmaceutical formulation research

Information Technology - Tecan to supply automated workstations for compound screening and profiling to Columbia University

Insomnia - MedPharm receives grant for insomnia nasal spray

Ischemia - Recent findings from France, the People's Republic of China and Japan illuminate research in ischemia

Ischemia - Recent findings in ischemia described by researchers from Netherlands, India and Japan

Ischemia - Researchers from the United States and Slovakia describe findings in ischemia studies

Kaposi Sarcoma-Associated Herpesvirus - KSHV LANA induces B cell hyperplasia and lymphoma

Legal Issues - Merck to appeal punitive and compensatory verdicts in New Jersey Vioxx product liability case

Legal Issues - Michigan Attorney General announces $370,000 settlement with GlaxoSmithKline

Leishmania - Findings from Germany, the United Kingdom and France advance knowledge in leishmania research

Leukemia - Leukemia drug sensitivity linked to lower gamma-glutamyl cysteine synthetase gene expression

Leukemia - New research from the United States, Japan and Germany in the area of leukemia detailed

Leukemia - Recent findings from China, France and Germany illuminate research in leukemia

Leukemia - Reports from Japan and the United States advance knowledge in leukemia research

Leukemia - Researchers attempt to unlock the mystery of acute lymphoblastic leukemia

Leukemia - Researchers' work from Sweden, the United States and the South Korea adds to leukemia body of knowledge

Leukemia Vaccine - Peritransplantation vaccination with chaperone-rich cell lysate induces antileukemic immunity

Licensing Agreements - AlphaRx, Proprius Pharmaceuticals sign license deal for Indaflex

Licensing Agreements - BioTime signs license agreement for China and Taiwan

Lipid Research - Inflammatory enzyme measured after coronary event is cardiovascular risk marker, data show

Liver Cancer - Liver cancers thrive on fasting-re-feeding regimens in rodent models

Lung Cancer - Accuracy of lung cancer detection improved by evaluating minimum lesion size

Lung Cancer - Advanced non-small-cell lung cancer treated by weekly docetaxel therapy

Lung Cancer - COX-2 inhibitors suppress lung cancer cell growth

Lung Cancer - Elderly lung cancer patients treated by carboplatin and paclitaxel as first-line chemotherapy

Lung Cancer - Inhibition of histone deacetylation may provide valuable approach for lung cancer therapy

Lung Cancer - Lung cancer linked to lower levels of retinoic acid

Lung Cancer - Lung cancer patients with low tobacco smoke exposures exhibit specific EGFR mutations

Lung Cancer - Lung cancer prognosis not predicted by p53, bcl-2, and Ki-67

Lung Cancer - Lung cancer treated by concomitant radiochemotherapy based on platin compounds

Lung Cancer - Lung cancer treated by modified intrapleural cisplatin therapy

Lung Cancer - New data from France, Japan and the United States lluminates research in lung cancer

Lung Cancer - Researchers' data from Japan, the United States and the People's Republic of China advance lung cancer research

Lung Cancer - Researchers' work from France and the United States adds to lung cancer body of knowledge

Lung Cancer Therapy - Genentech moves on Avastin with chemotherapy for nonsquamous, non-small-cell lung cancer

Lymphoma - Epstein-Barr virus-associated large B-cell lymphomas found resistant to standard chemoradiotherapy

Lymphoma - Researchers from the Saudi Arabia and Germany provide details of new studies and findings in the area of lymphoma

Macular Degeneration - Subretinal macular hemorrhage is managed by tissue plasminogen activator

Malaria Therapy - Mefloquine induces dose-related neurological effects in rat model

Malaria Vaccine Development -  Plasmodium vivax rhoptry-associated protein 1 identified and characterized

Market Analysis - A changing prescription for biotechnology challenges current business models

Market Analysis - Bioscience industry fuels jobs and growth for states

Market Analysis - Continence nurses in the U.S. aid patients in management of urinary incontinence

Market Analysis - Cutting Edge report says strategic pricing is hedge against generic drug competition

Market Analysis - Increased uptake of costly maintenance therapies to drive 9% annual growth in COPD market

Market Analysis - Kidney transplants are projected to increase, although the organ gap may widen further

Market Analysis - Patient health outcomes information will become a paramount form of business intelligence

Market Analysis - Report examines gastric cancer-targeted therapies

Market Analysis - Report suggests more rigorous evidence will be required in clinical evaluations

Market Analysis - Report suggests most tools used for toxicology and human safety testing are decades old

Market Analysis - Research and Markets report indicates bariatric surgery is an increasingly attractive option

Marketing - Accentia, Exaeris sign copromotion agreement for MD Turbo

Marketing - Analgesic market expected to grow to $75 billion by 2010, $105 billion by 2015, report says

Marketing - Malaysia offers collaborative opportunities to U.S. biotech companies

Measles - Researchers' work from Mexico and the United States adds to measles body of knowledge

Medical Devices - Advanced Medical subsidiary gets approval for human nebulizer testing

Medical Devices - AerovectRx receives U.S. FDA 510(k) clearance for nebulizer drug delivery system

Medical Devices - Impulse Dynamics announces first Optimizer implant successfully performed

Medical Devices - Intragastric balloon is safe and effective for moderate weight loss therapy in obese

Medical Devices - Medtronic receives FDA approval for insulin pump with real-time continuous glucose monitoring

Medical Devices - Nasal spray pump that is breath actuated improves delivery to target sites

Medical Devices - U.S. FDA grants regulatory approval, market launch of world's thinnest ICD lead

Medicare - New online tool introduced to track Medicare business

Medicare - Survey shows four in five seniors satisfied with their Medicare drug program coverage

Melanoma - Melanoma and metastases detected in vivo by iodide benzamides

Melanoma - New data from the United Kingdom, Italy and Canada lluminates research in melanoma

Melanoma - New findings from Denmark, the the Netherlands and Belgium in the area of melanoma described

Melanoma - Recent findings from Germany and the United States illuminate research in melanoma

Melanoma Vaccine - Inducible mouse model of melanoma expressing tumor antigen has been developed

Meningitis - Research from Italy and the United States add new data to meningitis body of knowledge

Mental Health - Chronic exposure to stress hormone causes anxiety and depression in mice

Mental Health - Estrogen may be protective against schizophrenia by inhibitive effect on buspirone

Mergers & Acquisitions - Adventrx signs definitive merger agreement with SD Pharmaceuticals

Mergers & Acquisitions - Athenagen acquires Osprey Pharmaceutical Company

Mergers & Acquisitions - Boston Scientific receives European Commission's clearance for Guidant transaction

Mergers & Acquisitions - Cellegy reports sale of Cellegy Australia to Epsilon Pharmaceuticals

Mergers & Acquisitions - Danaher Corporation announces recommended cash tender offer for Sybron Dental Specialties, Inc.

Mergers & Acquisitions - Discovery Partners International and Infinity Pharmaceuticals announce merger agreement

Mergers & Acquisitions - dj Orthopedics completes acquisition of Aircast Incorporated

Mergers & Acquisitions - Fisher Scientific expands biopharma services offering through acquisition

Mergers & Acquisitions - Longs enters agreement to purchase Network Pharmaceuticals stores for $10 million, assets

Mergers & Acquisitions - Misonix acquires controlling interest in UK-HIFU Limited

Mergers & Acquisitions - MM2 Group to acquire Genotec Nutritionals

Mergers & Acquisitions - Pfizer to expand neuroscience research with acquisition of Rinat Neuroscience

Metastasis - Researchers' findings from the United States and Japan advance metastasis research

Multiple Myeloma - Multiple myeloma-derived circulating endothelial cells may foster tumor vessel growth

Multiple Myeloma - Revlimid marketing authorization application accepted by EMEA for review

Multiple Myeloma Vaccine - Dendritic cells from multiple myeloma patients have impaired functionality

Multiple Sclerosis - Reports from the United States, Germany and Netherlands describe recent advances in multiple sclerosis research

Mycoplasma Vaccine - Live attenuated Mycoplasma synoviae vaccine was compared with wild-type parent strain

Myelodysplastic Syndrome - Myelodysplastic syndrome treated by anti-apoptotic cytokine therapy

Myeloma - Four additional cancer centers join Multiple Myeloma Research Consortium

Myocardial Infarction - Myocardial infarct size is reduced by vardenafil via opening of mitochondrial KATP channels

Nasal Polyposis - Superoxide dismutase isoforms are found at higher expression levels in nasal polyps

Nasopharyngeal Carcinoma - p53 protein and PCNA LI not correlated to 5-year survival rate in nasopharyngeal carcinoma

Natural Products - Cerebral ischemia injury in rats may be protected against by isoliquiritigenin

Natural Products - Naringin does not alter caffeine pharmacokinetics, energy use, or cardiovascular hemodynamics

Natural Products - Parsley extract shows protective effects against hepatotoxicity caused by diabetes

Natural Products - Quercetin improves endothelium-dependent relaxation, reduces contractility of hypertensive aortae

Nephrology - Phosphodiesterase 5 inhibitor improves renal resistance to obesity-related ANP

Neurology - Data from Germany, the United States and Italy advance knowledge in neurology research

Neurology - Researchers from France, the United Kingdom and Italy report recent findings in neurology

Neuroscience - Hippocampal up-regulation plays a key role on spatial memory

Non-Hodgkin Lymphoma - Non-Hodgkin lymphoma outcome not improved by addition of G-CSF

Nucleoside Analogs - Novel nucleoside analog for chronic hepatitis B reported

Obesity - Data from Canada, Israel and the United States advance knowledge in obesity research

Obesity - Findings from Canada, Italy and the United States in obesity provide new insights

Obesity - Findings from the United Kingdom and United States advance knowledge in obesity research

Obesity - New findings from Spain, the People's Republic of China and the United States in the area of obesity detailed

Obesity - Researchers from Finland and the United States publish new studies and findings in the area of obesity

Obesity - Studies from the United Kingdom and United States describe new findings in obesity research

Obesity Epidemiology - Leptin regulation and secretion before birth may influence early adult obesity programming

Obesity Pathogenesis - GABAA receptor antagonists prevent defects in leptin, insulin and amylin actions in obese

Obesity Therapy - Botulinum A toxin injected into gastric wall was safe treatment option for class III obesity

Obesity Therapy - Conjugated linoleic acid supplementation for 1 year does not prevent weight or body fat regain

Obstetrics - Popular prostaglandin pill for inducing labor is found effective, but concerns remain

Obstetrics - Researchers from India, the United States and Japan describe findings in obstetrics studies

Oncology - Data from Japan, the United States and Belgium advance knowledge in oncology research

Oncology - Findings from Japan, the United States and the United Kingdom advance knowledge in oncology research

Oncology - New findings from Switzerland and the United States in the area of oncology detailed

Oncology - Reports from the United States, South Korea and Japan advance knowledge in oncology research

Oncology - Research from the United States add new data to oncology body of knowledge

Oncology - The angiogenic switch of human cancer is portrayed in new tumor models

Ophthalmology - Corneal neovascularization submits to intravenous dihematoporphyrin ether and photodynamic therapy

Ophthalmology - Polypoidal choroidal vasculopathy and age-related macular degeneration have angiogenic differences

Ophthalmology - Progress is made toward global elimination by 2020 of blinding trachoma

Ophthalmology - Researchers from the United States and Netherlands provide details of new studies and findings in the area of ophthalmology

Oral Contraceptives - Post-molar trophoblastic neoplasia not likely linked to use of oral contraceptives

Orbital Carcinoid Metastases - Orbital carcinoid metastases surgical management and survival analyzed

Osteoarthritis - Osteoarthritic cartilage gene expression analyzed in intact and damaged regions

Osteoporosis - Researchers from Italy, Norway and Scotland describe findings in osteoporosis studies

Ovarian Cancer - Ovarian cancer invasion suppressed by overexpressed HOX genes

Ovarian Cancer - Ovarian cancer managed by diagnostic open laparoscopy

Ovarian Cancer - Researchers' data from the United States and People's Republic of China advance ovarian cancer research

Ovarian Tumors - Ovarian surface epithelial tumors are unlikely to respond to imatinib mesylate

Over-the-Counter Medications - Many over-the-counter medications in U.S. are found to be ineffective

Pain Management - Gender differences in pain perception may be related to circulating gonadal hormone

Pancreatic Cancer - MedPanel launches Profiles in Pancreatic Cancer - United States & Europe

Pancreatic Cancer - Pancreatic cancer progression does not require lymphatic angiogenesis

Pancreatic Endocrine Carcinoma - Predictors of pancreatic carcinoma response to somatostatin analogues identified

Papillomavirus - Researchers from the People's Republic of China, United States and Czech Republic provide details of new studies and findings in the area of papillomavirus

Patents - Arrowhead granted patent covering a new approach to targeted therapeutics

Patents - Cell Therapeutics, Inc. granted U.S. patent for antitubulin agents with anti-cancer activity

Patents - DOV Pharmaceutical, Inc. announces notice of patent allowance for novel form of bicifadine

Patents - Image Therm Engineering sues InnovaSystems for patent infringement

Patents - IMPAX comments on Wyeth's lawsuit related to generic versions of Effexor XR for depression

Patents - Mannatech successfully enforces Ambrotose patent against Bion/Elphanta

Patents - Meridian Bioscience Helicobacter pylori patent validated by settlement agreement with Astra

Patents - Oncolytics Biotech issued Canadian patent for methods of preventing reovirus

Pediatric Cardiology - Clinical trial is needed to determine best management of supraventricular tachycardia in infants

Pediatric Cardiology - For children with heart disease, Pediatric Heart Network offers primer for multicenter studies

Pediatric Vaccines - $1.5 billion needed to ensure 12-month stockpile of pediatric vaccines

Peripheral Vascular Disease - Recent studies from the People's Republic of China, Netherlands and United States add new data to peripheral vascular disease research

Personnel - Acrux appoints director of project management

Personnel - Anadys Pharmaceuticals appoints Robert Schooley to board

Personnel - ArQule announces management and board changes

Personnel - AtriCure appoints Gene R. McGrevin to its board of directors

Personnel - BioE appoints VP of finance and accounting

Personnel - Biota appoints VP of business development

Personnel - CEO to step down at Clinical Cell Culture

Personnel - CoTherix appoints Abhay Joshi as EVP and chief technical officer

Personnel - Donald Hayden named chairman of Vitae Pharmaceuticals board of directors

Personnel - Dr. Henry Esber nominated to Pro-Pharmaceuticals board

Personnel - Dr. James Paskavitz joins Paraexel as medical director

Personnel - Elizabeth Leininger, PhD, named StemCells VP of regulatory affairs, quality assurance

Personnel - EXACT Sciences announces changes to management team

Personnel - G. Steven Burrill, CEO, Burrill & Company, joins Phytomedics Inc. board of directors

Personnel - Genentech announces vice president appointments in commercial operations and product development

Personnel - ImaRx names Richard L. Love and Philip C. Ranker to board; Richard E. Otto named chair

Personnel - Indevus names president Andrew J. Ferrara to board, announces retirement of Harry Gray

Personnel - Invitrogen names NIH stem cell scientist Mahendra Rao, MD, PhD, to lead new research area

Personnel - Javelin names David Bernstein general counsel and chief intellectual property counsel

Personnel - Medistem establishes medical advisory board to guide stem cell technology research and applications

Personnel - MedPharm appoints Geoffrey Vernon as chairman

Personnel - Momenta Pharmaceuticals appoints Paul D. Goldenheim, MD to board of directors

Personnel - Neuromed Pharmaceuticals appoints Dr. Stephen Arneric to executive team

Personnel - New River Pharmaceuticals names John Thottathil chief scientific officer

Personnel - NextPharma Technologies board appoints Richard Milbank as chief financial officer

Personnel - NextPharma Technologies executive VP Dr. Hermann Osterwald appointed to the board of APV

Personnel - Pharsight appoints Will Frederick as chief financial officer

Personnel - Radius appoints Louis O'Dea as senior vice president and chief medical officer

Personnel - Savient announces proposed board changes, nomination of three independent directors

Personnel - Singapore attracts three scientists to spur translational and clinical research efforts

Personnel - Walgreens announces promotions of Huonker, Zimmerman and Linder to VP positions

Pharmaceutical Research - Acrux granted first grant in Europe, triggering payment from Lilly

Pharmaceutical Research - alpha-Blocker doxazosin improved BP in patients with hypertension and impaired glucose metabolism

Pharmaceutical Research - Antiangiogenic vinflunine blunts endothelial cell mobility

Pharmaceutical Research - Best Practices publishes benchmarking report focused on mergers and acquisitions

Pharmaceutical Research - Best Practices releases study examining pharma product relaunch

Pharmaceutical Research - Clinicians play major role in discovery of off-label drug therapies

Pharmaceutical Research - During ischemia/reperfusion injury, rotigaptide reduces infarct size and prevents arrhythmias

Pharmaceutical Research - Ischemic heart disease may be target for malonyl coenzyme A decarboxylase inhibitors

Pharmaceutical Research - Managed care report analyzes pharma industry's managed markets strategy and structure

Pharmacology - Pharmacokinetics of unbound drug predicted neutropenia for docetaxel

Philanthropy - Robert Wood Johnson University Hospital announces $5 million gift from Bristol-Myers Squibb

Phlebovirus Vaccine - Acute phleboviral infections are protected against by liposome-DNA complexes

Photodynamic Therapy - A VEGF competitor photosensitizes human endothelial cells

Pneumococcal Vaccine - Prior pneumococcal vaccination reduces morbidity in adults with pneumonia

Product Licensing - IDBS BioBook deployed globally for electronic experiment and study management at Pfizer

Product Licensing - Phyton Biotech signs licensing agreement with DiAthegen to commercialize growth hormone receptor

Product Licensing - Sunesis enters limited research, license agreement with UCSF for drug discovery technology

Prostate Cancer - Degarelix, a novel GnRH blocker from Ferring, moves into Phase III

Prostate Cancer - EDAP TMS S.A. presents 10-year experience for treatment of localized prostate cancer

Prostate Cancer - Geron Corporation announces multiple presentations on telomerase, other findings

Prostate Cancer - Illumina to conduct large-scale genotyping for U.K.-based research groups

Prostate Cancer - New findings from the United States and Australia in the area of prostate cancer detailed

Prostate Cancer - Prostate cancer apoptosis associated with C16 ceramide accumulation

Prostate Cancer - Prostate cancer models offer a way to study androgen independence and angiogenesis

Prostate Cancer - Prostate cancer progression associated with methyl-CpG- binding protein MECP2

Prostate Cancer - Prostate cancer treated by docetaxel or mitoxantrone as first-line chemotherapy

Prostate Cancer - Prostate cancer tumorigenesis is bolstered by angiogenesis chemokines

Prostate Cancer - Prostatic bone metastases discussed

Prostate Cancer - PTMA could be a target for prostate cancer therapy and diagnostic purposes

Prostate Cancer - Researchers from Canada and the United States report recent findings in prostate cancer

Proteins - New findings from Sweden, the United States and Japan in the area of proteins described

Proteins - New research from Wales and the United States in the area of proteins detailed

Proteomics - Angiogenesis may be triggered by low density lipoprotein receptor-related protein-1

Proteomics - Factor XIII elicits proangiogenic effects in mice

Proteomics - Insights on atherosclerosis pathophysiology are offered by proteomic analysis of rat aorta

Proteomics - S-nitrosylated proteins identified after deoxycholate exposure of colon epithelial cells

Proteomics - T-cell receptor peptide vaccine candidate restores FOXP3+ levels, Immune Response reports

Psoriasis - Psoriasis foundation awards four $30,000 research grants

Quality Assurance - For admitted African-American patients, congestive heart failure management improvements are needed

RNA - Reports from Taiwan, the United States and Israel add new data to RNA research

Radiation Therapy - Scientists observe that hyperthermia is the most potent radiation sensitizer known

Rectal Cancer - Rectal cancer treated by preoperative chemoradiation using oral capecitabine

Rectal Cancer - Rectal cancer treatment advanced by replacing 5-FU with oral capecitabine

Renal Transplantation - Thymoglobulin produces long-lasting CD4 cell suppression in HIV-infected kidney recipients

Retrovirus - New findings in retrovirus described from France, the United States and Germany

Rotavirus - New research from Finland, Venezuela and the United States in the area of rotavirus detailed

Rotavirus Vaccine - Protection against rotavirus shedding does not require intestinal IgA

SARS - Research from Austria, Taiwan and the People's Republic of China in SARS provides new insights

Sickle Cell Anemia - Actelion recruits for studies of sickle cell disease, pulmonary hypertension

Simian Immunodeficiency Virus - Simian immunodeficiency virus is a potent activator of IL-2 gene expression

Sinusitis - U.S. FDA grants Accentia Biopharmaceuticals Fast Track status for SinuNase

Spinal Cord Injury - Hypertension drug may reverse death or injury of nerve cells from spinal cord injury

Squamous Cell Carcinoma - Squamous cell carcinoma kinase A protein expression is down-regulated

Statins - New findings in statins described from Taiwan and Spain

Statins - Reports from Canada and the United States describe recent advances in statins research

Statins - Researchers' work from the United States and Japan adds to statins body of knowledge

Statins - Statins may inhibit ABCA1-mediated lipid efflux only in select conditions

Stem Cell Research - Aspirin abates endothelial progenitor cell proliferation and vasculogenic capacity

Stem Cell Research - Immortalized endothelial progenitor cells offer a way to study new vessel growth

Stem Cell Research - Stem cell transplants improve recovery in animal models for stroke, cerebral palsy

Streptococcus - New findings from Brazil and the United States in the area of streptococcus described

Stroke - Large study shows vision loss reduced in stroke, brain trauma patients with VRT therapy

Stroke - Research from Spain, the United States and the People's Republic of China in stroke provides new insights

Stroke - Researchers from Denmark, Italy and the United States report recent findings in stroke

Stroke - Researchers from Finland, the People's Republic of China and Switzerland detail new studies and findings in the area of stroke

Surgery - Researchers from Italy, Israel and Germany publish new studies and findings in the area of surgery

Surgical Technology - For patients receiving 3 or more sirolimus-eluting stents with PCI, outcomes are poorer

Testicular Cancer - Advances in testicular germ-cell cancer management discussed

Thrombospondin - Thrombospondin structural homology repeat functions in connective tissue growth

Thyroid Cancer - Thyroid cancer cell p53 family member function is inhibited by HMGA1

Tissue Engineering - Injectable PPF-based microsphere/scaffold developed for bone tissue engineering

Tissue Engineering - Percutaneous vertebroplasty can be successfully CT-guided

Toxicology - Brief exposures to 4-HC or PM can induce permanent follicle loss in ovaries

Transplants - New research from Denmark and the United States in the area of transplants detailed

Transplants - Research from Germany, the United States and Denmark add new data to transplants body of knowledge

Transplants - Researchers from Spain, the United States and Canada provide details of new studies and findings in the area of transplants

Transplants - Researchers from the United States, Italy and People's Republic of China publish new studies and findings in the area of transplants

Tuberculosis - Recent findings from New Zealand and Turkey illuminate research in tuberculosis

Tuberculosis - Researchers' work from the United States adds to tuberculosis body of knowledge

Tuberculosis Control - TB cure rate and drug compliance increase when physicians are involved in control program

Tuberculosis Research - Nude rat tuberculosis model mimics tuberculosis in immunocompromised humans

Tuberculosis Therapy - Multidrug-resistant tuberculosis cure rates improved by adjuvant resectional surgery

Tuberculosis Vaccine -  Mycobacterium bovis BCG expressing SIV Gag protein induces immune responses

Type 1 Diabetes - Transplantation of islets into diabetic primates results in prolonged blood sugar improvement

Urinary Incontinence - Periurethral mass formations may be late complication after bulking agent injection

Urology - New findings from Japan, the United States and Denmark in the area of urology detailed

Uterine Prolapse - Manchester operation offers good option to preserve uterus in uterine prolapse patients

Vaccine Delivery - Surfactant sodium lauryl sulfate enhances skin vaccination

Vaccine Development - Immunomics allows discovery of new targets for vaccines

Vaccine Efficacy - Vaccine efficacy measures should take disease transmission into account

Vaccines - Reports from Netherlands and United States advance knowledge in vaccines research

Vaccines - Researchers from the United States and Ireland describe findings in vaccines studies

Vaccinia Virus Vaccine - Vaccinia virus mutated in envelope proteins A33R and B5R are immunogenic

Vascular Disease & Hearing Loss - Vascular involvement is suggested in pathogenesis of sudden hearing loss

Vectors - New findings in vectors described from Germany, the United States and the People's Republic of China

Virology - Interferon signaling is inhibited by rabies virus phosphoprotein P

Virology - Recent findings in virology described by researchers from the United States

West Nile Virus Vaccine - West Nile virus vaccination is currently not cost effective

Wound Care - Mitomycin C evaluated for its ability to prevent airway stenosis during wound healing

Wound Healing - Calpain is a conduit for controlling vascular endothelial growth factor-related cell activity

Zoonosis - University of Liverpool to establish interdisciplinary Zoonosis Research Centre

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