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Drug Week

Susan Hasty, Publisher

Table of Contents . . . June 30th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Drug Week | Other Publications

Bacterial Meningitis Vaccine - Genome-based vaccine discovery evaluated against meningococcal B strains

Developmental Stuttering - Indevus reports promising phase II data for pagoclone in stuttering

Drug Development - Imagenetix announces positive safety studies on anti-inflammatory compound, 1-TDC

Drug Development - Panacos details study results of maturation inhibitor candidate for HIV

Drug Development - Regeneron receives fast-track designation for the IL-1 Trap in CIAS1-associated periodic syndromes

AIDS-Associated Kaposi Sarcoma - AIDS-associated KS prognostic index predicts mortality at initial diagnosis

Acute Lymphoblastic Leukemia - Bioenvision receives European approval for Evoltra

Acute Radiation Sickness - ImmuneRegen and ORNL announce initial results from Radilex testing

Adverse Drug Reaction - Adverse drug reactions were evaluated in large population of Medicare patients

Adverse Drug Reaction - Bortezomib causes severe pulmonary complications in Japanese patients

Adverse Drug Reaction - Clinical features of gemcitabine-associated lung injury are described

Adverse Drug Reaction - Linezolid can increase risk of serotonin toxicity

Allergy & Immunology - Autoimmune cholestatic liver diseases linked with high avidity anticardiolipin antibodies

Allergy & Immunology - Inspire to begin phase II testing of intranasal epinastine for seasonal allergic rhinitis

Allergy & Immunology - Neogen adds simple strip test for total milk allergen

Allergy & Immunology - Summer brings new crop of allergies

Allergy & Immunology - T cell receptor codon modification enhances functional expression

Alzheimer Disease - Byrd Alzheimer's Institute researcher study reveals new vaccine reverses memory loss

Alzheimer Disease - Memory Pharmaceuticals delays initiation of phase IIa trial of MEM 3454 for Alzheimer disease

Amyloidosis - Hereditary systemic amyloidosis amyloidogenic transthyretin can be selectively suppressed

Anal Cancer - Anal cancer could be treated by endosonographic-guided brachytherapy

Anaphylactic Shock - Dextran 1 given before clinical dextrans reduces anaphylactic shock risk

Anesthesia - General anesthesia for pulmonary embolectomy is often followed by hemodynamic collapse

Anesthesia - Sevoflurane anesthesia can significantly impair bronchociliary clearance

Angiology - Angiogenic growth proceeds without marrow cell incorporation after VEGF stimulation

Angiology - Intracranial aneurysms may be treated with endovascular coil embolization

Antibodies - Computational design enhances the affinity of a therapeutic antibody

Antimicrobial Resistance - Bacteria tested for susceptibility against piperazinyl-cross-linked fluoroquinolone dimers

Antimicrobials - Quorum-sensing inhibitors make biofilms more susceptible to antimicrobial treatments

Antituberculosis Drug - Physiological variability does not affect bioequivalence of fixed-dose rifampicin combinations

Apoptosis - Apoptosis is suppressed by a binding peptide aptamer

Apoptosis - Erythropoietin is unlikely to disrupt effectiveness of cancer chemotherapeutic drugs

Appendiceal Neoplasms - Appendiceal neoplasm treatments should consider intraperitoneal hyperthermic chemotherapy

Artificial Liver Support - Cell-free artificial liver support trial guidelines minimize systematic errors

Artificial Liver Support - Extracorporeal liver support device is a therapeutic option in artificial liver support

Asthma - Asthma management in children can be improved with school intervention programs

Asthma - BioMarin, Alliant report U.S. Food and Drug Administration approval of Orapred ODT

Atherosclerosis - Atherosclerosis, inflammation, and potential therapeutic role of folic acid are reviewed

Atherosclerosis - High-risk asymptomatic carotid artery disease treatment may include carotid artery stenting

Attention Deficit Hyperactivity Disorder - Shire announces significant ADHD symptom control reported with shorter Daytrana wear time

Avian Influenza Vaccine - DNA vaccine protects against avian influenza H9N2 virus challenge

Benign Prostatic Hyperplasia - Treatment of benign prostatic hyperplasia in context of comorbidities is reviewed

Bioartificial Liver - Optimal bioartificial liver system still under development

Biomedical Engineering - Fibroblasts provide a platform for analyzing angiogenesis

Bioterrorism - Viragen reports continued U.S. Army studies of Multiferon

Bladder Cancer - Bladder cancer apoptosis could be induced by curcumin

Blood Vessel Regeneration - CD11(low) cells are a good source of cells for blood vessel regeneration

Bone Marrow Transplantation - Survival improved for children requiring intensive care after bone marrow transplant

Brain Cancer - Glioblastoma growth is stunted by higher levels of transforming growth factor

Breast Cancer - Better survival seen for early breast cancer patients switched from tamoxifen to aromasin

Breast Cancer - Breast cancer anticancer agents identified in novel chalcone and bis-chalcone derivatives

Breast Cancer - Breast cancer treatment by flat dose versus body surface area dose compared

Breast Cancer - Breast tumor magnetic resonance images convey angiogenic parameters and prognostic information

Breast Cancer - Breast tumor response to tamoxifen as measured by estrogen receptor levels was evaluated

Breast Cancer - Tamoxifen may suppress appetite in obese women on breast cancer prevention therapy

Breast Cancer Diagnostics - Neurologic function tests may predict peripheral neuropathy in breast cancer patients

Breast Cancer Therapy - Genentech pursues Avastin with chemotherapy in treating some breast cancers

Breast Cancer Therapy - Herceptin plus Arimidex extends PFS in advanced HER2-positive breast cancer patients

Breast Cancer Therapy - Reduction of breast tumors with preoperative anastrozole therapy appears promising

Breast Cancer Therapy - Study demonstrates Genomic Health's Oncotype DX helps predict breast cancer survival

Breast Reconstruction - First three patients treated in clinical safety and feasibility study for breast reconstruction

Bronchitis - Smokers with chronic bronchitis generate excess angiogenesis protein

Brucellosis Vaccine - DNA vaccine encoding Brucella abortus genes is protective in mice

Burkholderia Outbreaks - Flagellin P-based PCR detected Burkholderia mallei in equine glanders outbreak

Business & Finance - Bioject completes financing and signs agreement

Business & Finance - Cyanotech reports fourth quarter and fiscal 2006 financial results

Business & Finance - DNAPrint Genomics updates first quarter business activity

Business & Finance - Dr. Reddy's reports FY06 revenue of Rs. 24 billion, net income of Rs. 1.6 million

Business & Finance - Pharmexa provide clinical pipeline, corporate update

Business & Finance - Schering-Plough announces changes to manufacturing operations in U.S. and Puerto Rico

Business & Finance - VSM withdraws public equity offering to pursue more comprehensive financing

Business Update - Actavis launches three new generic products in Europe

Business Update - Advanced BioHealing purchases Dermagraft and TransCyte

Business Update - Agilent Technologies launches technology to separate proteins and peptides

Business Update - Applied Biosystems, MDS Sciex accelerate drug discovery with new application

Business Update - Arrhythmia Research Technology participates in U.S. National Institutes of Health investigation

Business Update - Ascentia Biomedical shifts to biomedical arbitrage, development to achieve profitability

Business Update - Astellas terminates agreement on anti-osteoporosis agent FK481

Business Update - ATCC launches web-based standards search tool

Business Update - BioMag engages Manuel Lopez-Portillo to coordinate clinical trials, sales in Mexico

Business Update - Bristol-Myers Squibb extends neuroscience alliance with Lexicon Genetics

Business Update - Bruker Daltonics announces two application notes demonstrating its mass spectrometry performance

Business Update - Celtic Pharmaceutical selects Richard Lewis Communications to strengthen PR and patient recruitment

Business Update - Clinical data on Pharmion's marketed and pipeline products presented at ASCO annual meeting

Business Update - Dendrite International grows U.S. adherence programs

Business Update - DiscoveRx Corporation unveils new strategic direction

Business Update - EffRx, Inc. signs exclusive patent license agreement with Merck & Co., Inc.

Business Update - Integrated Genomics completes large multi-strain sequencing project

Business Update - Kerberos completes first clinical cases with new Peripheral Rinspiration system

Business Update - Merck corrects description of a statistical method used in APPROVe study; study results unchanged

Business Update - Two Israeli institutions purchase Partek Genomics Suite

Business Update - Varian Medical Systems hosts Beijing event for radiation oncologists and government officials

Business Update - Waters delivers complete exact mass solution for analysis of small molecules

Cancer Gene Therapy - Colon cancer cell growth is stopped by cyclooxygenase-2 gene silencing

Cancer Gene Therapy - RNA interference in breast cancer cells enhances the effect of tamoxifen

Cancer Nausea - Advanced cancer patients managed for nausea and vomiting with etiology-based guidelines

Cancer Research - Results of TNX-355 combination study published in Antimicrobial Agents and Chemotherapy

Cancer Therapy - Angiogenesis and cancer bow to the therapeutic properties of Actibind

Cancer Therapy - Anti-tumor immune responses enhanced by lung cancer cell fusion

Cancer Therapy - Cancer drug extends cognitive function in patients with brain metastases

Cancer Therapy - Cancer patients benefitting from personalized therapies

Cancer Therapy - CuraGen initiates second Phase II clinical trial with Velafermin

Cancer Therapy - Follow-up study of imatinib shows excellent results as treatment for chronic myelogenous leukemia

Cancer Therapy - Genes may raise risk of heart disease after treatment for childhood cancer

Cancer Therapy - Imanitib attacks prostate cancer in mouse model by destroying its blood supply

Cancer Therapy - Johnson & Johnson provides update on regulatory filing plans for Trabectedin

Cancer Therapy - Lilly launches phase III trial of once-daily, targeted oral cancer agent

Cancer Therapy - Melanoma received higher dose of diaminocyclohexane platinum from AP5346 than oxaliplatin

Cancer Therapy - New data show Camptosar is key to treating first line metastatic colorectal cancer

Cancer Therapy - New targeted therapy shows promise in children with metastatic gastrointestinal stromal tumor

Cancer Therapy - Photodynamic therapy-generated vaccine for cancer therapy is examined

Cancer Therapy - Preliminary study indicates sunitinib shows promise for treatment of renal cell cancer

Cancer Therapy - Recent research demonstrates the effectiveness of Thal/Dex therapy in treating multiple myeloma

Cancer Therapy - Symporter-mediated iodide transport stimulated in breast cancer cells

Cancer Therapy - Three-drug regimen improves survival in advanced head and neck cancers

Cancer Therapy - Vion initiates phase II trial of single agent Cloretazine in elderly patients

Cancer Therapy - Vitamin D targets thrombosis in cancer patients

Cancer Vaccine - Adenoviral vector expressing p53 gene may benefit patients with advanced cancer

Cancer Vaccine - Caution is needed when using reverse immunology to identify HLA-A2 binding epitopes in Tie-2

Cancer Vaccine - Insulin-like growth factor binding protein-4 is antitumorigenic

Cancer Vaccine - Self-antigen has been optimized for epitope presentation in cancer immunity

Candidiasis Therapy - Mycograb plus amphotericin B produced improvements for patients with candidiasis

Candidiasis Vaccine - Als1p N-terminal Candida vaccine has broad activity against disseminated candidiasis

Carcinogenesis - Human herpesvirus 8 chemokine receptor initiates endothelial cell proliferation

Cardiac Regeneration - Integrative studies are needed to achieve full potential of cardiac regeneration

Cardiology - A ventricular assist device with full magnetic suspension of the rotor has been developed

Cardiology - AMI-associated mortality is not correlated with coronary revascularization

Cardiology - Axial flow blood pump design may provide better pumping efficiency

Cardiology - Cardiac transmembrane protein structure and arrangement determined

Cardiology - Endotoxemic inflammatory pathways are not influenced by dobutamine

Cardiology - Implantable cardiac arrhythmia devices and appropriate therapy are reviewed

Cardiology - Left ventricular assist device-associated implantable electronic unit is developed

Cardiology - LVAD axial flow prototype with optimization of the magnetic suspension is designed

Cardiology - LVAD support restores myocardial beta-adrenergic receptor signaling

Cardiology - Sedation prior to coronary interventions may reduce myocardial damage

Cardiomyocytes - Ca2+ handling in myocardial injured rats was improved by trimetazidine

Cardiovascular Disease - ACE2 is therapeutic target for cardiovascular diseases

Cardiovascular Disease - Lipid therapy for heart disease prevention needs closer management, better adherence

Cardiovascular Disease - Relaxin's therapeutic potential in cardiovascular and renal disease is focus of review

Cardiovascular Research - Clot-busting drug helps revive cardiac arrest patients

Cardiovascular Research - Hemorrhagic shock treatment + pentoxifylline improves cardiovascular performance

Cardiovascular Research - Hypertrophic, myotoxic effects of clenbuterol are dose-determined in rat model

Cardiovascular Research - L-NAME-induced chronotropic response may involve humoral mechanisms

Cardiovascular Risk Factors - Coronary risk may be better marked by apolipoproteins than standard lipid profile

Cell Biology - PECAM-1 modulates the interactions of cells associated with inflammation and angiogenesis

Cell Biology - Telomerase immortalizes bovine microvascular endothelial cells

Cell Physiology - Erlectin functions in N-glycan recognition

Cell Therapy - Local platelet-rich plasma administration may stimulate intervertebral disc repair

Cell Therapy - Postinfarct cytokine therapy regenerates cardiac tissue and improves LV function

Cervical Cancer - Advanced cervical cancer therapy by routine concurrent chemoradiation may not be warranted

Cervical Cancer - Cervical cancer progression is fostered by integrin interactions with insulin-like growth factor 1

Chemotherapy - During chemotherapy, alternative food intake methods need to be considered to prevent malnutrition

Childhood Cancer - Neuroblastoma in offspring linked to maternal use of recreational drugs

Chromatography - Waters Corp. launches a new AutoPurification System

Chronic Obstructive Pulmonary Disease - COPD patients improve exercise tolerance, inspiratory muscle strength with L-carnitine

Chronic Obstructive Pulmonary Disease - Respiratory muscle strength in COPD patients was unaffected by angiotensin II receptor blockade

Clinical Trials - Atherosclerosis patients benefit from superior antiplatelet efficacy with higher dose AZD6140

Clinical Trials - Clot permeability, fibrinolysis are enhanced by statins, fenofibrate, and quinapril

Clinical Trials - Coalition of Cancer Cooperative Groups features Lance Armstrong in Newsweek supplement

Clinical Trials - Nucryst Pharmaceuticals appoints Dr. David Poorvin to the board of directors

Clinical Trials - Safety for heart patients taking lovastatin and warfarin was unaffected by moderate alcohol use

Collaborations - Applied Imaging to collaborate on E.U.-funded cancer research study

Collaborations - BioE, University of Newcastle form stem cell research partnership

Collaborations - Cambridge Laboratories signs marketing agreement for Nitoman

Collaborations - CombinatoRx and Cystic Fibrosis Foundation Therapeutics enter into a collaboration

Collaborations - EvoGenix announces antibody collaboration with CSL

Collaborations - KaloBios collaborates to engineer human antibody therapeutic drugs

Collaborations - Labopharm expands relationship with Glaxo Group

Collaborations - Murex Pharmaceuticals announces joint development agreement with Gene Network Sciences

Collaborations - Spectral, Somagen ink Canadian distribution agreement for rapid West Nile virus test

Collaborations - VaxGen concludes early stage meningitis B vaccine collaboration with EndoBiologics

Collaborations - Vical, AnGes to collaborate on Allovectin-7 and begin phase III trial

Colon Cancer - Advanced colon cancer is pervasive in California

Colon Cancer - Colon cancer chemoprevention and therapy finds new hope in acyclic retinoid

Colon Cancer - Replacing 5-fluorouracil/leucovorin with capecitabine in colon cancer adjuvant therapy advised

Colorectal Cancer - CCR6 a potential target for specific therapeutic interventions for colorectal cancer

Colorectal Cancer - Colon cancer cells with folate deficiency experience genetic alterations

Colorectal Cancer - Colorectal cancer patients tolerated bimonthly 12-hour 5-fluorouracil/irinotecan regimens

Colorectal Cancer - NeoPharm's LE-SN38 enters phase II trial in patients with metastatic colorectal cancer

Colorectal Cancer - Stage IV colorectal cancer associated with poor prognosis

Contraception - Levonorgestrel-releasing intrauterine system has good safety profile on lipid metabolism

Contraception - Nonpathological ovarian cysts may be associated with subdermal contraceptive implants

Contraception - Pregnancy ambivalence may increase abortion rates due to poor birth control compliance

Critical Care Medicine - Postextubation stridor incidence reduced with methylprednisolone injection

Cystic Fibrosis - CFTR cell surface expression is negatively regulated by calreticulin

DNA Research - Aberrant ocular albinism gene splicing can be corrected

DNA Research - DNA methylation may control retrotransposons in Entamoeba

Dendritic Cell Vaccine - Lentiviral vector expression of tumor antigens in dendritic cells is immunotherapeutic strategy

Dental Research - Dental implant surgery bone collectors tested for different clinical situations

Dental Research - Dental implants with copolymer surface layers may have enhanced bone apposition

Dental Research - Porous chitosan/collagen provides scaffolding for periodontal tissue engineering

Dental Research - Use of concentrated hydrogen peroxide tooth-whitening products may have harmful effects

Depression - Factors affecting depression relapse during fluvoxamine therapy are examined

Dermatology - Keratinocyte transcriptome reveals links to cell differentiation and functions

Developmental Biology - Connective tissue growth factor stimulates fibroblast collagen deposition

Developmental Biology - Oct4 homologues aid in maintaining vertebrate developmental multipotency

Diabetes & Coronary Artery Disease - Pioglitazone improves endothelial dysfunction and insulin sensitivity in type 2 diabetes

Diabetes Complications - Diabetes impairs the ability of transplanted cells to stimulate angiogenesis in ischemic limbs

Diabetes Complications - Immunoglobulin A1 may exert partial periodontal tissue protection in diabetics

Diabetes Pathogenesis - Dexamethasone induced cell death in insulin-secreting cells is reversed by exendin-4

Diabetes Pathogenesis - Impaired fasting glucose and impaired glucose tolerance linked to reduced insulin secretion

Diabetes Prevention - Diabetes prevention may involve lifestyle changes or medication

Diabetes Research - Increased sensitivity to nerve signals keeps diabetes at bay

Diabetes Therapy - Antidiabetic actions of oligofructose require functional glucagon-like peptide 1 receptor

Diabetes Therapy - Dual glucagon antagonist and GLP-1 agonist receptors may be diabetes therapeutic agent

Diabetes Therapy - Islet cell transplantation significantly improves glycemic control in diabetes

Diabetes Therapy - Liver X receptor activation promotes lipid accumulation but does not alter insulin action

Diabetes Therapy - Microcirculatory pathology in diabetes patients is not corrected by pioglitazone

Diabetes Therapy - Muraglitazar improved glycemic control, triglycerides, and HDL cholesterol in type 2 diabetes

Diabetes Therapy - Potential diabetes gene therapy using Epstein-Barr Virus vector has been developed

Diabetes Therapy - PPAR alpha agonist fenofibrate improves diabetic nephropathy in db/db mice

Diabetes Therapy - Rosiglitazone might be effective in reducing metabolic syndrome prevalence

Diabetic Nephropathy - Kidney pathology is restricted in diabetes models treated with an isocoumarin

Diabetic Nephropathy - Tissues from patients with diabetic nephropathy suggest angiogenic impairment

Diabetic Neuropathy - Diabetic neuropathy in rat models improves after basic fibroblast growth factor therapy

Diabetic Retinopathy - Diabetic retinopathy is limited by treatment with lipoic acid

Diabetic Retinopathy - Patients with diabetic retinopathy display elevated matrix metalloproteinase levels

Diagnostics - Coronary microcirculation assessed by an index is independent of hemodynamic perturbations

Diagnostics - Polymedco offers lipid, lipoprotein assays for research

Diagnostics - VAP cholesterol test uncovers polycystic ovarian syndrome

Diet & Nutrition - Delphinidin blocks the phosphorylation of vascular endothelial growth factor receptor-2

Diet & Nutrition - Next Pharmaceuticals announces new delivery form for Relora, microencapsulated concentrate

Disease Associations - C-reactive protein modulates nitric oxide and superoxide in rat mesangial cells

Disease Associations - Homocysteine reduction in end-stage renal disease with vitamin B12 holds promise

Drug Abuse - Opioid addiction presents a major public health threat in Atlanta, Georgia

Drug Abuse - Opioids should be prescribed dynamically, according to aggressiveness of the cancer

Drug Delivery - DNA-releasing microspheres aid DNA vaccine development

Drug Delivery - MDI-delivered BDP microparticles stabilized with PVA and PVP coatings

Drug Development - Astellas Pharma submits application for FK506 in Japan

Drug Development - Carbinolamines 8A developed as new class of lead structures for anticancer drug design

Drug Development - Carbonyl- and sulfur-containing analogs of suberoylanilide hydroxamic acid developed

Drug Development - Chimerix acquires compound library of antiviral agents from University of Michigan

Drug Development - Corautus Genetics announces filing of response to U.S. Food and Drug Administration clinical hold

Drug Development - Data from Sangamo BioSciences' Diabetic Neuropathy Program published in Diabetes

Drug Development - Lupin announces final U.S. Food and Drug Administration approval of Cefdinir Capsules

Drug Development - Neurochem developing tramiprosate to treat Alzheimer disease

Drug Development - Targeted Genetics presents encouraging interim data from trial of tgAAC94

Drug Development - The U.S. Food and Drug Administration's reputation with the general public is under attack

Drug Development - VioQuest Pharmaceuticals initiates phase I/II trial of VQD-002 for solid tumors

Drug Resistance - 3 Point Blue commercializes child resistant solution to blister packed drugs

Drug Resistance - Bacterial pathogen susceptibility to carbapenems and other broad-spectrum agents monitored

Drug Resistance - Chromosome microdissection identified genomic amplifications associated with drug resistance

Drug Safety - Allometric methods to predict drug clearance in children are compared

Drug Safety - Elevation of myocardial infarction risk is a class effect of COX-2 inhibitors

Drug Safety - Tolerability and safety of fluvoxamine and other antidepressants are considered in review

Dysphagia - Chronic dysphagia management requires a team approach

E. Coli Vaccine - Levamisole synergizes E. coli vaccine to stimulate Peyer's patch T cells

Embryogenesis - Gonadotropins affect Oct-4 gene expression during mouse oocyte growth

Embryonic Stem Cell Research - Human embryonic stem cells propagated on immortalized drug-resistant cell line

Endometrial Carcinoma - Endometrial carcinomas affected by anti-tumor herbal medicines

Epidemiology - Beta-lactam-resistant invasive Streptococcus pneumoniae is increasing in Brazil

Epstein-Barr Virus - Multiple domains of Epstein-Barr virus noncoding RNA recruit ribosomal protein L22

Erectile Dysfunction - Sildenafil improves self-esteem and confidence in men with erectile dysfunction

Facilities - Bio-Bridge Science completes construction of facility to produce vaccines

Facilities - Bristol-Myers Squibb to build new biologics facility in Massachusetts

Facilities - Invitrogen expands production capabilities of animal-origin free AGT media formulation

Facilities - TKL expands, relocates corporate headquarters

Fatty Liver Disease - Treatment options for nonalcoholic fatty liver disease are reviewed

Finance - Acura Pharmaceuticals secures bridge funding

Finance - AstraZeneca invests $100M in China research and development

Finance - Biovail commences offer to purchase $56.6M of its subordinated notes

Finance - Cangene awarded $362M supply contract by U.S. government for anti-botulism drug

Finance - Corautus Genetics receives NASDAQ deficiency notice related to minimum bid price

Finance - CV Therapeutics reports option grants under Nasdaq Marketplace Rule 4350

Finance - Dutton Associates announces investment opinion on Oragenics, initial rating at Speculative Buy

Finance - FoldRx Pharmaceuticals closes $43 million Series B financing

Finance - Gentium raises $22.1 million in private offering to support pipeline development

Finance - Helix BioMedix reports first-quarter net loss of $822,300

Finance - Isis Pharmaceuticals receives $75M equity financing commitment

Finance - King Pharmaceuticals extends cash tender offer

Finance - Lab Research files preliminary prospectus for its initial public offering

Finance - PainCare waives approximately $1.6 million in bonuses earned, but not paid

Finance - Profectus BioSciences announces additional $3 million private placement of equity securities

Finance - Proteolix closes $45 million financing to support expansion of clinical trials of PR-171

Finance - Raptor Pharmaceutical Inc. completes reverse merger of Highland Clan Creations

Finance - Targacept reports net quarterly loss of $5.2M

Finance - University Hospitals of Cleveland receives $250,000 grant for breast cancer research

Finance - Xechem's subsidiary receives N150M Naira loan from Nexim Bank

Food Allergies - Case studies suggest direct relationship between tacrolimus, development of food allergy

Gastric Adenocarcinoma - Gastric adenocarcinoma progression linked to Net1 and Myeov gene expression

Gastric Cancer - Gastric cancer treatment with S-1 combined with irinotecan deemed effective

Gastroenterology - Diagnosis and management of esophageal spasm is subject of review

Gastroenterology - Five-year study confirms Gleevec's long-term benefits

Gastroesophageal Reflux Disease - Suboptimal proton pump inhibitor dosing is prevalent in GERD patients

Genetics & Genomics - Ludwig Maximilian's researchers discover a mechanism that activates, regulates Bcl-3

Genetics & Genomics - Max Planck Institute of Biochemistry researchers, colleagues catalogue proteins

Genetics & Genomics - Steroid receptor coactivators' ablation affects hepatic metabolism

Geriatrics - Statins for cardiovascular prevention therapy in the elderly are reviewed

Glaucoma - Glaucoma treatment with Baerveldt 250-mm2 implant shows good intermediate-term success

Graft-versus-Host Disease - CCL27/CTACK-CCR10 interaction recruits CD4 cells to skin in graft-versus-host disease

Graft-versus-Host Disease - Response favorable for extracorporeal photopheresis in children with GVHD

HIV/AIDS Education - Microsoft and PBS create global web resource to enhance understanding of AIDS pandemic

HIV/AIDS HAART - Aboriginal IDUs have lower HAART uptake than non-Aboriginals over 24-months

HIV/AIDS Healthcare - Community-based HIV treatment service maintains efficacy after rapid scale-up

HIV/AIDS News Media - Australian community-based HIV media presents aura of ambivalence about HAART strategies

HIV/AIDS Polyneuropathy - HIV-1 gp120 causes neuronal apoptosis and axonal degeneration via 2 mechanisms

HIV/AIDS Risk Reporting - Audio computer-assisted self-interview improves HIV risk reporting among substance abusers

HIV/AIDS Therapy - HIV protease carrying indinavir drug-resistance mutations is characterized

HIV/AIDS Therapy - Randomized trial of DAART and IACM intervention shows no improvement of short-term outcomes

HIV/AIDS Vaccine - Intracellular trafficking and assembly pathway for HIV-1 Gag has been identified

HIV/AIDS Vaginal Microbicide - Vaginal microbicides are being developed to prevent HIV transmission

Head & Neck Cancer - Head and neck cancer patient quality of life not improved with mistletoe extracts

Head & Neck Cancer - Head and neck cancer patients treated with intensity-modulated radiation therapy

Healthcare Access - Government forcing another tough choice in picking long-term care plan

Healthcare Coverage - Merck to create new patient assistance program for vaccines

Heart Failure - Heart failure risk is important to reduce by management of RVA pacing

Heart Failure - Scios to begin international outcomes trial of Natrecor for decompensated heart failure in 2007

Heart Transplantation - Artificial heart malfunction may be detected with an automatic diagnosis system

Heart Transplantation - Blood pump leakage flow rate associated with surface roughness and gap clearance

Heart Transplantation - Centrifugal rotary blood pump can detect left ventricular function

Hematology - Bivalirudin anticoagulation is monitored by Thrombelastograph ecarin clotting time assay

Hematology - Cardiopulmonary bypass is associated with degradation of tissue factor pathway inhibitor

Hematology - Platelet angiostatin propels angiogenesis with the help of urokinase plasminogen activator

Hematology - Thrombogenesis is enhanced by fibronectin cross-linking to fibrin and assembly in platelet thrombi

Hematopoietic Tumors - Hematopoietic tumor treatment should involve developing therapies that target HAUSP

Hepatitis C Virus - Hepatitis C virus coinfection increases mortality in HIV-infected individuals

Hepatitis C Virus - Hepatitis C virus-associated diabetes may involve insulin resistance

Hepatitis Vaccine - Hepatitis B vaccination trait positive affect and antibody response clarified

Hepatitis Vaccine - PLGA microspheres evaluated in single-dose hepatitis B virus vaccine

Herpes Simplex Virus Type 2 Vaccine - Recombinant vesicular stomatitis virus vector immunogenic against HSV-2

Homozygous Familial Hypercholesterolemia - Isis Pharmaceuticals receives orphan drug status for ISIS 301012 for high cholesterol

Hormone Therapy - Developing novel hormone therapy delivery systems may enhance efficacy and compliance

Hypertension - Antihypertensive therapeutic potential of renin inhibition is focus of review

Hypertension - Debiopharm to initiate phase III trial for Sanvar in esophageal variceal bleeding

Hypertension - Teva receives tentative approval for generic Cozaar tablets

Hypertension - Treatments for pulmonary arterial hypertension are discussed in review

Hypopharyngeal Cancer - Hypopharyngeal cancer CD105 denotes tumor angiogenesis and patient survival

Imaging - CE-MRI may benefit from long-circulating liposomal contrast agents

Imaging - Necrosis-avid mono-[I-123]iodohypericin is powerful tracer agent for assessing tissue viability

Imaging - Published study examines amino acid chelate technology for linking biotin and avidin to radiotherapeutic isotopes

Immunotherapy - AAAAI reports how to avoid anaphylaxis this summer

Immunotherapy - Antibodies specific for Staphylococcus aureus polysaccharide are characterized

Immunotherapy - Human T cell leukemia virus vaccine reduces proviral load in immunized monkeys

Immunotherapy - Immunotherapeutic potential of adenoviral-mediated gene transfer revealed

Immunotherapy - Immutep: ImmuFact IMP321 successfully completes phase I studies

Infection Management - Infection management is challenging in cancer and stem cell transplant patients

Infectious Diseases -  Bordetella pertussis infection is affected by toll-like receptor 4

Infectious Diseases -  Neisseria spp alpha-2,3-sialyltransferase gene is expressed differentially

Infectious Diseases - Bacterial infections in infants are not associated with any single indicator

Infectious Diseases - Bordetella inhibition of dendritic cell interleukin functions in immune escape

Influenza - ImmuneRegen to respond to U.S. DHHS RFP for new antiviral agents for influenza

Influenza Vaccine - Defective interfering virus is more protective than avirulent virus against influenza A

Influenza Vaccine - PowderMed study reports positive results of DNA-based influenza vaccine in humans

Insulin - Diabetic ketoacidosis can be treated by subcutaneous lispro or intravenous regular insulin

Insulin Resistance - Diabetic models reflect the effect of insulin on vessel formation in obesity

Insulin-like Growth Factor Deficiency - European Commission grants Orphan Medicinal Product Designation to Increlex for primary IGFD

Intravenous Immune Globulin - Current usage of intravenous immune globulin is subject of review

Ischemia - Hypothermic protection against pulmonary ischemia-reperfusion injury depends on endothelial NOS

Kidney Cancer - Targeted therapy shows significant benefits over standard treatment for advanced kidney cancer

Kidney Disease - Calcium-free phosphate binder lanthanum is the focus of review

Kidney Disease - New immortalized glomerular endothelial cells reveal typical responses to VEGF

Kidney Disease - Simvastatin improves sepsis-induced mortality and acute kidney injury

Legal Issues - Federal District Court rules in landmark pharmacy compounding case

Leukemia - Leukemia cells harboring t(15;17) can have PU.1 expression restored by all-trans retinoic acid

Leukemia - Leukemia cells might be selectively inhibited by phenylhexyl isothiocyanate

Leukemia - Leukemia treated with bortezomib experienced enhanced cytotoxic effects of combination chemotherapy

Liver Function - Transforming growth factor is involved with liver cirrhosis

Lung Cancer - Kidney cancer drug also shows promise against advanced form of lung cancer

Lung Cancer - Lung adenocarcinoma affected by antitumor activity of gefitinib

Lung Cancer - Lung cancer developmental signalling pathways studied

Lung Cancer - Lung cancer patients responded well to weekly paclitaxel and carboplatin

Lung Cancer - Lung cancer patients who failed prior platinum-based chemotherapy were treated with docetaxel

Lung Cancer - Lung cancer treatment with docetaxel-cisplatin deemed effective and tolerable

Lung Cancer - Non-small cell lung cancer progression is predicted by genetic mutation and methylation profiles

Lung Cancer - Non-small cell lung cancer should not be treated by postoperative radiotherapy with chemotherapy

Lung Cancer - Point Therapeutics receives fast track designation for talabostat for non-small cell lung cancer

Lung Cancer - Small cell lung cancer treatment should not exclude senior patients

Lupus - Systemic lupus erythematosus risk is associated with regulation of splicing

Lymphangiogenesis - Enhanced macrophage labeling distinguishes tumor macrophages from lymphangiogenesis

Lymphoma - Lymphoma reacted to CHOP plus etoposide and gemcitabine, warranting large-scale trial

Lymphoma Therapy - Frozen plasma and platelet concentrates increase anti-diphtheria toxin IgG concentrations

M. Tuberculosis-Induced Carpal Tunnel Syndrome - MTB-induced carpal tunnel syndrome successfully treated with surgery and anti-infectives

Malaria Therapy - Amodiaquine regimens were not well tolerated for malaria treatment

Malaria Therapy - Enantioselective LC/MS method to determine fenozan B07 in plasma has been developed

Malaria Vaccine - Strain-specific protective immunity in Plasmodium chabaudi chabaudi is examined

Market Analysis - By 2015, the global antiarrhythmic market will be worth $3.5B

Market Analysis - In drug discovery and commercialization, focusing on people optimizes science

Market Analysis - Increase in treatment rates, drug approval will propel growth in bipolar depression market

Market Analysis - Increasing interest in cholesterol-lowering treatment drives phytosterol sales

Market Analysis - Indonesian pharmaceutical market remains complex and competitive

Market Analysis - Life cycle management of pharmaceutical drugs is key to sustaining profitability

Market Analysis - Patients with severe dementia require an additional 41-plus hours of care per week

Market Analysis - Report suggests using marketing expertise to propel timely, successful clinical trials

Market Analysis - U.S.-based drug companies ink copromotion deals to tap European markets

Marketing - Drug ads aimed at cancer patients difficult to read, make more appeals to effectiveness than safety

Medical Research - New York Hospital Queens hosts Research Day, highlights clinical findings and updates

Meningitis Vaccine - Autotransporter protein mediates cell adhesion by Neisseria meningitidis

Mental Health - Number of children and teens treated with antipsychotics increases sharply

Mental Health - Suicide risk in children, teens taking antidepressants may have been exaggerated

Mergers & Acquisitions - 7TM Pharma acquires CareX SA

Mergers & Acquisitions - Adams Respiratory Therapeutics acquires Delsym from UCB

Mergers & Acquisitions - Applied Biosystems to acquire Agencourt Personal Genomics

Mergers & Acquisitions - Avantogen and Innovate complete merger of key oncology program

Mergers & Acquisitions - Bayer amends Schering takeover offer

Mergers & Acquisitions - Bio-Matrix Scientific signs letter of intent to sell unit to Tasco Holdings

Mergers & Acquisitions - Biogen Idec to acquire Fumapharm AG

Mergers & Acquisitions - Biovitrum forms contract research organization

Mergers & Acquisitions - Cardinal Health completes acquisition of pharmaceutical wholesale distribution business

Mergers & Acquisitions - Covance expands its antibody products and services with acquisition of Signet Laboratories

Mergers & Acquisitions - Kensey Nash acquires assets of IntraLuminal Therapeutics

Mergers & Acquisitions - Life Science Pharmaceuticals acquires three monoclonal antibody programs

Mergers & Acquisitions - Parata Systems to acquire McKesson automated prescription systems

Mergers & Acquisitions - Radiant Research completes sale of clinical pharmacology business unit

Mergers & Acquisitions - Trinity Biotech acquires coagulation product line of bioMerieux

Molecular Diagnostics - RAPD technique genotypes coagulase-negative staphylococci strains within 4 hours

Multiple Sclerosis - Teva's Copaxone reduced relapses, stabilized disability when Avonex failed

Muscle Disease - Therapeutic trials and muscular diseases are focus of review

Mycobacterium Ulcerans Drug Resistance - Antibiotics not effective against Mycobacterium ulcerans infection

Myocardial Infarction - Hearts with myocardial infarction may improve upon interleukin-8 stimulation of progenitor cells

Nanotechnology - Nano-fibrous scaffold allows controlled delivery of recombinant human PDGF-BB

Nanotechnology - Nanotechnology holds promise of revolutionizing drug discovery markets

Nasal Polyposis - Nasal polyposis can be treated with oral prednisone followed by intranasal budesonide

Natural Products - Ascitic and solid Ehrlich tumors inhibited by Chenopodium ambrosioides L

Neuroscience - Adult bone marrow stromal cells express genes associated with dopamine neurons

Neuroscience - Beacon immunoreactivity detected in the rat hypothalamus

Neuroscience - Genetically engineered Schwann cells display enhanced migratory potential

Neurotoxicity - Rifampicin attenuates MPTP-induced neurotoxicity

Non-Hodgkin Lymphoma - Risk of non-Hodgkin lymphoma is not associated with use of hormone replacement therapy

Obesity Therapy - T210 plays key role in controlling inactive and active CB1 receptor state transition

Obesity and Hypertension - Moxonidine improved sympathetic nervous activity, insulin resistance, and leptin levels

Obstetrics - Vascular remodeling evaluated by MRI during embryo implantation

Oncology - Ampullary tumors demonstrate a correlation between cyclooxygenase-2 and angiogenesis

Oncology - Hepatocyte growth factor may be a precursor of lymphatic metastasis

Oncology - Myelofibrosis with myeloid metaplasia responds to thalidomide in some patients

Oral Cancer - Oral squamous cell cancer could benefit from identification of diagnostic protein markers

Oral Cancer Implant - Oral cancer implant survival is lower in irradiated mandibles

Oral Health - Periapical lesions exhibit high levels of basic fibroblast growth factor

Orthopedics - Cartilage tumor angiogenesis is regulated by interleukin-1

Orthopedics - Fracture repair is facilitated by placental growth factor

Osteoporosis - Effects of combined hormonal contraception on bone mineral density are focus of review

Osteoporosis - Effects of progestogen-only contraceptive drugs on bone mineral density are reviewed

Osteoporosis - Research clarifies relationship between vitamin D and calcium

Otorhinolaryngology - Sensorineural hearing loss that is sudden may respond to intratympanic dexamethasone

Ovarian Cancer - Cytotoxicity of cisplatin in ovarian carcinoma cells can be modulated by human REV1

Ovarian Cancer - Ovarian cancer risk has been reduced from oral contraceptive usage

Pain Management - Infusion of midazolam and fentanyl provides reliable sedation during mechanical ventilation

Pain Management - ISTA begins phase III trials of a once-daily Xibrom for ocular pain and inflammation

Pain Management - Javelin enrolls first patient in pivotal phase III post-op pain study of Dyloject

Pain Management - New drugs will help drive pain treatment market to $50 billion in 2020

Pancreatic Cancer - Data Safety Monitoring Board recommends Glufosfamide phase III trial continue to completion

Pancreatic Cancer - Lack of studies presented on pancreatic cancer spotlights need for more research

Pancreatic Cancer - Pancreatic cancer cell growth is not influenced by glucagon-like peptide-1 receptor signals

Pancreatic Cancer - Pancreatic cancer responds to matuzumab augmentation of gemcitabine

Pancreatic Cancer - Pancreatic cancer survival benefit after gastrazole treatment requires confirmation in large trial

Pancreatic Cancer - pSivida receives permission to proceed with BrachySil pancreatic cancer trial in U.K.

Pancreatic Cancer - Therion Biologics reports conclusion of Panvac-VF phase III trial

Patents - Antares Pharma, Eli Lilly file joint patent application for needle-free injection device

Patents - BioProgress subsidiary files patent application for use of XGEL film system

Patents - BioTechnology reports basis patent for Sloning gene synthesis technology was granted

Pediatric Cardiology - When a child's heart stops, onset time of abnormal rhythms is crucial

Pediatric Diagnostics - Pediatricians' clinical decision making is influenced by test results

Percutaneous Coronary Intervention - Data indicate a prospective randomized trial of high-dose tirofiban vs. abciximab is warranted

Peripheral Nerve Regeneration - Peripheral nerve regeneration presents a significant clinical challenge

Personnel - AAIPharma appoints VP of European business development

Personnel - Abraxis BioScience appoints new officers to executive management team

Personnel - Advanced Viral Research names Abbott veteran Angelo S. Botter to its board of directors

Personnel - Affymax appoints Kay Slocum as senior VP of human resources

Personnel - Alpharma names Dean J. Mitchell president and CEO

Personnel - Archemix strengthens its board of directors by adding John Maraganore

Personnel - Arius Research hires chief medical officer

Personnel - AtheroGenics names Brian Blakey as VP of marketing

Personnel - Avid Radiopharmaceuticals adds three industry veterans

Personnel - BioScrip announces departure of CFO

Personnel - BioSyntech appoints new board member

Personnel - Carrington promotes Yawei Ni to top scientific post

Personnel - Corgentech announces appointment of Susan Kramer as vice president of preclinical development

Personnel - Dr. Gabor Rubanyi of Berlex Biosciences joins Cardium as chief scientific officer

Personnel - EntreMed appoints new general counsel

Personnel - IOMED appoints D. Stephen Antion to board of directors

Personnel - Michael Hoffman is elected chairman of the board for Onconova

Personnel - MultiCell Technologies appoints Stephen Chang, PhD, as chief executive officer

Personnel - Parexel International appoints Douglas A. Batt as senior vice president and general counsel

Personnel - Stiefel Laboratories appoints Alfonso Ugarte, VP global marketing

Personnel - Symphony Medical names Raymond W. Cohen as CEO

Personnel - Viropro bolsters management team with two new appointments

Personnel - VWR International appoints George Van Kula as senior VP

Personnel - Ziopharm appoints Brian Schwartz as chief medical officer

Pharmaceutical Research - BioInformatics, LLC study shows market for catalog antibodies continues strong growth

Pharmaceutical Research - Cutting Edge Information estimates 43% of pharmaceutical companies outsource market research

Philanthropy - Elizabeth Taylor AIDS Foundation awards grant to AHF's South African AIDS Clinic

Plastic Surgery - Infections of large prosthetic reconstructions about the knee can be salvaged

Professional Education - Pro-Pharmaceuticals' executives contribute to new book, Carbohydrate Drug Design

Prognostics - Effect of age on chemotherapy toxicity requires more clinical detail

Prostate Cancer - Advanced prostate cancer remains sensitive to treatment even after breaks from chemotherapy

Prostate Cancer - AMACR immunohistochemical staining improves detection of small focal prostatic carcinoma

Prostate Cancer - Metastatic prostate cancer prognosis is indicated by key gene polymorphisms

Prostate Cancer - Prostate cancer linked to bone mineral density changes during first 2 years of androgen suppression

Prostate Cancer - Prostate cancer prevented with selenium accumulation in prostate tissue

Prostate Cancer - Prostate cancer progression delayed by celecoxib

Prostate Cancer - Prostate cancer progression may be promoted by human tissue kallikrein 5

Prostate Cancer - Prostate cancer radiation sensitivity selectively enhanced with proteasome inhibition

Prostate Cancer - Prostate cancer risk decreased with regular use of non-steroidal anti-inflammatory drug

Prostate Cancer - Prostate cancer survival predicted by doubling time

Prostate Cancer - Prostate cancer tumorigenesis is modeled in mice expressing a probasin-Neu oncogenic transgene

Proteomics -  Entamoeba histolytica protein displays membrane-fusogenic activity

Proteomics - Myosin and VEGF mediate the angiogenic function of nucleolin

Quality Assurance - Discrepant hypercholesterolemia management guidelines impair consistent prescription

RNA Interference - Mammalian gene expression is artificially controlled by modulating RNA interference

RNA Interference - Short hairpin RNAs delivered into mouse embryonic stem cells

Renal Cell Carcinoma - Renal cell carcinoma treated by preoperative and palliative embolization

Renal Transplantation - Plasma-cell enrichment indicates more adverse outcome in renal transplantation

Respiratory Medicine - Airway inflammation is facilitated by local blockade of T-bet expression

Respiratory Medicine - Sepracor presents arformoterol data at American Thoracic Society International Conference

Rheumatoid Arthritis - Chelsea Therapeutics reports positive clinical results from study of CH-1504

Sepsis - Dopamine is capable of modulating cellular immune functions in a murine model of sepsis

Sepsis - Murine septic shock involves modulation of triggering receptor

Sepsis - Sepsis-related hormone resistance impairs cytokine and growth hormone signaling

Sexual & Reproductive Health - Abortion induced by combined mifepristone and misoprostol appears safe and effective

Sexual & Reproductive Health - Recurrent bacterial vaginosis may be associated with sexual behaviors

Sexual & Reproductive Health - Simultaneous vaginal misoprostol/oral mifepristone therapy produced satisfactory abortion results

Shingles Vaccine - FDA approves Zostavax, Merck's new vaccine for preventing shingles in adults 60 and older

Sickle Cell Disease - Icagen initiates pediatric clinical development of ICA-17043 for sickle cell disease

Smallpox Vaccine - Intradermal immune response after infection with vaccinia virus is described

Solid Tumors - Response of solid tumors to farnesyltransferase inhibitor did not increase with dose escalation

Spermatogenesis - Irradiated testes efficiently support spermatogenesis derived from donor germ cells

Squamous Cell Carcinoma - Squamous cell carcinoma treated by preoperative chemoradiotherapy and surgery

Statins - Statin LDL cholesterol-lowering effect in hypercholesterolemia is described by model

Statins - Statin treatment after acute MI is underused for oldest patients

Steatohepatitis - Chemotherapy can predict steatohepatitis and increased mortality after surgery

Stem Cell Research - 473HD-chondroitinsulfate epitope is involved in neural precursor cell proliferation

Stem Cell Research - Alpha-smooth muscle actin-positive cells play role in cartilage development and maintenance

Stem Cell Research - Bone marrow-derived cells fuse with normal and transformed intestinal stem cells

Stem Cell Research - BrainStorm reports predisposition of bone marrow-derived stem cells to differentiate

Stem Cell Research - Hematopoietic progenitor cell line displays differentiation potential

Stem Cell Research - Novocell, diabetes association announces partnership to clinically test encapsulated human islets

Stem Cell Research - VitroGro technology used to culture human embryonic stem cells

Stem Cell Transplantation - Allogeneic hematopoietic stem cell transplantation favors altered hypothalamic dopaminergic tone

Streptococcus Vaccine - Recombinant Streptococcus gordonii activated naive CD4+ T cells in nasal lymphoid tissue

Stroke - Increased angiogenesis may trigger carotid artery plaque rupture

Surgical Technology - Device closure for atrial septal defect and patent foramen ovale is safe therapeutic option

Thalassemia Therapy - Deferasirox and deferiprone are useful for iron overload in thalassemia major

Thrombosis - Plaque neovascularization may be an offshoot of C-reactive protein expression

Thyroid Cancer - Angiogenesis inhibitor thwarts thyroid carcinoma tumors in mice

Tinnitus - Tinnitus can be effectively treated with gabapentin in some individuals

Tissue Engineering - Accelerated biomimetic coprecipitation yields a bonelike apatite/collagen composite coating

Tissue Engineering - Cell-seeding into 3D porous scaffolds enhanced by use of magnetite nanoparticles

Tissue Engineering - Collagen-based scaffold reinforced by chitin fibers designed for bone tissue engineering

Tissue Engineering - Composite scaffolds developed for vascular tissue engineering

Tissue Engineering - Decellularization efficiency depends on tissue origin and method used

Tissue Engineering - Flat collagen and elastin scaffolds for tissue engineering prepared by freeze-drying

Tissue Engineering - Osteoblast differentiation and matrix mineralization regulated by transglutaminase activity

Tissue Engineering - Tissue engineering scaffolds mimic soft tissue mechanical anisotropy

Tobacco Use - Nabi Biopharmaceuticals initiates phase IIB for NicVax to treat nicotine addiction

Tonsillitis - Advancis Pharmaceutical completes enrollment in Amoxicillin Pulsys phase III trial

Transplant Medicine - Fetal lung tissue might be an option for adult lung regeneration

Transplant Medicine - Rituximab is effective and safe in B-PTLD

Transplant Medicine - Urinary IP-10 expression after kidney transplant may be correlated with graft function

Trypanosomiasis Vaccine - IFN-gamma, nitric oxide, and antibodies promote protection against Trypanosoma

Tuberculosis & Granuloma Formation - Tuberculosis and granuloma formation developed while under infliximab treatment

Tuberculosis Diagnostics - Bone scan demonstrates extent of bone involvement in disseminated tuberculosis

Tuberculosis Epidemiology -  Mycobacterium tuberculosis drug resistance prevalence from 1993-2002 in Greece documented

Tuberculosis Healthcare Cost - Health departments incur substantial cost in managing suspect and noncounted tuberculosis

Tuberculosis Mortality - Risk of death in pulmonary TB increases with number of independent risk factors present

Tuberculosis Treatment - Artificial pneumothorax improves treatment outcome in pulmonary tuberculosis

Tuberculosis Treatment - Tuberculosis treatment completion differs by disease site

Tuberculosis Vaccine - Mycobacterial antigen activates release of proinflammatory cytokines

Type 1 Diabetes - Human insulin inhalation powder and SC insulin similar in efficacy for glycemic control

Urinary Tract Infection - Multifaceted approach decreased postoperative urinary tract infections

Vascular Graft - Vascular graft healing dependent on fluid dynamics in artery-graft-artery construct

Vascular Surgery - Vein graft treatment affects collagen and h-caldesmon levels

Vector Development - Adenoviral delivery of CDC5 promotes cell division in neonatal cardiomyocytes

Vector Development - Method to improve stability of retroviral vectors has been developed

Virology - Cytomegalovirus strains cause mixed infection in immunocompetent mice

Waldenstrom Macroglobulinemia - BLyS inhibition has potential therapeutic potential in Waldenstrom macroglobulinemia

West Nile Virus Vaccine - West Nile Virus DNA vaccine produces neutralizing antibodies in phase I trial

Wet Age-Related Macular Degeneration - Acuity Pharmaceuticals reports positive initial phase II results for Bevasiranib

Wound Healing - Keratinocyte-releasable stratifin facilitates extracellular matrix degradation

Allergies - New findings from Japan, Austria and the United Kingdom in the area of allergies described

Angiology - Data from the United States advance knowledge in angiology research

Angiology - Researchers from the United Kingdom and United States describe findings in angiology studies

Angiology - Researchers' data from the United States, Brazil and Germany advance angiology research

Anthrax - Reports from the United States and People's Republic of China describe recent advances in anthrax research

Apoptosis - Findings from the People's Republic of China, United Kingdom and Greece in apoptosis provide new insights

Apoptosis - Recent findings in apoptosis described by researchers from the United States

Biomedical Engineering - Reports from the United States and Italy advance knowledge in biomedical engineering research

Biomedical Engineering - Researchers from Finland and the United States report details of new studies and findings in the area of biomedical engineering

Breast Cancer - New data from the United States lluminates research in breast cancer

Breast Cancer - New findings from the United States, United Kingdom and Spain in the area of breast cancer detailed

Breast Cancer - New research from Japan, the United States and Greece in the area of breast cancer detailed

Breast Cancer - Recent findings in breast cancer described by researchers from South Korea, United States and Germany

Breast Cancer - Recent studies from Netherlands, Greece and United States add new data to breast cancer research

Breast Cancer - Reports from the United States add new data to breast cancer research

Breast Cancer - Researchers from the United States and Japan provide details of new studies and findings in the area of breast cancer

Breast Cancer - Researchers from the United States and Netherlands report details of new studies and findings in the area of breast cancer

Breast Cancer - Studies from the United States add new findings to breast cancer body of knowledge

Cancer Research - New research from Canada, Denmark and the United States in the area of cancer detailed

Cancer Research - Research from Japan, the United States and the South Korea in cancer provides new insights

Cancer Research - Research from the United States and Australia add new data to cancer body of knowledge

Cancer Research - Researchers from Japan, Finland and the United States detail new studies and findings in the area of cancer

Cancer Research - Researchers from the People's Republic of China, United States and Japan provide details of new studies and findings in the area of cancer

Cancer Treatment - Findings from Belgium, Netherlands and Japan describe new data in cancer treatment research

Cancer Treatment - Findings from Japan and Sweden describe new data in cancer treatment research

Cancer Treatment - Findings from Japan, Australia and Germany in cancer treatment provide new insights

Cancer Treatment - Findings from Mexico and the United States in cancer treatment provide new insights

Cancer Treatment - New data from Australia, Japan and Belgium lluminates research in cancer treatment

Cancer Treatment - New findings from the United States in the area of cancer treatment described

Cancer Treatment - Recent findings from the United States and Italy illuminate research in cancer treatment

Cancer Treatment - Recent findings in cancer treatment described by researchers from the United States and NORTH Ireland

Cancer Treatment - Reports from the United Kingdom, Brazil and United States describe recent advances in cancer treatment research

Cancer Treatment - Reports from the United States and Australia add new data to cancer treatment research

Cancer Treatment - Reports from the United States and France describe recent advances in cancer treatment research

Cancer Treatment - Reports from the United States and the Netherlands add new data to cancer treatment research

Cancer Treatment - Reports from the United States, Japan and Austria advance knowledge in cancer treatment research

Cancer Treatment - Research from Belgium, China and Germany in cancer treatment provides new insights

Cancer Treatment - Researchers from France, the United States and Israel provide details of new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from Italy, Japan and the United States report details of new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from Netherlands, Greece and Italy detail new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from Taiwan and the United States report recent findings in cancer treatment

Cancer Treatment - Researchers from the United States and Germany report recent findings in cancer treatment

Cancer Treatment - Researchers' findings from the Czech Republic, Australia and United States advance cancer treatment research

Cancer Treatment - Studies from Germany, Netherlands and the United States advance knowledge in cancer treatment research

Cancer Treatment - Studies from Japan, the United States and the People's Republic of China describe new findings in cancer treatment research

Cancer Treatment - Studies from Norway, Japan and the People's Republic of China describe new findings in cancer treatment research

Cancer Treatment - Studies from the United States and Belgium advance knowledge in cancer treatment research

Cancer Treatment - Studies from the United States and Japan describe new findings in cancer treatment research

Cardiology - Findings from the United States and Canada advance knowledge in cardiology research

Cardiology - New data from Australia, the United States and Italy lluminates research in cardiology

Cardiology - New findings in cardiology described from the United States, Israel and United Kingdom

Cardiology - Recent studies from Austria, the the Netherlands and the People's Republic of China add new data to cardiology research

Cardiology - Research from the United States add new data to cardiology body of knowledge

Cardiology - Researchers from the United States and Netherlands detail new studies and findings in the area of cardiology

Cardiology - Researchers from the United States, Japan and Switzerland report recent findings in cardiology

Cardiology - Researchers' data from Switzerland, Germany and Denmark advance cardiology research

Cardiology - Researchers' work from the United States, France and Japan adds to cardiology body of knowledge

Cell Biology - Data from France and the United States advance knowledge in cell biology research

Cell Biology - Researchers from Sweden, Japan and Israel provide details of new studies and findings in the area of cell biology

Cell Biology - Researchers' findings from Spain, the United States and the United Kingdom advance cell biology research

Cell Biology - Studies from India, the South Korea and the United Kingdom advance knowledge in cell biology research

Cervical Cancer - Researchers from Netherlands, United States and Belgium detail new studies and findings in the area of cervical cancer

Cholera - Reports from the People's Republic of China, Netherlands and Bangladesh advance knowledge in cholera research

Colorectal Cancer - Researchers' findings from Germany, Denmark and the United States advance colorectal cancer research

Cytomegalovirus - Research from the United States, France and Germany in cytomegalovirus provides new insights

DNA - Reports from Japan and Germany add new data to DNA research

DNA - Researchers from Spain and Japan provide details of new studies and findings in the area of DNA

DNA - Studies from the People's Republic of China and Japan advance knowledge in DNA research

Depression - Researchers' findings from Argentina, India and the United States advance depression research

Diabetes - Data from the United States, Denmark and Japan advance knowledge in diabetes research

Diabetes - Findings from the United States in diabetes provide new insights

Diabetes - New data from Netherlands, United States and United Kingdom lluminates research in diabetes

Diabetes - New findings from Australia, Canada and Norway in the area of diabetes described

Diabetes - New findings from the United States and Israel in the area of diabetes detailed

Diabetes - New findings from the United States and South Korea in the area of diabetes detailed

Diabetes - New research from Japan and Germany in the area of diabetes detailed

Diabetes - Recent findings from Japan, Canada and Belgium illuminate research in diabetes

Diabetes - Recent studies from the United States, Hungary and Wales add new data to diabetes research

Diabetes - Reports from Belgium, France and the United Kingdom add new data to diabetes research

Diabetes - Research from India and Canada in diabetes provides new insights

Diabetes - Research from Japan, Finland and the United States add new data to diabetes body of knowledge

Diabetes - Research from the People's Republic of China, United States and Israel add new data to diabetes body of knowledge

Diabetes - Researchers from Japan, Taiwan and the United States detail new studies and findings in the area of diabetes

Diabetes - Researchers from Japan, the United Kingdom and Canada describe findings in diabetes studies

Diabetes - Researchers from Taiwan, Canada and the United States report details of new studies and findings in the area of diabetes

Diabetes - Researchers from the United States and Germany detail new studies and findings in the area of diabetes

Diabetes - Researchers from the United States provide details of new studies and findings in the area of diabetes

Diabetes - Researchers' data from Spain, Switzerland and the United States advance diabetes research

Diabetes - Studies from Sweden, the United States and Canada describe new findings in diabetes research

Diabetes - Studies from Taiwan, the People's Republic of China and Japan add new findings to diabetes body of knowledge

Drug Development - Researchers' data from the United States and Japan advance drug development research

Enzymology - Reports from the United States and Finland describe recent advances in enzymology research

Gastrointestinal Stromal Tumor - Research from Canada, Poland and Germany in gastrointestinal stromal tumor provides new insights

Gene Therapy - Researchers from Australia and Taiwan publish new studies and findings in the area of gene therapy

Genetics - Findings from the United States in genetics provide new insights

Genetics - Recent findings in genetics described by researchers from the United States, Japan and Austria

Genetics - Researchers from Netherlands, United States and Canada provide details of new studies and findings in the area of genetics

Glioblastoma - Researchers from South Korea, Mexico and United States provide details of new studies and findings in the area of glioblastoma

HIV/AIDS - Findings from the United Kingdom, United States and Norway describe new data in HIV/AIDS research

HIV/AIDS - New findings from Italy, the United States and the United Kingdom in the area of HIV/AIDS described

HIV/AIDS - New findings in HIV/AIDS described from the United States

HIV/AIDS - New research from the United States and Denmark in the area of HIV/AIDS detailed

HIV/AIDS - New research from the United States, Italy and Sweden in the area of HIV/AIDS detailed

HIV/AIDS - Recent findings in HIV/AIDS described by researchers from Belgium, Denmark and Spain

HIV/AIDS - Recent findings in HIV/AIDS described by researchers from the United States

HIV/AIDS - Recent studies from the United States add new data to HIV/AIDS research

HIV/AIDS - Reports from Brazil, Netherlands and France add new data to HIV/AIDS research

HIV/AIDS - Reports from France and the United States advance knowledge in HIV/AIDS research

HIV/AIDS - Reports from the United States advance knowledge in HIV/AIDS research

HIV/AIDS - Reports from the United States and South Africa describe recent advances in HIV/AIDS research

HIV/AIDS - Researchers from the United States and South Africa describe findings in HIV/AIDS studies

HIV/AIDS - Studies from Belgium and the United States advance knowledge in HIV/AIDS research

HIV/AIDS - Studies from the United States and Belgium describe new findings in HIV/AIDS research

HIV/AIDS - Studies from the United States and Brazil add new findings to HIV/AIDS body of knowledge

HIV/AIDS - Studies from the United States and India describe new findings in HIV/AIDS research

Heart Attack - Findings from Netherlands, France and United States describe new data in heart attack research

Heart Attack - New findings from the United States, United Kingdom and Greece in the area of heart attack described

Heart Disease - Researchers' data from Canada, Spain and Italy advance heart disease research

Hematology - Researchers from Finland, Sweden and Germany describe findings in hematology studies

Hepatitis B Virus - New findings from Italy, the United States and the People's Republic of China in the area of hepatitis B virus detailed

Hepatitis B Virus - Researchers' data from South Korea, Taiwan and Japan advance hepatitis B virus research

Hepatitis C Virus - Research from Israel and the United States in hepatitis C virus provides new insights

Hepatitis C Virus - Researchers from Japan, the People's Republic of China and the United States describe findings in hepatitis C virus studies

Hepatitis C Virus - Researchers from the People's Republic of China, Spain and Japan provide details of new studies and findings in the area of hepatitis C virus

Hepatitis C Virus - Studies from Spain, Italy and the United States describe new findings in hepatitis C virus research

Herpes - New findings from Australia and the United States in the area of herpes described

Herpes - Recent findings from the United States, Japan and Sweden illuminate research in herpes

Herpes - Reports from the United States advance knowledge in herpes research

Herpes - Researchers from the United Kingdom, Sweden and United States provide details of new studies and findings in the area of herpes

Hypertension - New research from Japan and Spain in the area of hypertension detailed

Hypertension - Researchers' work from the United Kingdom, France and United States adds to hypertension body of knowledge

Imaging - Researchers from the United Kingdom, Germany and United States report details of new studies and findings in the area of imaging

Influenza - Reports from Bulgaria, the United Kingdom and the United States describe recent advances in influenza research

Influenza - Researchers from Russia and the United States report details of new studies and findings in the area of influenza

Ischemia - New findings from the United States and South Africa in the area of ischemia detailed

Leishmania - Data from India, Germany and the United Kingdom advance knowledge in leishmania research

Leishmania - Findings from the United States and Brazil advance knowledge in leishmania research

Leukemia - Findings from Norway, the United States and Germany describe new data in leukemia research

Leukemia - Researchers from the United States, Japan and Scotland report details of new studies and findings in the area of leukemia

Lung Cancer - Data from South Korea, United Kingdom and Japan advance knowledge in lung cancer research

Lung Cancer - Research from France, Spain and Japan in lung cancer provides new insights

Lung Cancer - Research from Japan, the United States and Italy add new data to lung cancer body of knowledge

Lung Cancer - Studies from the United States, France and Ukraine add new findings to lung cancer body of knowledge

Lymphoma - Recent findings in lymphoma described by researchers from Japan, Germany and Singapore

Malaria - Recent studies from the United States, Australia and the Netherlands add new data to malaria research

Malaria - Researchers from the United States and India report details of new studies and findings in the area of malaria

Melanoma - Research from the United States and the Netherlands in melanoma provides new insights

Melanoma - Researchers from Belgium, Germany and the United States provide details of new studies and findings in the area of melanoma

Melanoma - Researchers from France, Germany and Belgium publish new studies and findings in the area of melanoma

Neurology - New data from France, Japan and Australia lluminates research in neurology

Neurology - New findings from the United States and Japan in the area of neurology described

Neurology - Reports from the United States add new data to neurology research

Obesity - Findings from the United States, Japan and Germany describe new data in obesity research

Obesity - New findings from Australia and the United States in the area of obesity detailed

Obesity - Reports from Italy, Spain and the New Zealand describe recent advances in obesity research

Obesity - Researchers' data from the United States and Japan advance obesity research

Obesity - Researchers' findings from Greece, Canada and the United States advance obesity research

Obesity - Researchers' work from Brazil, the United States and Mexico adds to obesity body of knowledge

Obesity - Studies from France and Japan describe new findings in obesity research

Obesity - Studies from the United States add new findings to obesity body of knowledge

Oncology - Research from South Korea, United States and Italy add new data to oncology body of knowledge

Oncology - Studies from the United States and Japan add new findings to oncology body of knowledge

Ophthalmology - New findings from the People's Republic of China, Japan and United States in the area of ophthalmology described

Osteoporosis - Reports from the United States advance knowledge in osteoporosis research

Pancreatic Cancer - Recent findings in pancreatic cancer described by researchers from France and the United States

Papillomavirus - Reports from South Africa, United States and South Korea add new data to papillomavirus research

Pneumococcal - New research from the United States and Sweden in the area of pneumococcal detailed

Prostate Cancer - Data from the United States and Japan advance knowledge in prostate cancer research

Prostate Cancer - New research from the United States and Australia in the area of prostate cancer detailed

Prostate Cancer - Reports from Canada and the United States add new data to prostate cancer research

Prostate Cancer - Researchers from Germany and the United States report details of new studies and findings in the area of prostate cancer

Prostate Cancer - Researchers from the United States, Canada and United Kingdom publish new studies and findings in the area of prostate cancer

Prostate Cancer - Researchers' data from the United States and People's Republic of China advance prostate cancer research

Prostate Cancer - Researchers' work from Germany, Canada and the United States adds to prostate cancer body of knowledge

Proteins - Recent studies from South Korea, United States and Sweden add new data to proteins research

Rectal Cancer - Findings from Germany, Israel and Italy in rectal cancer provide new insights

Retinopathy - Data from Australia, Japan and the United States advance knowledge in retinopathy research

SARS - Reports from Japan, Austria and the United States describe recent advances in SARS research

SARS - Researchers' findings from the People's Republic of China, Canada and the Netherlands advance SARS research

Statins - Reports from the United Kingdom, Taiwan and Germany add new data to statins research

Surgery - Findings from Canada and the United States describe new data in surgery research

Thyroid Cancer - Findings from Turkey, Italy and Australia describe new data in thyroid cancer research

Transplants - Findings from Brazil, Turkey and Germany in transplants provide new insights

Transplants - Recent findings from the United States illuminate research in transplants

Transplants - Reports from Germany and the United States describe recent advances in transplants research

Transplants - Researchers' work from Turkey, the the Netherlands and Denmark adds to transplants body of knowledge

Vaccines - Findings from Israel, the United States and Germany describe new data in vaccines research

Vaccines - Researchers from the United States, Brazil and Canada report details of new studies and findings in the area of vaccines

Vaccines - Researchers' findings from the United Kingdom, United States and Canada advance vaccines research

Vaccines - Studies from Argentina, Spain and Canada advance knowledge in vaccines research

Vaccines - Studies from the United States, Israel and Netherlands describe new findings in vaccines research

Vectors - New findings from Netherlands and United States in the area of vectors described

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