Cardiology
Regulated transcription factors in proliferating cardiomyocytes clarified
Published in Drug Week, July 28th, 2006
"P38 MAPKs (mitogen-activated protein kinases) play important roles in the regulation of cellular responses to environmental stress. Recently, this signalling pathway has also been implicated in the regulation of processes unrelated to stress, for example, in T lymphocytes and cardiomyocytes.
"In order to identify molecular targets responsible for the housekeeping functions of p38 MAPKs, we have analysed the differences in the transcriptomes of normally proliferating wild-type and p38 alpha knockout...
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Source: Drug Week (2006-07-28)
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