Drug Development
Synthesis of psammaplin A improved
Published in Drug Week, July 28th, 2006
"The marine natural product, psammaplin A, was first isolated from the Psammaplinaplysilla sponge in 1987," investigators in the United States reported.
"Since that time, psammaplin A has shown a wide spectrum of biological activities that include enzyme inhibitory activities resulting in antibacterial and antitumor effects. An improved synthesis of psammaplin A has been developed, making the compound more easily accessible for further biological evaluations," explained A.M. Godert and colleagues, Roswell Park Cancer Institute.
The researchers concluded, "In this context, we...
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Source: Drug Week (2006-07-28)
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