Apoptosis
Human endothelial cells are protected from stress-induced apoptosis by docosahexaenoic acid
Published in Drug Week, July 28th, 2006
According to recent research from Canada, "Induction of apoptosis represents a potential reaction of endothelial cells (ECs) after injury of the vascular endothelium. Beneficial effects of n-3 polyunsaturated fatty acids (PUFAs) in vascular diseases are widely recognized although the responsible mechanisms are not fully understood."
"Because it is not known whether PUFAs modulate EC apoptosis, we investigated the effects of n-3 and n-6 PUFAs on 4-hydroxynonenal (HNE)-induced EC apoptosis by annexin V staining and caspase-3 activation assays," explained C.A....
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Source: Drug Week (2006-07-28)
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