Microtechnology
Human growth hormone achieved using biodegradable polymeric microspheres
Published in Drug Week, July 28th, 2006
"A new approach for attaining sustained release of protein is introduced, involving a pore-closing process of preformed porous poly(D,L-lactic-co-glycolic acid) PLGA microspheres," wrote H.K. Kim and colleagues, Korea Advanced Institute of Science & Technology.
"Highly porous biodegradable PLGA microspheres were fabricated by a single water-in-oil emulsion solvent evaporation technique using Pluronic F127 as an extractable porogen. Recombinant human growth hormone (rhGH) was incorporated into porous...
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Source: Drug Week (2006-07-28)
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