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Merck KgaA, ImClone Systems amend and supplement license, development agreement for Erbitux

Published in Drug Week, August 25th, 2006

Merck KGaA and ImClone Systems Incorporated (IMCL) announced that they have entered into agreements amending and supplementing the 1998 development and license agreement covering Erbitux and certain other work in the field of EGFR-targeted antibodies.

As part of the agreements, ImClone Systems consented to Merck's sublicense of certain intellectual property rights surrounding the development and commercialization of an anti-EGFR antibody to Takeda Pharmaceutical Company. Merck and Takeda signed an alliance in September 2005 for the development and commercialization of matuzumab (EMD72000), a humanized EGFR-targeting monoclonal antibody.

The...

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