Pharmacokinetics

Interactions between simvastatin and omega-3-acid ethyl esters were examined

Published in Drug Week, September 8th, 2006

Researchers examine the pharmacokinetic interaction between simvastatin and prescription omega-3-acid ethyl esters in a recent issue of the Journal of Clinical Pharmacology.

According to a study from the United States and Canada , "The co-administration of prescription omega-3-acid ethyl esters (P-OM3) with a statin may present a treatment option for patients with mixed hyperlipidemia. This open-label, randomized, two-way crossover, drug-drug interaction study evaluated the impact of P-OM3 capsules on plasma simvostatin pharmacokinetics in 24 healthy volunteers."

"Under fasted conditions, 80 mg simvastatin was administered with or without 4 g...

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Source: Drug Week (2006-09-08)

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