Published in Drug Week, September 29th, 2006
According to research from the United States, "The human ATP-binding cassette transporter, ABCG2, confers resistance to multiple chemotherapeutic agents and also affects the bioavailability of different drugs. [125I]Iodoarylazidoprazosin (IAAP) and [3H] azidopine were used for photoaffinity labeling of ABCG2 in this study."
"We show for the first time that both of these photoaffinity analogues are transport substrates for ABCG2 and that [3H] azidopine can also be used to photolabel both...
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