Drug Resistance
Calcium channel blockers are substrates of multidrug resistance-linked ABC drug transporter
Published in Drug Week, September 29th, 2006
According to research from the United States, "The human ATP-binding cassette transporter, ABCG2, confers resistance to multiple chemotherapeutic agents and also affects the bioavailability of different drugs. [125I]Iodoarylazidoprazosin (IAAP) and [3H] azidopine were used for photoaffinity labeling of ABCG2 in this study."
"We show for the first time that both of these photoaffinity analogues are transport substrates for ABCG2 and that [3H] azidopine can also be used to photolabel both...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Drug Week
Source: Drug Week (2006-09-29)
More Articles from Drug Week
- HIV/AIDS Pharmacogenetics
Pharmacogenetic characteristics determined among antiretroviral drugs in HIV/AIDS - Imaging
Risk of contrast-induced nephropathy is highest for iohexol - Market Analysis
All eyes are on Plan B's over-the-counter switch - Rheumatoid Arthritis
Kemia completes successful phase I trials for oral anti-inflammatory drug - Adrenal Cancer
Adrenal malignancy management can include laparoscopic adrenalectomy as an option - Adverse Drug Reaction
Delayed adverse events following intravenous immunoglobulin infusions are common - More from this issue of Drug Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
