HIV/AIDS HAART
Antiretrovirals induce direct endothelial dysfunction
Published in Drug Week, September 29th, 2006
According to a recent study from the United States, "HIV-associated cardiovascular diseases have been widely described, but clinical studies aimed at establishing cause-effect relationships between HIV-associated cardiovascular disease and either the HIV infection or antiretroviral therapy have been problematic.
"Endothelial dysfunction is a sensitive marker and early event in atherosclerosis, and many have suggested that protease inhibitors promote endothelial dysfunction indirectly by inducing elevations in circulating lipids."
"To determine whether nucleoside reverse...
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Source: Drug Week (2006-09-29)
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