Stem Cell Research
p38 MAPK regulate dental pulp cell alkaline phosphatase activity
Published in Drug Week, October 6th, 2006
"The objective of this study was to investigate the implication of p38 mitogen-activated protein kinase (MAPK) in mediating alkaline phosphatase (ALPase) activity in human dental pulp cells (HPCs).
"Nuclear translocation of p38 was observed by immunofluorescence in isolated HPCs treated with transforming growth factor beta 1 (TGF-beta 1). TGF-beta 1 was used to examine the interaction between p38 MAPK and Smad pathway," researchers in the People's Republic of China report.
According to the authors, the role "of p38 kinase in mediating...
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Source: Drug Week (2006-10-06)
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