Endocrinology
Control of estradiol secretion in reproductive aging determined
Published in Drug Week, October 20th, 2006
"E-2 concentration is preserved in older reproductive-aged women despite a decrease in follicle number and androstenedione (AD) levels. We hypothesized that increased aromatase activity accounts for E-2 preservation in older women," wrote C.K. Welt and colleagues, Massachusetts General Hospital.
"Older (36-46 years; n=11) and younger (21-35 years; n=10) women with 25- to 35-day menstrual cycles participated in a parallel design study. Daily blood samples were drawn starting at menses,...
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Source: Drug Week (2006-10-20)
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