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Meningococcal Vaccine

Meningococcal group C vaccine elicits protective immunity within four days upon antigen challenge

Published in Drug Week, October 20th, 2006

Toddlers immunized with meningococcal group C vaccine and challenged one year later with PS antigen elicited protective levels of antibody within four days.

"The contribution of memory responses after meningococcal vaccination to protection may depend on the rapidity of the response. Toddlers were challenged with a licensed polysaccharide (PS) vaccine one year after vaccination with a single dose of meningococcal group C-CRM197 conjugate (MCC) vaccine at the age of 12 to 15 months," an international team of researchers reports.

"Bactericidal antibodies and IgG antibodies detected by ELISA were measured before challenge and 4, 7, 14, or 21...

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