Drug Development
Studies from India and France add new findings to drug development body of knowledge
Published in Drug Week, October 20th, 2006
Study 1: Synthesized compounds are active against isoniazid-resistant Mycobacterium tuberculosis.
According to recent research from India, "A series of N-1-nicotinoyl-3-(4'-hydroxy-3'-methyl phenyl)-5-(substituted phenyl)-2-pyrazolines were synthesized by the reaction between isoniazid (INH) and chalcones and were tested for their antimycobacterial activity in vitro against Mycobacterium tuberculosis H37Rv (MTB) and INH-resistant M. tuberculosis (INHR-MTB) using the agar dilution method."
"Among the synthesized compounds, compound (i)...
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Source: Drug Week (2006-10-20)
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