Breast Cancer Vaccine
Cyclooxygenase-2 inhibitor enhances efficacy of breast cancer vaccine
Published in Drug Week, October 20th, 2006
According to scientists in the United States, "We report that administration of celecoxib, a specific cyclooxygenase-2 (COX-2) inhibitor, in combination with a dendritic cell-based cancer vaccine significantly augments vaccine efficacy in reducing primary tumor burden, preventing metastasis, and increasing survival. This combination treatment was tested in MMTV-PyV NIT mice that develop spontaneous mammary gland tumors with metastasis to the lungs and bone marrow."
"Improved vaccine potency was associated with an increase in tumor-specific CTLs," stated Gargi D. Basu and...
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Source: Drug Week (2006-10-20)
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