Gallbladder Cancer
Gallbladder carcinoma angiogenesis features hypoxia response protein
Published in Drug Week, October 27th, 2006
Researchers in Greece conducted a study "to investigate the significance of the hypoxia inducible factors HIF-1 alpha and HIF-2 alpha in gallbladder adenocarcinomas and their relation to angiogenesis and to the expression of VEGF, an angiogenic factor transcriptionally regulated by HIF alpha. HIF-1 alpha and 2 alpha expression was assessed immunohistochemically in 60 patients with early gallbladder adenocarcinomas, treated with surgery alone.
"In addition, the vascular density (VD) and the expression of the angiogenic factors VEGF and thymidine phosphorylase (TP) were examined. The...
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Source: Drug Week (2006-10-27)
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