Genetics
New findings from the United States, United Kingdom and Japan in the area of genetics detailed
Published in Drug Week, October 27th, 2006
Study 1: According to recently published in the United States, enhanced type I collagen expression influences epigenetic repression of the FLI1 gene in scleroderma fibroblasts.
"Scleroderma (systemic sclerosis; SSc) is an autoimmune disease characterized by vasculopathy and widespread organ fibrosis. Altered fibroblast function, both in vivo and in vitro, is well documented and illustrated by augmented synthesis and deposition of extracellular matrix proteins.
"We undertook this study to investigate the possibility that epigenetic mechanisms...
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Source: Drug Week (2006-10-27)
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