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Escherichia coli

Studies from University of Michigan, Department of Molecular yield new information about escherichia coli

Published in Drug Week, November 3rd, 2006

Research findings, "The Escherichia coli GTPase CgtAE is involved in late steps of large ribosome assembly," are discussed in a new report. According to a study from the United States, "The bacterial ribosome is an extremely complicated macromolecular complex the in vivo biogenesis of which is poorly understood. Although several bona fide assembly factors have been identified, their precise functions and temporal relationships are not clearly defined."

"Here we describe the involvement of an Escherichia coli GTPase, CgtA(E), in late steps of large ribosomal subunit biogenesis. CgtA(E) belongs to the Obg/CgtA GTPase subfamily, whose highly conserved members are...

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