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Angiogenesis

Findings from Kyung-Hee University advance knowledge in angiogenesis

Published in Drug Week, November 17th, 2006

A report, "Potent inhibition of Lewis lung cancer growth by heyneanol A from the roots of Vitis amurensis through apoptotic and anti-angiogenic activities," is newly published data in Carcinogenesis. According to a study from Korea, "Vitis amurensis Rupr. (Vitaceae) has long been used in Chinese/Oriental herbal medicine for the treatment of cancer, but its active compounds and mechanisms of action have not been well studied. To this end, we isolated from its root heyneanol A (HA), which is a tetramer of resveratrol (RES), and established the in vivo antitumor activity of HA using the mouse Lewis lung carcinoma (LLC) model."

"We administered HA and RES by daily...

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