Gene Therapy

Studies from Max Delbruck Center for Molecular Medicine further understanding of gene therapy

Published in Drug Week, November 17th, 2006

Data detailed in "Transposons for gene therapy" have been presented. "Gene therapy is a promising strategy for the treatment of several inherited and acquired human diseases. Several vector platforms exist for the delivery of therapeutic nucleic acids into cells," scientists in Berlin, Germany report.

"Vectors based on viruses are very efficient at introducing gene constructs into cells, but their use has been associated with genotoxic effects of vector integration or immunological complications due to repeated administration in vivo. Non-viral vectors are easier to engineer and manufacture, but their efficient delivery into cells is a major challenge, and the lack of...

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Source: Drug Week (2006-11-17)

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