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Hepatitis Therapy

Study results from Toronto General Hospital update understanding of hepatitis therapy

Published in Drug Week, November 17th, 2006

Research findings, "Murine hepatitis virus strain 1 produces a clinically relevant model of severe acute respiratory syndrome in A/J mice," are discussed in a new report. According to a study from Toronto, Canada, "Severe acute respiratory syndrome (SARS) is a life-threatening infectious disease which has been difficult to study and treat because of the lack of a readily available animal model. Intranasal infection of A/J mice with the coronavirus murine hepatitis virus strain 1 (MHV-1) produced pulmonary pathological features of SARS."

"All MHV-1-infected A/J mice developed progressive interstitial pneumonitis, including dense macrophage infiltrates, giant cells, and...

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